Article
Materials Science, Multidisciplinary
Mikhail Dobrynin, Elina Sokolova, Mikhail A. Kinzhalov, Andrey S. Smirnov, Galina L. Starova, Vadim Yu Kukushkin, Regina M. Islamova
Summary: In this study, a family of platinum complexes were synthesized and used as hydrosilylation catalysts to prepare luminescent silicone rubbers. The silicone rubbers and the complexes exhibited similar emission spectra in the green region and strong phosphorescence, with potential applications in protective coatings and phosphor-converted white light-emitting diodes.
ACS APPLIED POLYMER MATERIALS
(2021)
Review
Toxicology
Maria Kozurkova
Summary: The potential of acridines as topoisomerase II inhibitors was first discovered in 1984, leading to the testing of numerous derivatives with various substituents. Recent studies have focused on novel acridine derivatives and their activity against topoisomerase II.
JOURNAL OF APPLIED TOXICOLOGY
(2022)
Article
Chemistry, Medicinal
Jing Yang, Lei Chen, Peng-Chao Wang, Bo Yang, Chuan-Zhu Gao
Summary: This study developed a series of cyclometalated platinum (II) complexes with near-infrared phosphorescent emission targeting carbonic anhydrase IX (CAIX). These complexes showed high binding affinity and effective inhibition on CAIX in vitro. The complexes demonstrated significantly enhanced therapeutic effect on multiple cancer cell lines compared to cisplatin and had higher selectivity towards cancer cells.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Sabrina X. Van Ravenstein, Kavi P. Mehta, Tamar Kavlashvili, Jo Ann W. Byl, Runxiang Zhao, Neil Osheroff, David Cortez, James M. Dewar
Summary: Using Xenopus egg extracts, this study demonstrates that the TOP2 poisons etoposide and doxorubicin inhibit DNA replication through different mechanisms. Etoposide induces TOP2-dependent DNA breaks and TOP2-dependent fork stalling, while doxorubicin stalls replication forks independently of TOP2 by intercalating into parental DNA.
Article
Chemistry, Inorganic & Nuclear
Francesco Fagnani, Alessia Colombo, Claudia Dragonetti, Dominique Roberto, Daniele Marinotto
Summary: This study focuses on the substitution of the chlorido ligand in a cyclometalated complex with thioacetate, resulting in a thiolato complex. The photophysical properties of this complex were investigated in different states, revealing changes in phosphorescence spectra, lifetime decays, and quantum yield with increasing complex concentration. The tuning of emission spectra was found to depend on the competition between monomeric and aggregate emissive states.
INORGANICA CHIMICA ACTA
(2022)
Article
Chemistry, Multidisciplinary
Hamid R. Shahsavari, Samira Chamyani, Reza Babadi Aghakhanpour, Vahideh Dolatyari, Sareh Paziresh
Summary: Two categories of cycloplatinated(ii) complexes were synthesized and their photophysical properties were investigated. The absorption and emission spectra of these complexes showed distinct differences under different conditions.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Dominique Roberto, Alessia Colombo, Claudia Dragonetti, Francesco Fagnani, Massimo Cocchi, Daniele Marinotto
Summary: Substitution of the chlorido ligand with 4-phenylthiazole-2-thiolate leads to thiolato complexes with tunable emission color and high luminescence quantum yield.
Article
Chemistry, Inorganic & Nuclear
Hua-Hong Zhang, Qian-Ying Yang, Xiao-Wei Qi, Shi-Shu Sun, Bang-Sen Li, Da-Shuai Zhang, Xiao-Peng Zhang, Zai-Feng Shi
Summary: The mechanochromic and mechanoluminescent properties of a series of fluoro-substituted chiral Pt(NNC)Cl complexes have been investigated, showing blue-shift in absorption and emission with F substitutes. Different mechanochromic and mechanoluminescent behaviors were observed in obtained yellow or orange solid powders of cyclometalated platinum(II) complexes. Notably, (-)-3FC yellow crystallites exhibit a sensitive and contrast mechanochromic and mechanoluminescent phenomenon, with color and luminescence changing significantly. The reversible nature of these behaviors with multiple cycles and the recovery of original crystallites with acetone drop were also demonstrated.
