期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 76, 页码 9507-9509出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc34848a
关键词
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资金
- National Key Scientific Program of China [2011CB911000]
- NSFC [20975034, 21177036]
- National Key Natural Science Foundation of China [21135001]
- National Instrumentation Program [2011YQ030124]
- Ministry of Education of China [20100161110011]
- Hunan Provincial Natural Science Foundation [11JJ1002]
A proximity-dependent surface hybridization strategy is employed for designing a signal-on electrochemical DNAzyme biosensor. By taking advantage of the high sensitivity of the PDSH strategy, and by realizing the enzymatic hydrolysis reaction in a homogenous system with a unimolecular design, the proposed biosensor shows a very high sensitivity to target molecules.
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