Article
Chemistry, Organic
Timothy J. Paris, Chris Schwartz, Eric Sundall, Rachel Willand-Charnley
Summary: A rapid one-step synthesis of alpha-ketoacetals was achieved via electrophilic etherification, obtaining different yields of products using specific substrates and peroxyacetals. The method is applicable for C-O bond formation at tertiary carbons, with the alpha-OCH3 group playing a critical role in ensuring product formation.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Te-Sheng Chang, Chien-Min Chiang, Tzi-Yuan Wang, Yu-Li Tsai, Yu-Wei Wu, Huei-Ju Ting, Jiumn-Yih Wu
Summary: Ganoderma lucidum is a medicinal fungus with triterpenoids as its main bioactive compounds. Through enzymatic reactions, various triterpenoid glycosides can be synthesized, which have higher aqueous solubility and potential applications in future drug development.
Article
Chemistry, Organic
Moustafa E. El-Araby, Abdelsattar M. E. Omar
Summary: The study describes a reaction that leads to highly substituted piperazinone derivatives in a single step, providing a new pathway for the preparation of diverse compounds. The structure and mechanism of the reaction were confirmed through extensive spectral analyses and mass spectrometry, and it has the potential to serve as a rapid route to diversified heterocycles.
JOURNAL OF HETEROCYCLIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Jiumn-Yih Wu, Tzi-Yuan Wang, Hsiou-Yu Ding, Yun-Rong Zhang, Shu-Yuan Lin, Te-Sheng Chang
Summary: Researchers found that an enzyme from Bacillus thuringiensis could convert vitexin into two new compounds with higher aqueous solubility, which enhances the potential applications of vitexin.
Article
Materials Science, Multidisciplinary
Rahul Singh, Ragini Raj Singh
Summary: This article introduces a new method for synthesizing zinc sulfo-oxide (ZnSO) and highlights its potential applications in solar cells and lithium-ion batteries.
Article
Chemistry, Organic
Yuan Li, Jiamei Shen, Yawei Shen, Yanfeng Li, Kai Luo, Lei Wu
Summary: A novel and efficient reaction method using NaOH as a base has been developed for the tandem S(N)2 nucleophilic substitution/Dieckmann condensation reaction of a-iodomethyl phosphine oxide with methyl thiosalicylate derivatives. This method enables the rapid synthesis of 2-phosphonyl-3-hydroxybenzo[b]thiophene derivatives under simple conditions. Furthermore, several new phosphonyl-substituted benzo[b]thiophenes were obtained from the resultant 2-phosphonyl-3-hydroxybenzo[b]thiophenes.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Tomas Vieira de Castro, David M. M. Huang, Christopher J. J. Sumby, Andrew L. L. Lawrence, Jonathan H. H. George
Summary: A concise method for the synthesis of a stereochemically complex compound, peshawaraquinone, from an achiral precursor, dehydro-alpha-lapachone, via unsymmetrical dimerization is reported. The formation of the compound involves reversible oxa-6 pi-electrocyclizations and base-catalyzed dimerization, resulting in the formation of six stereocenters through an intramolecular (3 + 2) cycloaddition. Combining the generation and in situ dimerization of dehydro-alpha-lapachone allows a one-step total synthesis of peshawaraquinone from lawsone and prenal.
Article
Chemistry, Physical
Syed Ibrahim Gnani Peer Mohamed, Tan Zhang, Zhen Jiang, Andrew M. Rappe, Siamak Nejati
Summary: Ionic covalent organic frameworks (iCOFs) have attractive properties and can be used for ion transport, energy storage, and metal sorption. However, the current synthetic methods are limited. In this study, an iCOF was synthesized via a single-step reaction, and it was found that the framework was predominantly assembled into staggered configurations.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Applied
Xiaoquan Li, Fuping Bian, Jiwen Hu, Shi Li, Xuefeng Gui, Shudong Lin
Summary: In this study, three multifunctional silicone acrylate prepolymers were synthesized via one-step hydrosilylation. The prepolymers exhibited high UV curing activity, transparency, hydrophobicity, and excellent heat resistance, suggesting their potential application as UV-curable anti-smudge coatings.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Materials Science, Multidisciplinary
Daxian Zuo, Cuiping Wang, Jiajia Han, Qinghao Han, Yanan Hu, Junwei Wu, Huajun Qiu, Qian Zhang, Xingjun Liu
Summary: This study demonstrates a one-step synthesis strategy for the core-shell manganese hexacyanoferrate and investigates its formation mechanism. The core-shell structure of the material exhibits superior electrochemical performance, with higher discharge capacity and better cycling stability compared to materials prepared by traditional methods.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Physical
Yuping Xu, Yunzi Xin, Takashi Shirai
Summary: Visible photoluminescent silicon nanocrystals capped with hydrophobic surface were successfully synthesized using a novel one-step bottom-up approach. The synthesized Si NCs have an average size of 3.4 nm and exhibit visible photoluminescence with a high absolute quantum yield of 17%, possibly due to the efficient hydrophobic surface capping on the Si NCs.
COLLOID AND INTERFACE SCIENCE COMMUNICATIONS
(2021)
Article
Biochemical Research Methods
Chang Soo Kim, Dmitry Nevozhay, Rebeca Romero Aburto, Ashok Pehere, Lan Pang, Rebecca Dillard, Ziqiu Wang, Clayton Smith, Kelsey Boitnott Mathieu, Marie Zhang, John D. Hazle, Robert C. Bast, Konstantin Sokolov
Summary: Lipid-based formulations, combined with magnetic nanoparticles, have shown great potential in biomedical applications such as drug delivery and therapy. In this study, we developed a simplified method to synthesize drug-loaded magnetic multimicelle aggregates and achieved molecular targeting through antibody conjugation.
