Article
Chemistry, Multidisciplinary
Saquib Ahmed M. A. Peerzade, Nadezhda Makarova, Igor Sokolov
Summary: The mesoporous nature of silica nanoparticles allows for the development of ultrabright fluorescent particles by physically encapsulating organic molecular fluorescent dyes inside the pores. These particles can be used to assemble ultrabright fluorescent ratiometric sensors for simultaneous pH and temperature measurements with high sensitivity and stability.
Article
Chemistry, Analytical
Xiao Liu, Xiangyang Gong, Jie Yuan, Xiaopeng Fan, Xingxing Zhang, Tianbing Ren, Sheng Yang, Ronghua Yang, Lin Yuan, Xiao-Bing Zhang
Summary: A new dual-stimulus responsive near-infrared reversible ATP-pH probe has been developed for fluorescence and photoacoustic ratiometric imaging of tumors, effectively reducing cumulative response after intravenous injection and suitable for in vivo imaging.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Junxiang Peng, Hongxia Chen, Mingtai Sun, Huan Yu, Jing Hou, Suhua Wang
Summary: The balance of acid-base levels is crucial for cellular functions and diseases prevention. A newly developed ratiometric fluorescent probe Ox-L based on 3H-indolium dye shows high sensitivity for detecting intracellular pH fluctuations, indicating great potential for biological applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Spectroscopy
Dongyuan Wang, Qiang Yin, Ming Zheng, Yongbo Xie, Wen He, Zheng Li, Sanying Hou, Hongqing Wang
Summary: A novel Zn2+ fluorescent sensor with larger Stokes shift and high selectivity was designed and synthesized, showing high sensitivity and linear response range in DMF-H2O solution. The interaction properties and fluorescence mechanism of TPA-PN and zinc were investigated using various methods.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Applied
Brenda G. Molina, Roshan B. Vasani, Karyn L. Jarvis, Elaine Armelin, Nicolas H. Voelcker, Carlos Aleman
Summary: We have developed a flexible system that can release antibiotic and act as a pH sensor under electrostimulation. This system has dual pH and electro-responsiveness and has been tested on bacterial strains for its effectiveness.
REACTIVE & FUNCTIONAL POLYMERS
(2022)
Article
Chemistry, Analytical
Wenwen Ma, Ruiming Chen, Tingting Hu, Shu Xing, Guanglian Zhou, Xiaoxu Qin, Huijun Ren, Zhengyang Zhang, Jianbin Chen, Qingfen Niu
Summary: To detect cyanide and hypochlorite anions in environmental and biological samples, a new molecular sensor based on oligothiophene and Meldrum's acid units was developed. The sensor exhibited high selectivity, excellent sensitivity, short response time, and a broad pH working range. It was successfully applied for the detection of hypochlorite and cyanide in real-world samples and bioimaging in live cells and zebrafish, making it the seventh single-molecular sensor capable of simultaneous and discriminative detection in various environments.
Article
Chemistry, Multidisciplinary
Shiya Chen, Mingjian Chen, Jinfeng Yang, Xianqing Zeng, Yibo Zhou, Sheng Yang, Ronghua Yang, Quan Yuan, Jing Zheng
Summary: Hypoxia and acidic pH are chosen as dual stimuli to fabricate a dual lock-and-key fluorescent nanoprobe for highly specific and precise imaging of tumor cells. This nanoprobe successfully applies in a tumor-bearing mice model, indicating the potential for early diagnosis and assessment of cancer treatment.
