期刊
CHEMICAL COMMUNICATIONS
卷 49, 期 2, 页码 184-186出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc36811k
关键词
-
Chelation of Cu(I) ions to an immobilized hydrophilic tris(triazolylmethyl) amine chelator on a solid support allowed synthesis of RNA oligonucleotide conjugates from completely deprotected alkyne-oligonucleotides. No oligonucleotide strand degradation or metal ion contamination was observed. Furthermore, use of the immobilized copper(I) ion overcame regioselectivity issues associated with strainpromoted copper-free azide-alkyne cycloaddition.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据