Article
Biochemistry & Molecular Biology
Maria E. Perez, Javier E. Durantini, Eugenia Reynoso, Maria G. Alvarez, Maria E. Milanesio, Edgardo N. Durantini
Summary: New porphyrin-Schiff base conjugates containing one (6) and two (7) basic amino groups were synthesized, allowing easier access to porphyrins substituted with positive charge precursor groups in aqueous media. These compounds showed red fluorescence emission and were able to photo-oxidize amino acids, with enhanced photodynamic inactivation capacity when combined with iodide anions. The presence of basic aliphatic amino groups in these porphyrins provided an amphiphilic character, improving their interaction with cell walls and photocytotoxic activity against microorganisms.
Article
Biochemistry & Molecular Biology
Akira Shinohara, Hideyuki Shinmori
Summary: Here, we present a switching method for singlet oxygen (O-1(2)) generation by adsorption/desorption of porphyrins to gold nanoparticles driven by sulfide compounds. The generation of O-1(2) by photosensitization is effectively suppressed by the gold nanoparticles and can be restored through a sulfide ligand exchange reaction. The on/off ratio of O-1(2) quantum yield (phi(Delta)) reached 7.4. By examining various incoming sulfide compounds, it was found that the ligand exchange reaction on the gold nanoparticle surface could be thermodynamically or kinetically controlled. The remaining gold nanoparticles in the system still suppress the generation of O-1(2), which can be precipitated out simultaneously with porphyrin desorption by the proper polarity choice of the incoming sulfide to restore the O-1(2) generation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Multidisciplinary
Patrycja Talarska, Maciej Boruczkowski, Jakub Zurawski
Summary: Silver and gold nanoparticles are widely used in various household products, raising concerns about their potential impact. Research is focusing on the effects of nanoparticles on cell function and environmentally friendly alternatives to chemically synthesized nanoparticles.
Article
Biophysics
Sophie Shin Lu, You -Ren Lai, Li-Hsing Hsiao, Hsin-Yi Huang, Ya-Hui Tsai, Yun Chen, Steven S. -S. Wang, Yi-Chun Yeh, Shen-Long Tsai
Summary: This study investigates the influence of amino acid-modified silver nanoparticles on amyloid fibril formation. The results show that the modified nanoparticles can suppress amyloid fibrillogenesis and induce structural changes in proteins.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Ana C. Quevedo, Iseult Lynch, Eugenia Valsami-Jones
Summary: Evaluation of uptake mechanisms of silver nanoparticles of different sizes in zebrafish cells revealed size- and time-dependent uptake patterns and showed strong associations with endocytosis pathways and autophagy induction. These findings provide insights into the cellular processes of nanoparticle uptake and suggest potential implications for risk assessment and nanomaterial development.
Article
Pharmacology & Pharmacy
J. G. B. De Marchi, R. Ce, G. Onzi, A. C. S. Alves, N. Santarem, A. Cordeiro da Silva, A. R. Pohlmann, S. S. Guterres, A. J. Ribeiro
Summary: This study aims to improve the absorption of nanoparticle formulation by functionalizing its surface with immunoglobulin G. The functionalized nanoparticles showed adequate size and good entrapment efficiency, and led to a desirable increase in insulin release time. Interactions of nanoparticle components were proven through differential scanning calorimetry, infrared spectroscopy, and paper chromatography.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Chemistry, Analytical
Lu Wang, Lan Zhang, Baoxian Ye
Summary: An efficient method for in-situ assembly of silver nanoparticles on glycine functionalized graphene has been proposed, which only requires a simple hydrothermal reaction. The microstructure of the material was characterized and the electrochemical sensor prepared showed improved performance compared to the control samples. The electrochemical reaction mechanism and quantitative analysis of bergenin were studied, and the analytical availability of the sensor was demonstrated in real-life samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Tawfik A. Saleh, Asma M. Elsharif, Osamah A. Bin-Dahman
