Editorial Material
Multidisciplinary Sciences
Aline Ramires
Summary: Researchers have found that when magic-angle graphene is combined with heavy fermions, the electrons in this pure-carbon material exhibit properties similar to those in heavy-element compounds. A model inspired by this connection reveals how a single-element material can display complex electronic behavior.
Article
Multidisciplinary Sciences
Jieting Chen, Chao Qian, Jie Zhang, Yuetian Jia, Hongsheng Chen
Summary: The authors propose a generation-elimination framework that accurately forecasts inaccessible spectra by correlating spectra from different frequency bands without consulting structural information. This framework accelerates the unification of metasurface designs and enables versatile applications involving cross-wavelength information correlation. The study also introduces a dimensionality reduction approach to visualize the abstract correlated spectra data encoded in latent spaces.
NATURE COMMUNICATIONS
(2023)
Editorial Material
Plant Sciences
Jing Liu, Quan Yuan, Yang Dong
Summary: The study describes the developmental process underlying phyllotaxis establishment in the capitulum of Gerbera hybrida, serving as a cornerstone for studying the development and diversification mechanisms of capitula in the Asteraceae.
TRENDS IN PLANT SCIENCE
(2021)
Review
Chemistry, Inorganic & Nuclear
Abolfazl Ghaderian, Samrana Kazim, Mohammad Khaja Nazeeruddin, Shahzada Ahmad
Summary: Energy conversion through sustainable means is crucial to combat global warming, with molecular ruthenium complexes being key in producing H-2 gas. Different categories of RWOCs have been proposed for improvements, leading to a new family of RWOCs.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Oncology
Serkan Akbulut, Ozgun Erten, Mehmet Gokceimam, Yoo S. Kim, Vikram Krishnamurthy, Katherine Heiden, Judy Jin, Allan Siperstein, Eren Berber
Summary: The study compared the capability to detect parathyroid glands (PG) and image quality between older and newer near-infrared imaging (NIFI) technologies. Results showed that the second-generation NIFI (CMOS) displayed higher detection rates and autofluorescence intensity compared to the first-generation technology (CCD).
JOURNAL OF SURGICAL ONCOLOGY
(2021)
Letter
Gastroenterology & Hepatology
Federica Petrelli, Geri Fratini, Andrea Sbrozzi-Vanni, Andrea Giusti, Raffele Manta, Claudio Vignali, Gabriella Nesi, Andrea Amorosi, Andrea Cavazzana, Marco Arganini, Maria Raffaella Ambrosio
Summary: This report presents a case of peripancreatic paraganglioma initially misdiagnosed as a pancreatic lesion. Surgical exploration revealed the true origins of the mass at the mesocolon root, leading to successful excision and stable postoperative condition. Blinded revision of imaging and cytologic findings highlighted the challenges in accurate pre-operative diagnosis.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Review
Biochemistry & Molecular Biology
Alessandra Ferramosca, Vincenzo Zara
Summary: Yeast mitochondrial carriers play a crucial role in cellular metabolism by connecting mitochondrial and cytosolic reactions, contributing to various important metabolic pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Masamitsu Yamaguchi, Kentaro Omori, Satoshi Asada, Hideki Yoshida
Summary: ALS and CMT are common neurodegenerative disorders with significant phenotypic heterogeneity, potentially due to modifiers that influence disease characteristics. Epigenetic regulation of biological functions through gene expression may be an important mechanism in these diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Surgery
Laura Alberici, Claudio Ricci, Carlo Ingaldi, Riccardo Casadei, Riccardo Turrini, Guido Di Dalmazi, Valentina Vicennati, Uberto Pagotto, Saverio Selva, Francesco Minni
Summary: Independent predictors of operative time include gender, symptoms, previous upper abdominal surgery, size of the lesion, and cumulative sum of procedures. When compared between different surgeons, operative time was significantly longer for the senior surgeon than for the two junior surgeons. The presence of a mentor in the operative theater and specific training programs may be useful during the learning period.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Editorial Material
Oncology
Lee Zou
Summary: This study reveals that heterochromatin-dependent DNA replication stress caused by isocitrate dehydrogenase (IDH) mutants is the reason for the PARP inhibitor sensitivity of IDH mutant cells, rather than HR defects. Additionally, the study demonstrates the crucial role of PARP in responding to replication stress induced by IDH mutants.