BIOCONJUGATE CHEMISTRY
(2022)
Article
Materials Science, Paper & Wood
Fengxiu Zhang, Ying Liao, Yu Chen, Yi Lu, Caiyan Wan, Guangxian Zhang
Summary: The novel N-P ammonium salt APGDPE flame retardant was synthesized and grafted onto cotton fabric to enhance flame retardancy and durability. Testing results of the treated cotton fabric showed improved thermal stability, flame retardant properties, and reduced flammable volatile gas emissions compared to control cotton fabric.
Article
Chemistry, Medicinal
Yuchen Tan, Han Hu, Wenjian Zhu, Tao Wang, Tian Gao, Hongqi Wang, Jian Chen, Jinyi Xu, Shengtao Xu, Huajian Zhu
Summary: A series of novel dihydroquinolin-4(1H)-one derivatives were synthesized and evaluated for their anticancer activity. The most potent compound 6t showed remarkable antiproliferative activities, inhibited tubulin polymerization, and inhibited tumor growth in vitro and in vivo.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Amaneh Mosaffaeirad, Masoud Mokhtary, Mohammad Nikpassand
Summary: A new efficient process for synthesizing aryldiazenyl-2-hydroxybenzylidenecyanoarylhydrazide analogs was developed using a heterogeneous catalyst PVPP-p-TSA in ethanol. The products were characterized by various spectroscopic techniques. The catalyst exhibited good reusability without significant loss of stability or structural change.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Biochemistry & Molecular Biology
Ben A. Wagstaff, Martin Rejzek, Thomas Pesnot, Lauren M. Tedaldi, Lorenzo Caputi, Ellis C. O'Neill, Stefano Benini, Gerd K. Wagner, Robert A. Field
CARBOHYDRATE RESEARCH
(2015)
Article
Biochemistry & Molecular Biology
Gerd K. Wagner, Thomas Pesnot, Monica M. Palcic, Rene Jorgensen
JOURNAL OF BIOLOGICAL CHEMISTRY
(2015)
Article
Chemistry, Organic
Giulia Pergolizzi, Marco M. D. Cominetti, Julea N. Butt, Robert A. Field, Richard P. Bowater, Gerd K. Wagner
ORGANIC & BIOMOLECULAR CHEMISTRY
(2015)
Review
Biochemistry & Molecular Biology
Giulia Pergolizzi, Gerd K. Wagner, Richard P. Bowater
BIOSCIENCE REPORTS
(2016)
Article
Chemistry, Multidisciplinary
Jingqian Jiang, Varsha Kanabar, Beatriz Padilla, Francis Man, Simon C. Pitchford, Clive P. Page, Gerd K. Wagner
CHEMICAL COMMUNICATIONS
(2016)
Article
Biochemistry & Molecular Biology
Varsha Kanabar, Lauren Tedaldi, Jingqian Jiang, Xiaodan Nie, Irina Panina, Karine Descroix, Francis Man, Simon C. Pitchford, Clive P. Page, Gerd K. Wagner
Editorial Material
Chemistry, Medicinal
Gerd K. Wagner
FUTURE MEDICINAL CHEMISTRY
(2017)
Article
Biochemistry & Molecular Biology
Shonoi A. Ming, Ebony Cottman-Thomas, Natalee C. Black, Yi Chen, Vamsee Veeramachineni, Dwight C. Peterson, Xi Chen, Lauren M. Tedaldi, Gerd K. Wagner, Chao Cai, Robert J. Linhardt, Willie F. Vann
Article
Biochemistry & Molecular Biology
Yong Xu, Jon Cuccui, Carmen Denman, Tripty Maharjan, Brendan W. Wren, Gerd K. Wagner
BIOORGANIC & MEDICINAL CHEMISTRY
(2018)
Article
Allergy
Silvia Crescioli, Giulia Chiaruttini, Silvia Mele, Kristina M. Ilieva, Giulia Pellizzari, Daniel I. R. Spencer, Richard A. Gardner, Katie E. Lacy, James F. Spicer, Andrew N. J. Tutt, Gerd K. Wagner, Sophia N. Karagiannis
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Masaki Ema, Yong Xu, Sebastian Gehrke, Gerd K. Wagner
Review
Biochemistry & Molecular Biology
Alice Collier, Gerd K. Wagner
CARBOHYDRATE RESEARCH
(2017)
Review
Biochemistry & Molecular Biology
Jingqian Jiang, Gerd K. Wagner
CARBOHYDRATE RESEARCH
(2017)
Article
Biochemistry & Molecular Biology
Yong Xu, Ruth Smith, Mirella Vivoli, Masaki Ema, Niina Goos, Sebastian Gehrke, Nicholas J. Harmer, Gerd K. Wagner
BIOORGANIC & MEDICINAL CHEMISTRY
(2017)
Meeting Abstract
Biochemistry & Molecular Biology
Ebony Cottman-Thomas, Shonoi Ming, Lauren Tedaldi, Gerd Wagner, Yi Chen, Xi Chen, Cao Cai, Robert Linhardt, Willie Vann
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
