Article
Cell & Tissue Engineering
Angela Semitela, Goncalo Ramalho, Ana Capitao, Catia Sousa, Alexandrina F. Mendes, Paula A. A. P. Marques, Antonio Completo
Summary: Electrospinning is widely used in fabricating fibrous scaffolds for cartilage tissue engineering. However, small pores in the scaffold restrict cell infiltration. Bio-electrospraying provides a solution by incorporating chondrocytes into the fibers during electrospinning. Through experiments, it was found that chondrocytes survived and functioned well under certain electrospraying conditions. The combination of electrospraying and polymer electrospinning shows promising results for the delivery and development of cellularized cartilage tissue constructs.
JOURNAL OF TISSUE ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Mahmoud A. El-Jemni, Hamdy H. Hassan, Sayed S. Abd El Rehim, Hesham S. Abdel-Samad
Summary: In this study, a highly efficient Nickel/CX/G electrode for electrocatalysis of ethanol oxidation reaction was prepared by the synergism between nano nickel particles and its carbon xerogel support, CX, together with their graphite substrate, G. The optimum electrode was obtained by doping 6% weight of Ni in CX matrix and drop-casting it on a graphite surface. The catalyst structure and morphology were characterized using XRD, SEM, TEM, and FTIR techniques. The optimized electrode exhibited an oxidation peak current density of 5925 A.g(Ni)(-1) and considerable stability, making it a promising candidate for an anode in the Direct Alkaline Ethanol Fuel Cell, DAEFC.
Article
Engineering, Environmental
Krzysztof Kusmierek, Wojciech Kicinski, Malgorzata Norek, Marek Polanski, Boguslaw Budner
Summary: Heteroatom-doped carbon gels were studied for their efficiency in oxidative and adsorptive degradation/removal of phenolic compounds. It was found that the co-doping of iron and nitrogen in carbon materials enhances catalytic properties and adsorption capacity, leading to more efficient degradation of organic pollutants.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Shuaishuai Xu, Yang Gao, Tao Liang, Lipeng Zhang, Bin Wang
Summary: In this study, an N, O co-doped carbon xerogel-based electrocatalyst (NO-CX) was prepared by a simple and economical method. The NO-CX catalyst exhibited high H2O2 selectivity and production rate within a specific potential range. Density functional theory calculations revealed the coupling effect of N and O on catalytic activity.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Applied
Jia-Peng Dai, Dong Li, Ya-Ling He, Shen Du, Jun-Ning Li
Summary: The atomic model of carbon xerogel microporous structure is reconstructed using a modified virtual porous carbon model, and the physical parameters of the reconstructed model are found to agree well with experimental data, particularly the predicted nitrogen adsorption isotherm. The study further investigates the adsorption and diffusion of gas in the carbon xerogel microporous structure at the pore-scale, finding that the desorption of adsorbates in ultramicropores contributes significantly to the decrease in isosteric adsorption heat and excess adsorption with increasing temperature. The microporous structure also exhibits strong selectivity for oxygen due to molecular sieving effects and solid-fluid interactions with the pore wall. The paper concludes that the desorption of oxygen in ultramicropores and its increasing steric repulsion at higher temperatures leads to a decrease in selectivity and a narrowing gap between isosteric adsorption heat for nitrogen and oxygen. Pore-scale analysis shows a systematic migration of gas molecules from ultramicropores to wider areas, resulting in gas diffusivity showing an approximately linear relationship with temperature.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Biophysics
Xiaqing Zhou, Gan Zhou, Radoslaw Junka, Ningxiao Chang, Aneela Anwar, Haoyu Wang, Xiaojun Yu
Summary: Artificial bone grafts offer advantages in promoting cell proliferation and differentiation in bone tissue regeneration, while using 3D printing technology combined with bio-fabrication methods to prepare porous spiral scaffolds can significantly improve cell growth and differentiation.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Agricultural Engineering
