期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 88, 页码 10835-10837出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc36293g
关键词
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资金
- Japan Society for the Promotion of Science for Young Scientists
- Ministry of Education, Culture, Sports, Science and Technology of Japan [KAKENHI 19201046, 24710256]
- Grants-in-Aid for Scientific Research [24710256, 11J07372] Funding Source: KAKEN
Toward new biotechnology by genetic alphabet expansion, we developed an efficient site-specific labeling method for large RNA molecules. The combination of unnatural base pair transcription and post-transcriptional modification by click chemistry enables simple RNA labeling with a wide variety of functional groups at desired positions, in a one-pot reaction.
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