Article
Biophysics
Omur Acet, Dzmitry Shcharbin, Victoriya Zhogla, Pavel Kirsanov, Inessa Halets-Bui, Burcu Onal Acet, Tuba Gok, Maria Bryszewska, Mehmet Odabasi
Summary: Short peptides are versatile and flexible in the design of self-assembled materials. Self-assembled dipeptides, a group of peptide nanostructures, have attractive uses in biomedicine due to their biocompatibility, low-cost, simplicity of synthesis, functionality, and nano dimensions. More information is needed to explore the advantages, challenges, importance, synthesis, interactions, and applications of self-assembled dipeptide nanostructures, especially for biomedical purposes.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Organic
Ji-Wei Ren, Meng-Nan Tong, Yu-Fen Zhao, Feng Ni
Summary: An efficient triphenylphosphine oxide-catalyzed amidation and esterification reaction has been developed for the rapid synthesis of various dipeptides, amides, and esters. This reaction is suitable for challenging couplings of hindered carboxylic acids with weakly nucleophilic amines or alcohols, providing products in high yields without racemization. The system utilizes the highly reactive intermediate Ph3PCl2 as the activator of the carboxylate and drives the reaction to completion in a short reaction time.
Article
Materials Science, Multidisciplinary
Qi Li, Mingju Xian, Anhe Wang, Yi Jia, Shuo Bai, Xuehai Yen, Junbai Li
Summary: Dipeptides are biocompatible building blocks that can be assembled into various sensing materials. These sensors interact with force, electricity, light, and chemical stimulus to generate electrical, optical, and mechanical signals, making them applicable in microelectronics and healthcare fields. Dipeptide-based sensing materials have the advantages of biological molecules and also possess excellent mechanical and electrical properties. This perspective article summarizes the molecular assembly of dipeptides, focusing on their application as biogenic sensors, and discusses the challenges and prospects for the future development of dipeptide-based sensing materials.
Article
Chemistry, Multidisciplinary
Kohei Sato, Charlotte E. Farquhar, Jacob Rodriguez, Bradley L. Pentelute
Summary: An expansion of the hexanucleotide repeat sequence in the chromosome 9 open frame 72 (c9orf72) is the most common genetic mutation in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). This mutation leads to the production of toxic dipeptide repeat proteins (DPRs) that induce neurodegeneration. In this study, the researchers synthesized various DPRs using automated fast-flow peptide synthesis (AFPS) and revealed their physical properties, including secondary structures. They also demonstrated the cytotoxic effects of specific DPRs on human neuroblastoma cells. This research highlights the potential of AFPS in synthesizing peptides and proteins for studying disease mechanisms and constructing disease models.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Polymer Science
Chaojie Li, Jiannan Cheng, Yi Zhang, Qing Yu, Zhiru Yuan, Weiwei He, Xiaoguang Bao, Lifen Zhang, Zhenping Cheng
Summary: Fluorinated polymers, although fascinating, have not been widely applied in daily life due to restricted synthetic methodology and limited availability of monomers. In this work, main-chain-type semifluorinated alternating terpolymers (SFATs) were synthesized using a step transfer-addition and radical-termination (START) polymerization strategy. The synthesis was achieved by irradiation with visible light at room temperature using NaI as the catalyst. The work provides a guide for the synthesis of a broad range of fluorinated polymers by increasing participating monomers and facilitating the integration of desirable properties.
Review
Chemistry, Inorganic & Nuclear
Ahmed Alzamly, Maram Bakiro, Salwa Hussein Ahmed, Lamia A. Siddig, Ha L. Nguyen
Summary: This review provides a comprehensive overview of the application of metal-organic frameworks (MOFs) as catalysts for alpha-olefin oligomerization and polymerization. Designed MOFs, MOFs with postsynthetic modification, and MOFs with mixed-metal clusters are discussed. The use of MOFs as non-selective catalysts for alpha-olefin oligomerization and polymerization is also presented. Challenges and perspectives for future research are highlighted.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Physical
Dario Barreiro-Lage, Paola Bolognesi, Jacopo Chiarinelli, Robert Richter, Henning Zettergren, Mark H. Stockett, Laura Carlini, Sergio Diaz-Tendero, Lorenzo Avaldi
Summary: The study demonstrates that the interaction of VUV radiation with DKPs produces reactive intermediates, which can either reconstruct cyclic dipeptides or form longer linear peptide chains. These findings shed light on the survival and amino acid polymerization processes of DKPs.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Physical
Jorge M. del Campo, Joel Ireta
Summary: The hydrophobic dipeptide crystals are unusually stiff, with Young's moduli in the range of 19.7-33.3 GPa, primarily dictated by the strength and orientation of the hydrogen bond network.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Jiwei Min, Jiayu Liu, Zixuan Wang, Yuefei Wang, Yu Zhou, Liwei Zhang, Jiaxing Zhang, Yuhe Shen, Qing Li, Rongxin Su, Wei Qi
Summary: This study reveals that short peptides can form various chiral nanostructures mediated by metal ions and highlights their potential applications in catalysis and antimicrobials.