Article
Chemistry, Multidisciplinary
Thomas J. O'Connor, Binh Khanh Mai, Jordan Nafie, Peng Liu, F. Dean Toste
Summary: In this study, the copper-catalyzed silylation of propargylic difluorides was successfully used to generate axially chiral, tetrasubstituted monofluoroallenes with good yields and high enantioselectivities. A novel mechanistically distinct reaction was developed, which involves enantiodiscrimination between enantiotopic fluorides to set an axial stereocenter. The effects of the C1-symmetric Josiphos-derived ligand on reactivity and enantioselectivity were investigated, showing that enantioselective beta-fluoride elimination can be achieved in alkenyl copper species.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Polymer Science
Tina Uhlig, Christian Fengler, Andreas Seifert, Florian Taubert, Lysann Kassner, Hans-Joachim Hahnle, Christoph Hamers, Manfred Wilhelm, Stefan Spange, Michael Sommer
Summary: This study reveals that water-soluble bis(N-acylpiperidone)s react rapidly with polyvinylamine to produce clean reaction products, with the resulting hemiaminals, aminals, or mixtures being dependent on pH, water content, and cross-linking density. The network formation is fully reversible upon pH changes, with rheology measurements showing nearly 3 orders of magnitude in moduli. The self-healing ability of the system is demonstrated through rheology testing, indicating the potential of bispiperidones as efficient building blocks in dynamic covalent chemistry.
Article
Environmental Sciences
Menghua Chen, Mengdie Yu, Runfeng Kang, Huimin Sun, Wang Zhang, Shengsen Wang, Nong Wang, Jun Wang
Summary: In this paper, new adsorbents with high mechanical strength, chitosan-graphene oxide and chitosan-titanium dioxide, were synthesized and investigated for their adsorption behavior towards lead and vanadium. The study found that chemical adsorption was the main adsorption force and the Langmuir and Freundlich models fit well with the experimental data.
Article
Materials Science, Multidisciplinary
Yanwu Zhu, Bill Qu, Daria V. Andreeva, Chuanren Ye, Kostya S. Novoselov
Summary: The process of transforming scientific ideas into market products often involves enhancing performance, developing production methods, modifying materials, and establishing relationships between materials suppliers and product manufacturers. Industrial standards play a crucial role in this pathway, as they can either assist or hinder the development of final products.
Article
Biochemistry & Molecular Biology
Qian-Yuan Tang, Weitong Ren, Jun Wang, Kunihiko Kaneko
Summary: The recent development of artificial intelligence has provided new tools for studying the relationship between organism evolution and protein evolution. This study uses AlphaFold DB to analyze proteins from different organisms and finds correlations between organismal complexity and the structure and dynamics of constituent proteins. The study also uncovers the topology and sequence bases of these correlations and suggests a statistical trend of protein evolution parallel to organism evolution. The findings contribute to understanding the origin and evolution of life.
MOLECULAR BIOLOGY AND EVOLUTION
(2022)
Article
Chemistry, Analytical
Yingying Sheng, Ke Zhou, Quansheng Liu, Lei Liu, Hai-Chen Wu
ANALYTICAL CHEMISTRY
(2020)
Review
Biochemistry & Molecular Biology
Sheng Yingying, Zhang Shouwen, Liu Lei, Wu Hai-Chen
Article
Biology
Yanlu Zhao, Minyoung Lim, Sungmoon Choi, Junhua Yu
Summary: The photophysical properties of nanoparticles are essential for cellular imaging. This study reveals the importance of the excitation spectrum in determining the optimal excitation wavelength for nanoparticles, which has been overlooked by chemists and biologists.
JOURNAL OF BIOLOGICAL EDUCATION
(2022)
Article
Chemistry, Analytical
Bingyuan Guo, Peng Song, Ke Zhou, Lei Liu, Hai-Chen Wu
ANALYTICAL CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Hyung Jun Park, Dong Jun Shin, Junhua Yu
Summary: This article clarifies the definitions of four terms: quantum dots, nanodots, nanoclusters, and clusters, presenting their historical usage and research trends over the last five years. Based on the size and photophysical properties of these particles, clear and transferrable definitions are proposed for interdisciplinary use.
JOURNAL OF CHEMICAL EDUCATION
(2021)
Article
Chemistry, Multidisciplinary
Yingying Sheng, Ke Zhou, Lei Liu, Hai-Chen Wu
Summary: This study presents a nanopore sensing assay that accurately quantifies all reaction intermediates and products in enzymatic cascade reactions. The results confirm the existence of substrate channelling in a confined environment. This method is promising for designing and evaluating multienzyme systems.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Kwahun Lee, Insub Jung, Teri W. Odom
Summary: This paper discusses how the order of delivery and endosomal distribution affect endosomal pathways of nanoparticles with different surface curvatures. The results show that the sequential incubation of certain nanoconstructs with macrophages can accelerate the formation of late-stage endosomes and result in larger endosomes. The study also demonstrates that the delivery order and endosomal distribution can affect the subcellular trafficking of targeting nanoconstructs. The paper also presents a new approach for nanoscale monitoring of intracellular therapeutics delivery using conventional electron microscopy.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Divita Mathur, Katherine E. Rogers, Sebastian A. Diaz, Megan E. Muroski, William P. Klein, Okhil K. Nag, Kwahun Lee, Lauren D. Field, James B. Delehanty, Igor L. Medintz
Summary: DNA nanostructures have shown potential in biomedicine, but their intracellular interactions, especially cytosolic stability, are still largely unknown. This study bypassed endocytic uptake to evaluate DNA structural stability directly in live cells, finding that a tetrahedron structure remained intact for at least 1 hour postinjection, while a DNA crosshair degraded rapidly within 20 minutes. The results can inform the design of future DNA nanostructures where programmable degradation rates may be required.