Summary: Carbon nanotubes were functionalized with amine groups and conjugated with prophyrine derivatives to increase active sites. Compound 3 showed better adsorption efficiency for methylene blue at different pH values, achieving high efficiency when the adsorbent dosage increased. The adsorption mechanism involved non-electrostatic and electrostatic interactions, making the material effective for simultaneous adsorption of MB and toxic metal ions.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
Jinzhu Zhang, Wei Hua, Xiaoye Zhou, Chen Zhou, Yemei Wang, Xianzhi Chai, Shasha Sun, Fenfen Zheng
Summary: In this study, an ultra-stable platform based on silver nanoparticles (AgNPs) was developed for real-time in vivo plasma biothiol sensing through a urinalysis method. The platform was created by conjugating a renal-clearable organic dye, TAMRA, onto glutathione-coated AgNPs as a protective surface layer. The platform exhibited good stability in aqueous solution and showed significant fluorescence enhancement and spectral red shift upon interactions with biothiols. The successful imaging of mouse bladder and subsequent analysis of urine samples demonstrated the efficiency of the AgNPs-based platform for plasma biothiol sensing through urinalysis. This approach offers a practical pathway for diagnosing biothiol-associated diseases in clinics and enables further in vivo monitoring and detection through the synergistic effects of dyes and AgNPs.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Energy & Fuels
Rajesh Pandiyan, Revathi Rajagopal
Summary: The discharge of dye from the textile industry into the water is a major environmental problem. This study focuses on using synthesized silver and lead nanoparticles to treat wastewater containing dye. The treated water can be further purified for agricultural and domestic purposes.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Chemistry, Physical
Rahim Ghadari, Alireza Sabri, Paria-Sadat Saei, Fantai Kong, Yousef Mohammadzadeh, Emre Guzel
Summary: The study utilized surface plasmon resonance of silver nanoparticles to enhance porphyrin-sensitized solar cells, investigating the impact of different substituents on porphyrins and the electronic properties of porphyrin-AgNPs systems. The results showed that the nature of substituents plays a significant role in the performance of the systems.
JOURNAL OF POWER SOURCES
(2021)
Article
Materials Science, Multidisciplinary
Jake M. Evans, Kyra S. Lee, Ellen X. Yan, Annelise C. Thompson, Maureen B. Morla, Madeline C. Meier, Zachary P. Ifkovits, Azhar I. Carim, Nathan S. Lewis
Summary: Chemically functionalized MoS2 sensors exhibited high sensitivity to both polar and nonpolar VOCs, and retained over 70% of their initial responsiveness after at least 72 hours in air.
ACS MATERIALS LETTERS
(2022)
Article
Materials Science, Multidisciplinary
Jake M. Evans, Kyra S. Lee, Ellen X. Yan, Annelise C. Thompson, Maureen B. Morla, Madeline C. Meier, Zachary P. Ifkovits, Azhar I. Carim, Nathan S. Lewis
Summary: In this study, chemically functionalized MoS2 was successfully transformed into a chemically sensitive vapor sensor with high sensitivity for detecting both polar and nonpolar VOCs.
ACS MATERIALS LETTERS
(2022)
Article
Materials Science, Biomaterials
Wei Zhang, Lu Xu, Xianbin Zhang, Peng Gong, Xiyu Wang, Zhiying Xu, Ganyu Nie, Lu Xu
Summary: This study synthesized a nanohybrid with a core of mesoporous silica nanorods and shell of folate-functionalized zeolite imidazole framework, which showed potential for improving chemotherapy and phototherapy treatment. The nanohybrid demonstrated a moderate photothermal conversion efficiency and the ability to release 1O2, leading to enhanced therapeutic effects against cancer.
BIOMATERIALS SCIENCE
(2023)
Article
Materials Science, Biomaterials
Wei Zhang, Lu Chen, Xianbin Zhang, Peng Gong, Xiyu Wang, Zhiying Xu, Ganyu Nie, Lu Xu
Summary: A nanohybrid with a core of mesoporous silica nanorods and shell of folate-functionalized zeolite imidazole framework was synthesized, and chemotherapeutic drug and photosensitive agent were loaded to construct a smart delivery system. The nanohybrid showed good photothermal conversion efficiency and the ability to release singlet oxygen, thereby improving the antitumor therapy.