Article
Chemistry, Multidisciplinary
Remi Beucher, Vasile Hulea, Claudia Cammarano
Summary: A kinetic study of ethylene oligomerization on mesoporous 2 wt% Ni-AlKIT-6 was conducted in a fixed bed flow reactor. The main products identified were n-butenes and hexenes. The proposed Cossee-Arlman coordination-insertion mechanism explained the formation of these primary products. An activation energy and global kinetic order were determined, suggesting that ethylene insertion into the metal-alkyl bond is the kinetically limiting step.
REACTION CHEMISTRY & ENGINEERING
(2021)
Article
Agricultural Engineering
Matthias Betz, Constantin Fuchs, Thomas A. Zevaco, Ulrich Arnold, Jorg Sauer
Summary: In the field of gasoline synthesis from renewable resources, highly integrated procedures are crucial for efficient and sustainable production. Ethylene oligomerization can produce gasoline-type hydrocarbons. Temperature and pressure significantly affect the selectivity and intramolecular branching. The catalyst showed stable performance under the tested conditions.
BIOMASS & BIOENERGY
(2022)
Article
Oncology
Ok-Jin Park, Yeongkag Kwon, Jiseon Kim, Chaeyeon Park, Cheol-Heui Yun, Seung Hyun Han
Summary: This study found that muramyl dipeptide (MDP) can alleviate post-menopausal osteoporosis through the regulation of Wnt signaling. MDP increases bone volume and bone mineral density, promotes bone formation, and inhibits osteoclast activity. These findings have significant implications for the treatment of post-menopausal bone loss.
JOURNAL OF PATHOLOGY
(2023)
Article
Polymer Science
Ryo Yonenuma, Hideharu Mori
Summary: A hybrid monomer consisting of diphenylalanine and tetraphenylethylene (TPE) was synthesized and used for polymerization. The monomer formed self-assembled structures and exhibited aggregation-induced emission (AIE) properties. The resulting polymers showed stable assembled structures with characteristic emissions and AIE properties. This study demonstrated the potential of the diphenylalanine-TPE hybrid monomer for the development of chiral AIE hybrid polymers.
Article
Food Science & Technology
Yongqiu Yan, Mingliang Li, Ying Wei, Fuhuai Jia, Yanying Zheng, Gang Tao, Feifei Xiong
Summary: This study evaluates the impact of three dipeptides derived from oysters on the oxidative stress state of TM3 cells induced by AAPH, while also examining changes in cellular testosterone biosynthesis capacity. The results suggest that these three dipeptides improve cellular oxidative stress by directly scavenging excess ROS or reducing ROS production, rather than enhancing cellular antioxidant capacity through modulation of antioxidant enzyme activity.
FOOD SCIENCE & NUTRITION
(2023)
Review
Chemistry, Multidisciplinary
Liangchun Li, Li Xie, Renlin Zheng, Rongqin Sun
Summary: This review discusses the design and structures of self-assembly linear dipeptide hydrogels, as well as the strategies for preparing the new generation of hydrogels. With a deeper understanding of the relationship between the structures and properties of dipeptides, it is believed that dipeptide hydrogels have great potential in preparing minimal biocompatible materials.
FRONTIERS IN CHEMISTRY
(2021)
Article
Biochemical Research Methods
Wenchun Xie, Xu Qin, Iwao Teraoka, Richard A. Gross
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2013)
Article
Chemistry, Multidisciplinary
Xu Qin, Wenchun Xie, Sai Tian, Jiali Cai, Han Yuan, Zheng Yu, Glenn L. Butterfoss, Anne C. Khuong, Richard A. Gross
CHEMICAL COMMUNICATIONS
(2013)
Article
Biochemical Research Methods
Wenchun Xie, Xu Qin, Iwao Teraoka, Richard A. Gross
JOURNAL OF CHROMATOGRAPHY A
(2011)
Correction
Biochemical Research Methods
Wenchun Xie, Xu Qin, Iwao Teraoka, Richard A. Gross
JOURNAL OF CHROMATOGRAPHY A
(2012)
Article
Chemistry, Multidisciplinary
Geng Li, Jun Wu, Xu Qin, Jianhui Zhu, Kodandaraman Viswanathan, He Dong, P. Somasundaran, Richard A. Gross
Article
Chemistry, Physical
Xu Qin, Wenchun Xie, Qi Su, Wenzhe Du, Richard A. Gross
Article
Chemistry, Physical
Xu Qin, Wenchun Xie, Sai Tian, Mohamed Abo Ali, Abhijeet Shirke, Richard A. Gross
Meeting Abstract
Chemistry, Multidisciplinary
Xu Qin, Wenchun Xie, Jianhui Zhu, Richard A. Gross
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
Meeting Abstract
Chemistry, Multidisciplinary
Wenchun Xie, Xu Qin, Iwao Teraoka, Richard A. Gross
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
Meeting Abstract
Chemistry, Multidisciplinary
Xu Qin, Wenchun Xie, Qi Su, Wenzhe Du, Richard A. Gross
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
Meeting Abstract
Chemistry, Multidisciplinary
Xu Qin, Anne C. Khuong, Richard A. Gross
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
Meeting Abstract
Chemistry, Multidisciplinary
Richard A. Gross, Kodandaraman Viswanathan, Xu Qin, Wenchun Xie, Geng Li
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)