INORGANICA CHIMICA ACTA
(2021)
Article
Chemistry, Applied
Hua-Hong Zhang, Jing Jing, Shui-Xing Wu, You-Ping Luo, Shi-Shu Sun, Da-Shuai Zhang, Zai-Feng Shi, Xiao-Peng Zhang
Summary: This study successfully synthesized two pairs of enantiomeric pinene-containing Pt(II) isocyanide complexes and demonstrated their ability to form chiral ordered self-assemblies in nonpolar solvents. Additionally, these complexes exhibited aggregation-induced emission enhancement behavior in specific solvents and showed tunable emission colors and aggregation states by controlling the solvent and temperature.
Article
Chemistry, Inorganic & Nuclear
Juan-Carlos Lopez-Lopez, Delia Bautista, Pablo Gonzalez-Herrero
Summary: The synthesis and photophysical properties of bis-cyclometalated halido(aryl) Pt(iv) complexes are reported. The introduction of aryl ligands through different methods and the comparison of chlorido and fluorido derivatives in terms of emission lifetimes and radiative rate constants are discussed. The study also highlights the role of radical species in the activation of solvents during the oxidative addition reaction.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Multidisciplinary
Hamid R. Shahsavari, Sareh Paziresh
Summary: The synthesis and characterization of a series of cycloplatinated(II) complexes, as well as their photophysical properties and electronic transitions, were investigated in this study. The phosphine-containing dfppy derivatives exhibit dual emission bands in the solid state and have higher quantum yield values compared to ppy analogs. Complexes with PPh(2)py show stronger emissions than those containing PPh3.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Mina Sadeghian, David Gomez de Segura, Mohsen Golbon Haghighi, Nasser Safari, Elena Lalinde, M. Teresa Moreno
Summary: This study presents the synthesis and characterization of two series of mononuclear and symmetrical binuclear cycloplatinated(II) complexes. The structures of these complexes were determined by single-crystal X-ray diffraction. One of the complexes showed a high quantum yield of up to 21% in the solid state. Density functional theory (DFT) and time-dependent DFT calculations were used to interpret the absorption and emission properties of these complexes.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Andrea Corral-Zorzano, David Gomez de Segura, Elena Lalinde, M. Teresa Moreno
Summary: We have investigated a range of dicationic heteroleptic complexes with two cyclometalating 2-phenylbenzothiazole (pbt) groups and a phenanthroline-based ligand. The photophysical and electrochemical properties of these complexes were studied, and different emissive states were observed depending on the medium and excitation wavelength. Theoretical calculations supported these findings and provided insights into the luminescence of these PtIV complexes.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Sergej Stipurin, Thomas Strassner
Summary: A total of six novel platinum complexes were successfully synthesized from saturated N-heterocyclic carbene precursors, showing strong emissive properties in the sky-blue region of the visible spectrum with quantum yields up to 71% in a PMMA matrix. The structures were characterized by NMR experiments and solid-state analyses, confirming the cyclometalation and saturated backbone of the NHC motif. DFT calculations were used to examine the photophysical and electrochemical properties of the platinum complexes.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Natalia Fernandez-Pampin, Monica Vaquero, Tania Gil, Gustavo Espino, Dario Fernandez, Begona Garcia, Natalia Busto
