Palladium-catalyzed asymmetric synthesis of 2-pyrrolidinones with a quaternary carbon stereocenter

Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors

(2012) Xiongyu Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Stereoselective Synthesis of (S)-3-(Methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile

(2012) Manjinder S. Lall et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Construction of Pyrrolidines by Palladium-Catalyzed Asymmetric [3 + 2] Cycloaddition of Trimethylenemethane with Imines

(2012) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anti-Selective Direct Catalytic Asymmetric Aldol Reaction of Thiolactams

(2012) Devarajulu Sureshkumar et al.   ORGANIC LETTERS

Monosubstituted γ-lactam and conformationally constrained 1,3-diaminopropan-2-ol transition-state isostere inhibitors of β-secretase (BACE)

(2011) Kenneth M. Boy et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Guiding the nitrogen nucleophile to the middle: palladium-catalyzed decarboxylative cyclopropanation of 2-alkylidenetrimethylene carbonates with isocyanates

(2011) Ryo Shintani et al.   CHEMICAL COMMUNICATIONS

Development of an Asymmetric Trimethylenemethane Cycloaddition Reaction: Application in the Enantioselective Synthesis of Highly Substituted Carbocycles

(2011) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Investigation of the Palladium-Catalyzed Decarboxylative Cyclization of γ-Methylidene-δ-valerolactones with Isocyanates: Kinetic Studies and Origin of the Site Selectivity in the Nucleophilic Attack at a (π-Allyl)palladium

(2010) Ryo Shintani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The spirocyclopropyl moiety as a methyl surrogate in the structure of l-fucosidase and l-rhamnosidase inhibitors

(2009) Morwenna S.M. Pearson et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Highly Diastereo- and Enantioselective Pd-Catalyzed Cyclopropanation of Acyclic Amides with Substituted Allyl Carbonates

(2009) Wei Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Asymmetric Decarboxylative Lactamization of γ-Methylidene-δ-valerolactones with Isocyanates: Conversion of Racemic Lactones to Enantioenriched Lactams

(2008) Ryo Shintani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY