4.7 Article

A new strategy for a DNA assay based on a target-triggered isothermal exponential degradation reaction

期刊

CHEMICAL COMMUNICATIONS
卷 47, 期 18, 页码 5262-5264

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc10186b

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资金

  1. National Science Fund for Distinguished Young Scholars [20925520]
  2. Shanghai Science and Technology Committee [09DZ2271800]

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An ultra-sensitive, fast, simple and easily operated method for sequence-specific detection of polynucleotides is proposed herein, which is based on a novel target-triggered isothermal exponential degradation reaction (TT-isoTexpDR) and the color change of probe-functionalized gold nanoparticles.

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