Summary: This article presents the synthesis of three neutral Pt(II) complexes and their antitumor activities. The complexes showed higher cytotoxicity than cisplatin and exhibited different interactions with DNA and serum proteins. The induction of apoptosis through reactive oxygen species generation may be the main mechanism of action for two of the complexes.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Sharon Lai-Fung Chan, Tsz Lung Lam, Chen Yang, Siu-Cheong Yan, Nga Man Cheng
CHEMICAL COMMUNICATIONS
(2015)
Article
Chemistry, Multidisciplinary
Chi-Tung Yeung, Wesley Ting Kwok Chan, Siu-Cheong Yan, Kwan-Leung Yu, King-Him Yim, Wing-Tak Wong, Ga-Lai Law
CHEMICAL COMMUNICATIONS
(2015)
Article
Chemistry, Multidisciplinary
Hai-Jing Zhong, Lihua Lu, Ka-Ho Leung, Catherine C. L. Wong, Chao Peng, Siu-Cheong Yan, Dik-Lung Ma, Zongwei Cai, Hui-Min David Wang, Chung-Hang Leung
Article
Cell Biology
Guo-Qing Chen, Rui-Hong Gong, Da-Jian Yang, Ge Zhang, Ai-Ping Lu, Siu-Cheong Yan, Shu-Hai Lin, Zhao-Xiang Bian
CELL DEATH & DISEASE
(2017)
Article
Multidisciplinary Sciences
Chi-Tung Yeung, King-Him Yim, Ho-Yin Wong, Robert Pal, Wai-Sum Lo, Siu-Cheong Yan, Melody Yee-Man Wong, Dmitry Yufit, Danil E. Smiles, Laura J. McCormick, Simon J. Teat, David K. Shuh, Wing-Tak Wong, Ga-Lai Law
NATURE COMMUNICATIONS
(2017)
Article
Biochemistry & Molecular Biology
Yi-Yong Yan, Jia-Heng Tan, Yu-Jing Lu, Siu-Cheong Yan, Kwok-Yin Wong, Ding Li, Lian-Quan Gu, Zhi-Shu Huang
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
(2013)
Article
Biochemistry & Molecular Biology
Yong Wang, Fung-Yi Chan, Ning Sun, Hok-Kiu Lui, Pui-Kin So, Siu-Cheong Yan, Kin-Fai Chan, Jiachi Chiou, Sheng Chen, Ruben Abagyan, Yun-Chung Leung, Kwok-Yin Wong
CHEMICAL BIOLOGY & DRUG DESIGN
(2014)
Article
Chemistry, Multidisciplinary
Kwong-Chak Cheung, Wing-Leung Wong, Ming-Him So, Zhong-Yuan Zhou, Siu-Cheong Yan, Kwok-Yin Wong
CHEMICAL COMMUNICATIONS
(2013)
Article
Chemistry, Multidisciplinary
Chi-Tung Yeung, Ho-Lun Yeung, Wesley Ting Kwok Chan, Siu-Cheong Yan, Eric C. Y. Tam, Ka-Leung Wong, Chi-Sing Lee, Wing-Tak Wong
Article
Multidisciplinary Sciences
Ning Sun, Fung-Yi Chan, Yu-Jing Lu, Marco A. C. Neves, Hok-Kiu Lui, Yong Wang, Ka-Yan Chow, Kin-Fai Chan, Siu-Cheong Yan, Yun-Chung Leung, Ruben Abagyan, Tak-Hang Chan, Kwok-Yin Wong
Article
Chemistry, Multidisciplinary
Bipin Kumar, Nuruzzaman Noor, Suman Thakur, Ning Pan, Harishkumar Narayana, Siu-cheong Yan, Faming Wang, Parth Shah
Article
Chemistry, Multidisciplinary
Yong Wang, Zhiguang Liang, Yuanyuan Zheng, Alan Siu-Lun Leung, Siu-Cheong Yan, Pui-Kin So, Yun-Chung Leung, Wing-Leung Wong, Kwok-Yin Wong
Summary: A series of isatin derivatives with different substituent groups were systematically designed and synthesized to study their inhibition of bacterial enzyme activity and antimicrobial potency. Modifying the substituent positions can maximize the antimicrobial potency and inhibitory action against the bacterial enzyme, leading to better understanding of the structure-activity relationship.
Article
Chemistry, Multidisciplinary
Zhiyuan Fang, Yanan Li, Yuanyuan Zheng, Xiaomei Li, Yu-Jing Lu, Siu-Cheong Yan, Wing-Leung Wong, Kin-Fai Chan, Kwok-yin Wong, Ning Sun
Article
Chemistry, Multidisciplinary
Kin-Fai Chan, Ning Sun, Siu-Cheong Yan, Iris L. K. Wong, Hok-Kiu Lui, Kwan-Choi Cheung, Jian Yuan, Fung-Yi Chan, Zhiwei Zheng, Edward W. C. Chan, Sheng Chen, Yun-Chung Leung, Tak Hang Chan, Kwok-Yin Wong
Article
Clinical Neurology
Sharon Lai-Fung Chan, Lihua Lu, Tsz Lung Lam, Siu-Cheong Yan, Chung-Hang Leung, Dik-Lung Ma
CURRENT ALZHEIMER RESEARCH
(2015)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
