Review
Chemistry, Multidisciplinary
Jiating Xu, Jun Wang, Jin Ye, Jiao Jiao, Zhiguo Liu, Chunjian Zhao, Bin Li, Yujie Fu
Summary: Metal-coordinated supramolecular nanoassemblies have unique physicochemical properties that bridge the boundary between traditional inorganic and organic materials, making them promising for cancer theranostics. By tailoring the structural components, multifunctional theranostic nanomedicines can be constructed to modulate the tumor microenvironment and enhance tumor accumulation. The advancements in design and fabrication, as well as the prospects and challenges of metal-coordinated supramolecular self-assemblies for technical advances and clinical translation, are discussed.
Article
Nanoscience & Nanotechnology
Indulekha Mukkatt, Anjali Nirmala, Nayan Dev Madhavan, Sreejith Shankar, Biswapriya Deb, Ayyappanpillai Ajayaghosh
Summary: The study designed three tetraterpyridine ligands with variations in their core architecture to create spray-coated electrochromic assemblies of iron(II)-based metallosupramolecular polymer network films. These assemblies exhibited high coloration efficiencies and optical contrast, suitable for electrochromic devices. The ligand-structure induced differential metal coordination led to porosity and spectroelectrochemical diversification, enabling the creation of electrochromic patterns and images through a simple spray-coating technique.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Junyang Huang, Tamas Foldes, Jade A. McCune, David D. Xu, Bart de Nijs, Rohit Chikkaraddy, Sean M. Collins, Edina Rosta, Jeremy J. Baumberg, Oren A. Scherman, Kamil Sokolowski
Summary: The study demonstrates the use of semiconductor nanocrystals to control the self-limiting aggregation of larger nanostructures, leading to stable photoactive hybrids for photocatalysis. Real-time monitoring of electron transfer processes and catalysis under irreversible conditions is now possible through this approach.
NATURE NANOTECHNOLOGY
(2021)
Article
Chemistry, Organic
Dorian Dupommier, Michel Boisbrun, Gerald Monard, Corinne Comoy
Summary: By exploring a method for the functionalization of BTZD scaffold, we have opened up a new chemical space around BTZD. Key intermediates, 6-chloro- and 6-formyl BTZD, were obtained and used in Pd catalyzed cross-coupling or Wittig olefination reactions. Various substituents were successfully introduced onto the vinylic position of BTZD, and the stereochemistry of benzylidene derivatives was elucidated through a combined DFT/NMR study.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Biophysics
Shuai Cao, Le Zhou, Chang Liu, Huacheng Zhang, Yuxin Zhao, Yanli Zhao
Summary: The ingenious design and synthesis of novel macrocycles brought renewed vigor to supramolecular chemistry in the past decade. Pillarene and pillararene-based functional materials have seen rapid growth in electrochemical studies due to their unique structures and physiochemical properties. Challenges and future developments in this field have been discussed, providing a solid foundation for further bioelectrochemical applications of pillararene systems.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Engineering, Biomedical
Sean H. Kelly, Emmanuel E. Opolot, Yaoying Wu, Benjamin Cossette, Ajay K. Varadhan, Joel H. Collier
Summary: The SIMPL tablet vaccine, which can be administered sublingually, shows promising results in raising antibody responses against various epitopes, including a model epitope from ovalbumin and a clinically relevant epitope from Mycobacterium tuberculosis. The heat-stable feature of this vaccine is particularly advantageous for global distribution and equity in vaccine coverage.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Chandrakanta Guchhait, Vembanan Suriyaa, Nihar Sahu, Sovik Dey Sarkar, Bimalendu Adhikari
Summary: Ferrocene has potential applications in various fields such as ligand design, catalysis, analytical chemistry, biological chemistry, medicinal chemistry, and materials chemistry. It can be used as a building block in supramolecular chemistry, forming stable host-guest complexes with different macrocyclic host molecules. The unique properties of ferrocene make it suitable for the development of smart molecular receptors, metal-organic assemblies, supramolecular polymers, gels, and metal nanoparticle assemblies.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Zhehui Weng, Xiaohua Zhou, Jie Ling, Pengzhi Xiang, Yao Huang, Haidong Ju, Shengchun Chen, Zhihui Zhang
Summary: Five new coordination assemblies of substituted zinc(II) isophthalates and H(2)pbbp linkers have been synthesized under hydrothermal conditions, exhibiting different layer structures and supramolecular networks. The properties of these compounds, including thermal stability, powder X-ray diffractions, infrared spectra and luminescence, have been investigated.