Article
Pharmacology & Pharmacy
Yanbing Wang, Xiaolei Wang, Yingni Lv, Yinghua Guo, Muye He, Minbo Lan, Yuzheng Zhao, Feng Gao
Summary: Oxidative stress is crucial in the pathogenesis of inflammatory bowel disease, and the TotalROX probe combined with an oral nanoparticle delivery system can effectively detect the degree of colitis. Experimental results show that TotalROX nanoparticles have the potential to image cells effectively.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Applied
Zhong Lin, Heru Pan, Yong Tian, Jia Tang, Chonghua Zhang, Peisheng Zhang, Heping Yang, Jian Chen
Summary: This paper reports the fabrication of novel photo-pH dual stimuli-responsive multicolor fluorescent polymeric nanoparticles (SMFPNs) through combination of one-pot miniemulsion polymerization and surface modification, which can achieve multi-color transformation of blue, green, and red under changing pH and illumination conditions.
Article
Nanoscience & Nanotechnology
Xuemeng Yang, Shufang Lv, Tianci Li, Shuai Hao, Hongnan Zhu, Yan Cheng, Shuaijie Li, Hongzan Song
Summary: In this study, a stretchable, dual thermo-responsive and strain-responsive ionogel was synthesized using a one-step photopolymerization method. The resulting ionogel exhibited high stretchability, high ionic conductivity, and good temperature tolerance. It also showed a tunable phase-transition temperature and reversible color/transparency switching. The ionogel-based temperature monitors, smart windows, and strain sensors demonstrated excellent designability, programmability, temperature modulation ability, and thermal responsiveness. This approach holds great promise for the development of multifunctional stimuli-responsive materials.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Pharmacology & Pharmacy
Sikhumbuzo Charles Kunene, Kuen-Song Lin, Meng-Tzu Weng, Maria Janina Carrera Espinoza, You-Sheng Lin, Chun-Ming Wu, Wei-Chin Tsai
Summary: Liver cancer is difficult to treat due to its high recurrence and metastasis rates. Polymeric nanogels have emerged as a promising treatment method. In this study, pH- and thermo-dependent polymeric core-shell microgels encapsulating doxorubicin (DOX) were prepared. The microgels showed well-defined core-shell nanostructures and demonstrated nontoxicity and biocompatibility towards normal and cancer cell lines. The drug release profiles indicated pH- and thermo-responsive behavior. The prepared microgels could potentially serve as novel drug carriers for delivering DOX to liver cancer cells.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Ying Lian, Zhenzhen Lin, Zeyu Zhang, Xu-dong Wang
Summary: The study developed a dual nanosensor that can simultaneously detect oxygen and pH in mitochondria with high sensitivity, stability, and low cytotoxicity. By applying it to HeLa cells, real-time measurement and imaging of mitochondrial oxygen and proton concentration variations were successfully achieved.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Jian-Yu Wang, Feng Jin, Xian-Zi Dong, Jie Liu, Ming-Xia Zhou, Teng Li, Mei-Ling Zheng
Summary: This study demonstrates a dual-stimuli cooperative responsive hydrogel microactuator by asymmetric fabrication via femtosecond laser direct writing. The dual response of the hydrogel microstructure is achieved through the use of responsive hydrogel with functional monomer 2-(dimethylamino)ethyl methacrylate. Raman spectra of the hydrogel microstructures suggest that the pH and temperature response of the hydrogel is generated by the changes in tertiary amine groups and hydrogen bonds, respectively. The asymmetric hydrogel microstructures show opposite bending direction when being heated to high temperature or exposed to acid solution, and can independently accomplish the grasp of polystyrene microspheres.