Article
Chemistry, Multidisciplinary
Wei-Hu Hu, Ke Zhou, Lei Liu, Hai-Chen Wu
Summary: A pH-mediated single-molecule switch based on the combination of an alpha-hemolysin nanopore and a hexacyclen-modified DNA strand has been developed. The switch exhibits distinct current transitions when pH is tuned back and forth in a specific range, and it possesses membrane-bound advantages.
Article
Chemistry, Multidisciplinary
Yanlu Zhao, Sungmoon Choi, Sungjay Hong, Eunhye Lee, Junhua Yu
Summary: Controlling the spatial and temporal aspects of fluorogenic reactions is crucial in cellular staining and fluorophore printing. This study demonstrates the selective generation of versatile spectrally pure luminescent silver nanodots by transferring silver clusters from polymers to single-stranded DNA (ssDNA). This transfer process dramatically enhances the emission intensity of the silver nanodots and offers advantages in terms of spectral range and speed of fluorophore generation. Additionally, multiple silver nanodots can be generated in a single step, making it applicable for visualizing printed ssDNA on silver nanodots in solution and on surfaces.
ADVANCED MATERIALS INTERFACES
(2022)
Article
Chemistry, Physical
Ajmeeta Sangtani, Kwahun Lee, Okhil K. Nag, Kimihiro Susumu, R. Joseph Weiblen, Mijin Kim, Igor Vurgaftman, Sz-Chian Liou, James B. Delehanty, Eunkeu Oh
Summary: Thiol-based ligands are commonly used for surface modification of metal nanoparticles, but the direct synthesis of non-spherical gold nanoparticles has been limited. In this study, we developed a one-step method to synthesize multipod-shaped gold nanoparticles by controlling the reducing power, acidity, and reagent stoichiometry. The physicochemical properties of these gold nanoparticles can be modulated by modifying the terminal groups and length of the ligands.
CHEMISTRY OF MATERIALS
(2022)
Article
Multidisciplinary Sciences
Weichao Peng, Shuaihu Yan, Ke Zhou, Hai-Chen Wu, Lei Liu, Yuliang Zhao
Summary: By using a modified density gradient ultracentrifugation method, ultrashort single-walled carbon nanotubes (SWCNTs) with a narrow conductance range can be separated and inserted into lipid bilayers to construct high-resolution nanopore sensors. These SWCNT nanopores exhibit 3-5 times higher ion mobility compared to bulk mobility, and are capable of discriminating homologous and isomeric proteinogenic amino acids, which is challenging for other types of nanopore sensors. These findings hold great importance for the development of protein sequencing technologies.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Eunhye Lee, Sungmoon Choi, Yanlu Zhao, Junhua Yu
Summary: This study utilizes luminescent poly(acrylic acid) (PAA)-stabilized silver nanodots (PAA-AgNDs) as a turn-on sensor to monitor the interaction between the PAA chain and its binding cations. The binding of cations cross-links the linear PAA chain, enhances the emission of silver nanodots, and induces a blue-shift of its emission spectrum. Calcium ions show the strongest bonding to the PAA polymer chain among Group 2 cations. The research also demonstrates that luminescent silver nanodots can be excellent probes for the detection of polymer activities with straightforward visualization methods.
Review
Pharmacology & Pharmacy
Okhil K. Nag, Kwahun Lee, Michael H. Stewart, Eunkeu Oh, James B. Delehanty
Summary: This review summarizes the progress made over the past 5 years in the use of various nanoparticle bioconjugates for the therapeutic delivery of nitric oxide. The advantages and challenges of using these materials for controlled nitric oxide delivery are discussed. Nitric oxide plays critical roles in cellular health and disease, but its physicochemical properties present challenges for specific and efficient delivery. Recent research has focused on utilizing nanoparticle carriers to enhance nitric oxide delivery.
THERAPEUTIC DELIVERY
(2022)
Article
Chemistry, Multidisciplinary
Sungjay Hong, Yanlu Zhao, Sungmoon Choi, Eunhye Lee, Junhua Yu
Summary: Silver nanodots, which emit predominantly near-IR, can be instantly created on a surface through silver cluster transfer. The reorganization of these nanodots is limited by the presence of ssDNA molecules on the surface. Adjusting the freedom of the adsorbed ssDNA allows for the generation of various types of silver nanodots on the surface.
CHEMICAL COMMUNICATIONS
(2022)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