Ajit Kumar, Jothika Jeyabalan, V. Vishnu Priyan, Chandi Charan Patra, Selvaraju Narayanasamy
Summary: A novel adsorbent, CMC-T-CH, was synthesized by crosslinking carboxymethyl cellulose (CMC) and chitosan (CH) with triethylenetetramine. The effectiveness of CMC-T-CH in removing Direct blue (DB) and Congo red (CR) dyes was investigated. Various methods were employed to study the physicochemical characteristics of CMC-T-CH and it was found that the optimized conditions for the removal process were pH 6 for CR and pH 5 for DB at 35°C. Langmuir isotherm and pseudo-second-order kinetic models were used to analyze the interaction between adsorbate and adsorbent. The maximum theoretical adsorption capacities achieved were 519.53 mg/g for CR and 534.25 mg/g for DB. The dye-loaded CMC-T-CH could be regenerated and the phytotoxicity assay demonstrated the potential of CMC-T-CH in the elimination of CR and DB.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Analytical
Weimin Wan, Ziqi Li, Xi Wang, Fei Tian, Jian Yang
Summary: This study presents a green, fast and efficient strategy for constructing a fluorescent nanosystem based on functionalized hydroxyapatite (HAP) and polyethyleneimine (PEI) for cell imaging and drug delivery. The nanosystem showed rapid cellular uptake and high drug loading capacity, and exhibited enhanced drug release under acidic conditions. Furthermore, the functionalized HAP-PEI ink was successfully used for 3D cell culture. These findings highlight the potential of this strategy for bio-imaging, drug delivery and bio-printing.
Review
Engineering, Biomedical
Haoyu Li, Huixing Zhou, Chongwen Xu, Yen Wei, Xiuying Tang
Summary: This review provides an overview of the mechanisms, advantages, and limitations of scaffold-based and scaffold-free strategies in tissue engineering. It compares the strengths and weaknesses of these two strategies and discusses the challenges in their future development. The review concludes that integrating scaffold-based and scaffold-free strategies can overcome the problems in biofabrication.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Biochemistry & Molecular Biology
Mehdi Azizi, Amin Shavandi, Masoud Hamidi, Shayan Gholizadeh, Mahnaz Mohammadpour, Mohammad Saeid Salami, Hadi Samadian
Summary: Tissue engineering is an innovative approach that combines engineering, biomaterials, and biomedicine to improve conventional bone defect treatment. This study developed bioengineered electroactive and bioactive mineralized carbon nanofibers as a scaffold for bone tissue engineering. The fabricated scaffold showed osteoactivity, electrical conductivity, and biocompatibility, making it an effective solution for bone tissue engineering.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Environmental Sciences
Mohammad Ehtisham Khan, Akbar Mohammad, Taeho Yoon
Summary: This review validates the importance of CQDs in multiple research fields, summarizes their extensive photonic and electronic properties, and highlights the significant advantages in visible-light-induced catalytic applications. The article also examines the problems and future directions in this research field and presents the decisive role of CQDs in photocatalysis, bio-imaging, and bio-sensing applications.
Article
Optics
Ziqi Yuan, Ying Liu, Min Xiang, Yang Gao, Yuchen Suo, Mao Ye, Yueyang Zhai
Summary: This study proposes a compact and high-resolution four-channel optically pumped magnetometer for bio-magnetic field measurement. The optics design used improves the uniformity of atomic polarization and achieves high consistency in pursuit of better low-frequency noise suppression. Experimental results show high accuracy and the device is capable of obtaining distinguishable adult magnetocardiography (MCG) and effectively suppressing maternal cardiac signals for fetal MCG (fMCG) measurements. A miniaturized sensor composed of prisms and a polarization-maintaining fiber is proposed, with great potential for future bio-magnetic imaging systems.
