期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 8, 页码 2348-2350出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04319b
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资金
- National Natural Science Foundation of China [20972083]
- Ministry of Science and Technology of China [2009ZX09501-004]
- Key Subject Foundation from Beijing Department of Education [XK100030514]
A simple, practical and efficient copper-catalyzed method for synthesis of aromatic carboxylic acids has been developed. The protocol uses inexpensive CuI/L-proline as the catalyst/ligand, and readily available aryl halides and malononitrile as the starting materials, and the corresponding aromatic carboxylic acids were obtained in moderate to good yields. The method is of tolerance towards functional groups in the substrates.
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