JOURNAL OF SOLID STATE CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Shanyuan Zhong, Lingyun Zhu, Shuai Wu, Yuanming Li, Meijin Lin
Summary: This review provides a comprehensive summary of the synthesis, optical properties, host-guest chemistry, and applications of donor-acceptor conjugated macrocycles, focusing on recent progress in the field of synthetic methods and their use in chemical sensors, bioimaging, and photoelectronic devices.
CHINESE CHEMICAL LETTERS
(2023)
Article
Engineering, Biomedical
Nicole L. Votaw, Lauren Collier, Elizabeth J. Curvino, Yaoying Wu, Chelsea N. Fries, Madison T. Ojeda, Joel H. Collier
Summary: This study introduced a self-assembling randomized polypeptide nanomaterial capable of inducing strong Type 2/TH2/IL-4 immune responses, with potential applications ranging from vaccination to tissue repair. The modified peptides showed improved antigen presenting cell uptake, strong B-cell and T-cell epitopes, increased IL-4 production by T cells, extended nanofiber residence time, minimal swelling in footpad injections, and decreased overall T cell expansion compared to unmodified nanofibers, suggesting a TH2 T-cell response with minimal inflammation.
Article
Chemistry, Organic
Kun Wang, Yan-Jiang Yu, Xiao-Qing Wang, Yu-Qing Bai, Mu-Wang Chen, Yong-Gui Zhou
Summary: In this study, a palladium-catalyzed asymmetric hydrogenation of unprotected 3-substituted indoles was developed, providing a series of 3-substituted indolines in high yields with good enantioselectivity (<= 94.4:5.6 er). The bulky bisphosphine ligand played a crucial role in controlling the enantioselectivity. In addition, gram-scale hydrogenation experiments and product derivatizations were successfully conducted.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Ana Gutierrez-Blanco, Christian Dobbe, Alexander Hepp, Constantin G. Daniliuc, Macarena Poyatos, F. Ekkehardt Hahn, Eduardo Peris
Summary: Three metallosupramolecular assemblies consisting of NHC ligands and silver atoms have been prepared. Each assembly shows different structures and reactivities, including the formation of cyclobutane rings and the generation of different isomers.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Review
Chemistry, Inorganic & Nuclear
Qin-Yu Zhu, Jie Dai
Summary: Titanium oxo-clusters can serve as a molecular model of nano TiO2 for theoretical and experimental studies, and also function as single-source precursors for TiO materials. They show promising applications in solar energy harvesting, photoelectric sensing, and fluorescent displaying, offering new perspectives for advanced functional materials.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Chemistry, Multidisciplinary
Dihua Dai, Jie Yang, Ying-Wei Yang
Summary: This minireview summarizes the recent progress in superior detection systems based on supramolecular assemblies with AIE features. It provides relevant researchers with new ideas for constructing new AIE-based supramolecular materials with advanced architectures for effective sensing and detection.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Leyong Zhou, Changyin Yang, Weitao Dou, Tongxia Jin, Haibo Yang, Lin Xu
Summary: This review summarizes the application of micro/nanofluidic techniques in constructing supramolecular assemblies of different scales, and highlights the advantages of these techniques over conventional synthesis methods. Furthermore, it emphasizes the potential of micro/nanofluidic systems in improving our understanding of supramolecular self-assembly processes.
CHINESE CHEMICAL LETTERS
(2024)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)