OPTICS AND LASER TECHNOLOGY
(2023)
Article
Crystallography
Luis Humberto Campos Becerra, Alejandro Torres Castro
Summary: This research proposes a bio-fabrication method using a selection process of different elements to create a porous scaffold, utilizing magnesium alloyed with calcium and zinc, for potential applications in treating specific pathologies, bone fixation, and oncology. The alloy may also serve as a complementary treatment for osteosarcoma through oxidative degradation-induced basification. Cell viability evaluation and morphological characterization of the alloy will help enhance understanding of its applicability for new surgical techniques and alternative treatments in various medical specialties.
Article
Engineering, Biomedical
Shir Wertheimer, Mirit Sharabi, Ortal Shelah, Ayelet Lesman, Rami Haj-Ali
Summary: Cardiovascular diseases are the leading cause of death globally, with coronary artery disease accounting for 42% and often requiring surgical intervention. A new biocomposite material system using long collagen fibers from soft corals embedded in an alginate matrix was introduced to develop tissue-engineered small-diameter blood vessels. This novel graft demonstrated both mechanical and biological compatibility and shows potential for small-diameter blood vessel replacement.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Wenjun Ma, Sida Ling, Yingzhe Liu, Zhuo Chen, Jianhong Xu
Summary: Ideal joint wound dressings should have mechanical properties including stretchability and adhesion, as well as functions such as sterilization or motion monitoring. Inspired by the spiral arteries in the endometrium, alginate-based helical fibers were introduced into polyacrylamide/gelatin to obtain composite polymer membranes, achieving a combination of mechanical and functional properties.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Amit Kumar, Archana Kumari, Shwetank Asu, Dipranjan Laha, Sumanta Kumar Sahu
Article
Chemistry, Physical
Sourav Bag, Chengtian Zhou, Samuel Reid, Shantel Butler, Venkataraman Thangadurai
JOURNAL OF POWER SOURCES
(2020)
Article
Materials Science, Multidisciplinary
Chengtian Zhou, Sourav Bag, Tianhao He, Bowen Lv, Venkataraman Thangadurai
APPLIED MATERIALS TODAY
(2020)
Article
Chemistry, Multidisciplinary
Ville Hynninen, Sourov Chandra, Susobhan Das, Mohammad Amini, Yunyun Dai, Sakari Lepikko, Pezhman Mohammadi, Sami Hietala, Robin H. A. Ras, Zhipei Sun, Olli Ikkala, Nonappa
Summary: The research demonstrates a method for preparing fibers through wet spinning using nontoxic luminescent nanomaterials and efficient environmentally friendly extrusion methods, resulting in composite fibers with excellent optical and mechanical performance.
Review
Oncology
Stefano Persano, Pradip Das, Teresa Pellegrino
Summary: Immunotherapy is an effective treatment option for various cancers, but faces limitations such as immune evasion and low response rates. The rapid advancement of nanotechnology is leading to the development of novel synthetic nanocarriers for precise delivery of immunotherapeutics. Magnetic nanostructured formulations are particularly promising due to their easy functionalization, low cost, and suitability for magnetically-guided and heat-based therapies. Combinatorial magnetic-based therapies have the potential to overcome challenges in cancer immunotherapy by enhancing drug delivery and effectiveness.
Review
Materials Science, Multidisciplinary
Pradip Das, Nikhil R. Jana
Summary: Biocompatible and biodegradable polyaspartamide-derived formulations have shown great potential in diverse biomedical applications, with successful utilization as coating materials for inorganic nanoparticles, delivery carriers for therapeutic agents, and scaffolds in tissue engineering. Their simple synthesis methods, biodegradability, and successful preclinical validations contribute to their emerging role in the field of nanomedicine.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Sourov Chandra, Alice Sciortino, Shruti Shandilya, Lincan Fang, Xi Chen, Nonappa, Hua Jiang, Leena-Sisko Johansson, Marco Cannas, Janne Ruokolainen, Robin H. A. Ras, Fabrizio Messina, Bo Peng, Olli Ikkala
Summary: This study presents a new strategy for in situ site-selective Ag-doping at the central core of AuNCs using sulphated colloidal surfaces as templates. This approach greatly improves the photoluminescence quantum efficiency of AuNCs by eliminating nonradiative losses.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Usharani Nagarajan, Sourov Chandra, Tomohiko Yamazaki, Naoto Shirahata, Francoise M. Winnik
Summary: Semiconductor nanocrystals or quantum dots (QDs) have gained attention in biomedical research as versatile probes for imaging, sensing, and therapies. The interactions between proteins and QDs are crucial for their use in biological applications and are not fully understood. Asymmetric flow field-flow fractionation (AF4) is a promising method for analyzing these interactions. AF4 coupled with other techniques can determine the binding affinity and stoichiometry of protein-QD interactions. This study used AF4 to investigate the interaction between fetal bovine serum (FBS) and silicon quantum dots (SiQDs), providing crucial information on their size, shape, and interaction with serum components.
