4.7 Article

A simple base-mediated amidation of aldehydes with azides

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CHEMICAL COMMUNICATIONS
卷 49, 期 12, 页码 1193-1195

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc37289d

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  1. James and Esther King Biomedical Research Program [07KN-08]

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A practical and efficient amidation reaction involving aromatic aldehydes and various azides under mild conditions is described. A broad spectrum of functional groups was tolerated, and the amides were synthesized in moderate to excellent yields, presenting an attractive alternative to the currently available synthetic methods.

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