BIOMATERIALS SCIENCE
(2023)
Article
Polymer Science
Dhruvi Patel, Debes Ray, Ketan Kuperkar, Haridas Pal, Vinod K. Aswal, Pratap Bahadur
POLYMER INTERNATIONAL
(2020)
Article
Chemistry, Physical
Mhejabeen Sayed, Jyoti Balayan, Prabhat K. Singh, Haridas Pal
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2020)
Article
Chemistry, Physical
Shreya Sinha, Poojan Milan Gharat, Haridas Pal, Sharmistha Dutta Choudhury
JOURNAL OF MOLECULAR LIQUIDS
(2020)
Article
Chemistry, Physical
Goutam Chakraborty, Prabhat K. Singh, Haridas Pal
Summary: This study investigates the host-assisted aggregation of an anionic organic probe molecule in the presence of a cationic cyclodextrin derivative, revealing that electrostatic interactions play a key role in the formation of the complex. The monomer-aggregate equilibrium in the system is highly sensitive to external stimuli such as temperature and pH.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Papu Samanta, Sharmistha Dutta Choudhury, Haridas Pal
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2020)
Article
Chemistry, Analytical
Goutam Chakraborty, Alok K. Ray, Prabhat K. Singh, Haridas Pal
Summary: This study presents a novel fluorescence-based method for selective detection and quantification of the common milk allergen beta-LG, demonstrating high sensitivity, selectivity, fast response, and ease of operation. The method utilizes LDS-798 as a fluorogenic probe and achieves a significant fluorescence enhancement upon binding with beta-LG, making it more advantageous than other techniques commonly used for beta-LG quantification. Additionally, the applicability of the probe for quantification of beta-LG in real milk samples has been successfully validated.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
P. R. Ipte, Abhishek Sharma, H. Pal, A. K. Satpati
Summary: The study revealed a good interaction between Cf and dsDNA, forming a stable complex in solution through electrostatic interaction and intercalative binding. The presence of Cf led to the condensation of dsDNA, facilitated by electrostatic interaction and specific functional group interactions.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Goutam Chakraborty, Manoj K. Choudhary, Mahesh Sundararajan, Alok K. Ray, Soumyaditya Mula, Haridas Pal
Summary: The study investigates the interaction between a molecular rotor-based BODIPY dye and a versatile macrocyclic molecule CB7 using various techniques, revealing a significant fluorescence enhancement, reduced structural flexibility, and formation of 1:1 and 1:2 dye-to-host complexes. The potential of the system in different stimuli-responsive sensor applications is also explored by examining its response to changing temperature.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Chemistry, Physical
Goutam Chakraborty, Jotiram N. Malegaonkar, Sidhanath Bhosale, Prabhat K. Singh, Haridas Pal
Summary: Aggregation-induced emission (AIE) of fluorogenic dyes provides various opportunities in smart materials, fluorescence sensing, bioimaging, and molecular electronics. The enhancement of AIE in the SuTPE-AβCD system is achieved through supramolecularly assisted dye aggregation, showing high sensitivity to external stimuli and potential application as a supramolecular biosensor.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Chemistry, Physical
Mhejabeen Sayed, Dilip Kumar Maity, Haridas Pal
Summary: The photophysical properties of two 7-aminocoumarin dyes, C102 and C153, were studied in different aprotic solvents. It was found that the properties of the dyes varied with the polarity of the solvent, with C153 exhibiting unusual behavior in lower polarity solvents. Additionally, the nonradiative decay rates were higher for C102 compared to C153.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Chemistry, Physical
Goutam Chakraborty, Saparya Chattaraj, Haridas Pal
Summary: This study investigates the modulation of photophysical and prototropic properties of the BDZ dye by the sulfobutylether-beta-cyclodextrin (SBE beta CD) host. The SBE beta CD host demonstrates different binding strengths for the protonated and unprotonated forms of the BDZ dye, resulting in a significant upward pKa shift. Furthermore, the dye's structure is constrained upon binding with the host, leading to a substantial enhancement in fluorescence intensity and lifetime, as well as an increase in fluorescence anisotropy decay times, confirming the binding between the dye and host.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Chemistry, Physical
Mhejabeen Sayed, Haridas Pal
Summary: Supramolecular chemistry involving macrocyclic hosts, particularly cyclodextrins, cucurbit[n]urils, and calix[n]arenes, is a highly dynamic and versatile research field with immense potential for applications in nanotechnology, materials science, biosensors, drug delivery, analytical chemistry, and biomedical sciences. These host-guest based supramolecular assemblies can easily respond to external stimuli, leading to the formation of advanced structures such as pseudorotaxanes, rotaxanes, polyrotaxanes, supramolecular polymers, micelles, vesicles, and supramolecular nanostructures, offering future researchers opportunities to develop superior functional materials for diverse applied areas.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Goutam Chakraborty, Alok K. Ray, Prabhat K. Singh, Haridas Pal
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2020)
Article
Chemistry, Physical
Sharmistha Dutta Choudhury, Haridas Pal
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2020)
Article
Chemistry, Physical
Mhejabeen Sayed, Dona M. Tom, Haridas Pal
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2020)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