Article
Materials Science, Multidisciplinary
Sourov Chandra, Alice Sciortino, Susobhan Das, Faisal Ahmed, Arijit Jana, Jayoti Roy, Diao Li, Ville Liljestrom, Hua Jiang, Leena-Sisko Johansson, Xi Chen, Marco Nonappa, Marco Cannas, Thalappil Pradeep, Bo Peng, Robin H. A. Ras, Zhipei Sun, Olli Ikkala, Fabrizio Messina
Summary: A study reports on an atomically precise ultrasmall Au(I)(6) nanocluster with unique properties, including efficient third harmonic generation, intense photoluminescence, ultrafast quantum coherence, and electron accepting properties. The nanoclusters were formed through a sequential reduction protocol using ascorbic acid, and showed strong third harmonic generation response and excellent stability. The results suggest potential applications in multifunctional devices, fast photoswitches, and quantum colloidal devices.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Pradip Das, Silvia Pujals, Lamiaa M. A. Ali, Magali Gary-Bobo, Lorenzo Albertazzi, Jean-Olivier Durand
Summary: In this study, the degradation of biodegradable periodic mesoporous organosilica nanoparticles (nanoPMOs) triggered by glutathione and the multivalency of antibody-conjugated nanoPMOs were quantified using direct stochastic optical reconstruction microscopy (dSTORM). The impact of these properties on cancer cell targeting, drug loading and release capability, and anticancer activity were also investigated. The higher spatial resolution of dSTORM imaging enabled the characterization of structural properties of fluorescent and biodegradable nanoPMOs. The quantification of nanoPMOs' biodegradation using dSTORM imaging demonstrated their excellent structure-dependent degradation behavior at a higher glutathione concentration. The surface functionality of anti-M6PR antibody-conjugated nanoPMOs, as quantified by dSTORM imaging, played a key role in prostate cancer cell labeling and the higher biodegradability and cancer cell-targeting properties of nanorods conjugated with oriented antibody effectively delivered the anticancer drug doxorubicin to cancer cells, exhibiting potent anticancer effects.
Article
Chemistry, Physical
Pradip Das, Lucia Salvioni, Manuela Malatesta, Federica Vurro, Silvia Mannucci, Marco Gerosa, Maria Antonietta Rizzuto, Chiara Tullio, Anna Degrassi, Miriam Colombo, Anna M. Ferretti, Alessandro Ponti, Laura Calderan, Davide Prosperi
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2020)
Article
Chemistry, Multidisciplinary
Arijit Jana, Papri Chakraborty, Wakeel Ahmed Dar, Sourov Chandra, Esma Khatun, M. P. Kannan, Robin H. A. Ras, Thalappil Pradeep
CHEMICAL COMMUNICATIONS
(2020)
Article
Nanoscience & Nanotechnology
Michele Mauri, Veronica Collico, Lucia Morelli, Pradip Das, Isabel Garcia, Jesus Penaranda Avila, Michela Bellini, Rany Rotem, Marta Truffi, Fabio Corsi, Roberto Simonutti, Luis M. Liz-Marzan, Miriam Colombo, Davide Prosperi
ACS APPLIED NANO MATERIALS
(2020)
Article
Electrochemistry
Chengtian Zhou, Sourav Bag, