Article
Chemistry, Multidisciplinary
Manash Protim Gogoi, Rajeshwer Vanjari, B. Prabagar, Shengwen Yang, Shubham Dutta, Rajendra K. Mallick, Vincent Gandon, Akhila K. Sahoo
Summary: A novel synthetic reaction is reported in this study, which introduces a sulfide moiety and an allyl group into ynamides to produce highly substituted thioamino-skipped-dienes with broad substrate scope, while maintaining complete atom economy. The reaction can also be extended to the synthesis of selenoamino dienes, providing insights into the reaction mechanism through DFT studies and control experiments.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Milan Pramanik, Ashis Mathuri, Prasenjit Mal
Summary: The study utilized the sulfur oxygen interaction to achieve (Z)-selective anti-Markovnikov vinyl sulfides from thiyl radicals addition to terminal alkynes. DFT calculations indicated that the SMIDLINE HORIZONTAL ELLIPSISO interaction was a result of delocalization of the lone pair of the carbonyl oxygen to the adjacent sigma* orbital of the S atom of C-S.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Organic
Meghan Fragis, Jackson L. Deobald, Srinivas Dharavath, Jeffrey Scott, Jakob Magolan
Summary: This study overcomes the issue of competing redox chemistry between phosphines and sulfoxides, achieving a novel phosphine Pummerer reaction for the synthesis of diverse vinyl sulfides. The method allows for a two-step one-carbon homologation of aldehydes to ketones, offering efficiency and versatility.
Article
Chemistry, Multidisciplinary
Marie-Claire Giel, Andrew S. Barrow, Christopher J. Smedley, William Lewis, John E. Moses
Summary: This study presents a novel and mild method for catalytic Markovnikov hydration of (E)-aryl enynes to corresponding enones using a bench-stable aminium salt, TBPA. The chemoselective and diastereoselective transformation proceeds under neutral metal-free conditions, delivering excellent product yields. The utility of this transformation is demonstrated through the synthesis of biologically important (E)-3-styrylisocoumarins, including a formal synthesis of achlisocoumarin III.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Applied
Nikolai A. Sitte, Francesca Ghiringhelli, Grigory A. Shevchenko, Frank Rominger, A. Stephen K. Hashmi, Thomas Schaub
Summary: A copper(I)/phosphine system that catalyzes the alkynylation of formaldehyde with acetylene or terminal alkynes is reported. The catalyst consisting of <1 mol% copper(I) phenylacetylide and a trialkyl bisphosphine ligand shows high selectivity towards the formation of propargyl alcohol. The biphasic water/toluene reaction mixture allows for the separation of targeted products and catalyst recycling.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Chemistry, Applied
Xinglin Wang, Yuanyuan Li, Zhaohui Li
Summary: This study demonstrates the use of Ir2S3/ZnIn2S4 nanocomposites to promote the hydrothiolations of alkenes and alkynes, with improved efficiency on the photogeneration of thiyl radicals. The findings provide guidance for the design and development of photocatalytic systems for light induced organic syntheses.
CHINESE JOURNAL OF CATALYSIS
(2021)
Article
Chemistry, Physical
Son H. Doan, Binh Khanh Mai, Thanh Vinh Nguyen
Summary: Multiboronate compounds are used as synthetic building blocks for complex organic architectures via C-B bond cross-coupling chemistry. However, there are still challenges such as low efficiency, poor selectivity, and narrow substrate and catalyst scopes in this research area.
