期刊
CHEMICAL COMMUNICATIONS
卷 48, 期 22, 页码 2803-2805出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc17339e
关键词
-
资金
- Ministry of Education, Culture, Sports, Science and Technology, Japan [B01]
- Grants-in-Aid for Scientific Research [22550092] Funding Source: KAKEN
The enantioselective synthesis of a-hydroxy esters by ruthenium-catalyzed 1,2-addition of arylboronic acids to tert-butyl glyoxylate is described. The use of RuCl2(PPh3)(3) with (R, R)-Me-BIPAM gave optically active mandelic acids of up to 99% ee. Addition of a fluoride salt such as potassium fluoride (KF) or caesium fluoride (CsF) was effective for achieving high enantioselectivities.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据