Article
Chemistry, Physical
Mehmet Oguz, Alev Gul, Ahmed Nuri Kursunlu, Mustafa Yilmaz
Summary: This study developed a new cheap-facile and bifunctional fluorescent sensor for toxic ions, using fluorometric and colorimetric methods to determine the binding modes and performance of the sensor. Additionally, the sensor was successfully applied for ion detection in living cells.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
Han Wei, Yifang Yu, Guanghua Wu, Yueqin Wang, Shuyi Duan, Jinyan Han, Weiyan Cheng, Cai Li, Xin Tian, Xiaojian Zhang
Summary: The dual-responsive fluorescent probe 3Q-2 can reveal dynamic changes in NAD(P)H and mitochondrial viscosity during ferroptosis, a newly discovered form of cell death. This probe displays two separate spectra in response to NAD(P)H and mitochondrial viscosity with high sensitivity and selectivity. Cancer cells exhibit distinct levels of NAD(P)H and mitochondrial viscosity during ferroptosis induced by specific inhibitors. This robust method of detecting NAD(P)H and mitochondrial viscosity simultaneously may find applications in various physiological and pathological scenarios.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Yang Wang, Hongkun Xiang, Rongrong Zhao, Chusen Huang
Article
Chemistry, Multidisciplinary
Luling Wu, Yang Wang, Tony D. James, Nengqin Jia, Chusen Huang
CHEMICAL COMMUNICATIONS
(2018)
Article
Chemistry, Multidisciplinary
Luling Wu, Qingye Yang, Liyuan Liu, Adam C. Sedgwick, Alexander J. Cresswell, Steven D. Bull, Chusen Huang, Tony D. James
CHEMICAL COMMUNICATIONS
(2018)
Article
Chemistry, Multidisciplinary
Houna Duan, Yu Ding, Chusen Huang, Weiping Zhu, Rui Wang, Yufang Xu
CHINESE CHEMICAL LETTERS
(2019)
Article
Materials Science, Biomaterials
Zhiming Wang, Lina Chen, Zhongyun Chu, Chusen Huang, Yuankui Huang, Nengqin Jia
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2018)
Article
Chemistry, Analytical
Minghuan Liu, Yanan Xu, Chusen Huang, Ti Jia, Xiaoyan Zhang, Da-Peng Yang, Nengqin Jia
Article
Chemistry, Analytical
Da-Peng Yang, Weiwei Guo, Zhengfa Cai, Yisong Chen, Xingsheng He, Chusen Huang, Junyang Zhuang, Nengqin Jia
SENSORS AND ACTUATORS B-CHEMICAL
(2018)
Article
Chemistry, Multidisciplinary
Luling Wu, Hai-Hao Han, Liyuan Liu, Jordan E. Gardiner, Adam C. Sedgwick, Chusen Huang, Steven D. Bull, Xiao-Peng He, Tony D. James
CHEMICAL COMMUNICATIONS
(2018)
Article
Chemistry, Multidisciplinary
Luling Wu, Yang Wang, Maria Weber, Liyuan Liu, Adam C. Sedgwick, Steven D. Bull, Chusen Huang, Tony D. James
CHEMICAL COMMUNICATIONS
(2018)
Article
Materials Science, Biomaterials
Xiaolin Li, Rongrong Zhao, Yang Wang, Chusen Huang
JOURNAL OF MATERIALS CHEMISTRY B
(2018)
Article
Chemistry, Analytical
Huan Zhang, Hong Ke, Yinfang Wang, Pengwei Li, Chusen Huang, Nengqin Jia
Article
Materials Science, Biomaterials
Zhongyun Chu, Lina Chen, Xiaoshuang Wang, Qingye Yang, Qi Zhao, Chusen Huang, Yuankui Huang, Da-Peng Yang, Nengqin Jia
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2019)
Article
Materials Science, Biomaterials
Rongrong Zhao, Ti Jia, Hongyuan Shi, Chusen Huang
JOURNAL OF MATERIALS CHEMISTRY B
(2019)
Correction
Chemistry, Multidisciplinary
Luling Wu, Yang Wang, Maria Weber, Liyuan Liu, Adam C. Sedgwick, Steven D. Bull, Chusen Huang, Tony D. James
CHEMICAL COMMUNICATIONS
(2019)
Article
Chemistry, Multidisciplinary
Shuai Zhang, Khaleel I. Assaf, Chusen Huang, Andreas Hennig, Werner M. Nau
CHEMICAL COMMUNICATIONS
(2019)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
