期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 34, 页码 4124-4126出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc30627a
关键词
-
资金
- Organic Synthesis Based on Reaction Integration [21390030, 22106515, 2105]
- Asahi Glass Foundation
Organic base-catalyzed reaction of (S)-N-tert-butanesulfinyl (3,3,3)-trifluoroacetaldimine with dialkyl malonates was found to be effective for synthesis of both (S,S-S) and (R,S-S) beta-amino-malonates in high yield with good to excellent diastereoselectivity (76-98% de). The products of this Mannich reaction provide direct access to beta-trifluoromethyl-beta-alanine of either (R) or (S) absolute configuration.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据