期刊
CHEMICAL COMMUNICATIONS
卷 47, 期 35, 页码 9792-9794出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13615a
关键词
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A water soluble vitamin B-12-rhenium conjugate was synthesized and used in concert with intrinsic factor to screen for cubilin receptor-mediated uptake in lung cancer cells. Internalization of the conjugate demonstrated that it could be used to rapidly screen for the cubilin receptor in living cells, subsequently confirmed with Western blotting and RT-PCR.
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