In silico design, synthesis and evaluation of 3′-O-benzylated analogs of salacinol, a potent α-glucosidase inhibitor isolated from an Ayurvedic traditional medicine “Salacia”

Isolation, structure identification and SAR studies on thiosugar sulfonium salts, neosalaprinol and neoponkoranol, as potent α-glucosidase inhibitors

(2011) Weijia Xie et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mapping the intestinal alpha-glucogenic enzyme specificities of starch digesting maltase-glucoamylase and sucrase-isomaltase

(2011) Kyra Jones et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Biological evaluation of 3′-O-alkylated analogs of salacinol, the role of hydrophobic alkyl group at 3′ position in the side chain on the α-glucosidase inhibitory activity

(2011) Genzoh Tanabe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Study of the inhibition of two human maltase-glucoamylases catalytic domains by different α-glucosidase inhibitors

(2011) Limei Ren et al.   CARBOHYDRATE RESEARCH

The effect of heteroatom substitution of sulfur for selenium in glucosidase inhibitors on intestinal α-glucosidase activities

(2011) Razieh Eskandari et al.   CHEMICAL COMMUNICATIONS

Probing the active-site requirements of human intestinal N-terminal maltase glucoamylase: The effect of replacing the sulfate moiety by a methyl ether in ponkoranol, a naturally occurring α-glucosidase inhibitor

(2010) Razieh Eskandari et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Docking and SAR studies of salacinol derivatives as α-glucosidase inhibitors

(2010) Shinya Nakamura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structural Basis for Substrate Selectivity in Human Maltase-Glucoamylase and Sucrase-Isomaltase N-terminal Domains

(2010) Lyann Sim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative analysis of neosalacinol and neokotalanol, another two potent α-glucosidase inhibitors from Salacia species, by LC-MS with ion pair chromatography

(2010) Osamu Muraoka et al.   Journal of Natural Medicines

Towards the elusive structure of kotalanol, a naturally occurring glucosidase inhibitor

(2010) Sankar Mohan et al.   NATURAL PRODUCT REPORTS

New Glucosidase Inhibitors from an Ayurvedic Herbal Treatment for Type 2 Diabetes: Structures and Inhibition of Human Intestinal Maltase-Glucoamylase with Compounds fromSalacia reticulata

(2009) Lyann Sim et al.   BIOCHEMISTRY

Facile synthesis of de-O-sulfated salacinols: Revision of the structure of neosalacinol, a potent α-glucosidase inhibitor

(2009) Genzoh Tanabe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Salaprionol and Ponkoranol with Thiosugar Sulfonium Sulfate Structure from Salacia prinoides and a-Glucosidase Inhibitory Activity of Ponkoranol and Kotalanol Desulfate

(2009) Masayuki Yoshikawa et al.   HETEROCYCLES

Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases

(2008) Yasuhiro Minami et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The generalized Born/volume integral implicit solvent model: Estimation of the free energy of hydration using London dispersion instead of atomic surface area

(2008) Paul Labute   JOURNAL OF COMPUTATIONAL CHEMISTRY

α-Glucosidase Inhibitor from Kothala-himbutu (Salacia reticulataWIGHT)

(2008) Sei Ozaki et al.   JOURNAL OF NATURAL PRODUCTS

On the structure of the bioactive constituent from ayurvedic medicine Salacia reticulata: revision of the literature

(2008) Osamu Muraoka et al.   TETRAHEDRON LETTERS