Article
Chemistry, Multidisciplinary
Jieping Chen, Xuzhong Shen, Zhan Lu
Summary: A cobalt-catalyzed Markovnikov-type hydroboration method has been developed for the synthesis of alpha-alkenyl boronates with good regioselectivity and atom economy. The new ligand used with the cobalt hydride catalyst facilitates the selective insertion of terminal alkynes into metal hydride bonds. This protocol shows excellent tolerance to functional groups and delivers valuable alkene derivatives efficiently.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Applied
Dean D. Roberts, Mark G. McLaughlin
Summary: We have conducted the first study on the use of platinum complexes in the hydrostannylation of terminal alkynes. Among several platinum complexes screened, PtCl2/XPhos exhibited the highest selectivity for beta-(E)-vinyl stannane. The catalyst system not only provided superior selectivity compared to palladium catalysis but also allowed for a telescoped hydrometallation/cross-coupling sequence, eliminating the need for excessive manipulation or purification of the intermediate stannane.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Yang Yang, Dong Xing
Summary: In this study, an iridium-catalyzed branched-selective hydroacylation of 1-aryl 1,3-dienes with salicylaldehydes was successfully conducted under mild conditions without the need for phosphine ligands. The protocol yielded a series of alpha-branched beta,gamma-unsaturated o-hydroxyacetophenones with biological potentials in high efficiency and excellent regioselectivities. Exclusive linear-selective hydroacylation products were obtained when simple 1,3-butadiene or isoprene were used instead of 1-aryl 1,3-dienes.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Katarina Stefkova, Matthew J. Heard, Ayan Dasgupta, Rebecca L. Melen
Summary: Triarylboranes have garnered significant attention as catalysts for C-C bond forming reactions due to their remarkable catalytic activities. In this study, the B(C6F5)(3) catalyzed cyclopropenation of arylacetylenes using donor-acceptor diazoesters has been successfully developed, resulting in the synthesis of a wide variety of functionalized cyclopropenes in good to excellent yields.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Stefan Weber, Luis F. Veiros, Karl Kirchner
Summary: Efficient manganese-catalyzed dimerization of terminal alkynes to produce 1,3-enynes is achieved in this study. The reaction is atom economic, utilizing an inexpensive catalyst with high efficiency and selectivity.
Article
Chemistry, Organic
Danqing Ji, Xingwei Li
Summary: A rhodium-catalyzed C-H bond activation of propargyl carbamates with benzamides has resulted in the decarboxylative annulation, leading to the synthesis of two distinct classes of heterocycles in high efficiency and selectivity under substrate control. This protocol provides a direct synthetic method for the preparation of functionalized 1,8-naphthyridines and isoindolinones.
Article
Chemistry, Organic
Shenghai Guo, Ziyi Zhang, Yuanqing Zhu, Zhaotong Wei, Xinying Zhang, Xuesen Fan
Summary: A practical and selective method for the synthesis of novel isoquinolone-containing spirocyclic and oxepine-fused polycyclic skeletons through rhodium-catalyzed oxidative [4 + 1] spiroannulation or formal [4 + 3] annulation reactions has been reported. The protocol exhibits wide substrate scope, simple operation procedures, and excellent regioselectivity. The obtained products also hold potential applications in further transformations.
ORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Multidisciplinary
Diksha Parmar, Tamanna Sharma, Akhilesh K. K. Sharma, Upendra Sharma
Summary: A concise method for Rh(iii)-catalyzed, directing-group-assisted C-H/C-H cross-coupling of N-heterocycles (quinolines, indolines, indoles, pyridines, pyrimidines, pyrazoles) with other heteroarenes (benzoxazoles, benzofurans, and thiophenes) is disclosed for the synthesis of unsymmetrical heterobiaryl compounds in good to excellent yields. A plausible catalytic cycle has been delineated based on experimental and computational mechanistic studies.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Nimmakuri Rajesh, Dipak Prajapati
CHEMICAL COMMUNICATIONS
(2015)
Article
Chemistry, Organic
Nimmakuri Rajesh, Dipak Prajapati
ORGANIC & BIOMOLECULAR CHEMISTRY
(2015)
Article
Chemistry, Multidisciplinary
Yuvaraj Dommaraju, Somadrita Borthakur, Nimmakuri Rajesh, Dipak Prajapati
Article
Chemistry, Organic
Nimmakuri Rajesh, Nagaraju Barsu, Basker Sundararaju
TETRAHEDRON LETTERS
(2018)
Article
Chemistry, Organic
Nimmakuri Rajesh, Basker Sundararaju
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Chemistry, Organic
Nimmakuri Rajesh, Rupam Sarma, Dipak Prajapati
Article
Chemistry, Multidisciplinary
Nimmakuri Rajesh, Dipak Prajapati
Article
Chemistry, Multidisciplinary
Nimmakuri Rajesh, Rupam Sarma, Dipak Prajapati
Article
Chemistry, Multidisciplinary
Malay Sen, Nimmakuri Rajesh, Balakumar Emayavaramban, J. Richard Premkumar, Basker Sundararaju
CHEMISTRY-A EUROPEAN JOURNAL
(2018)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)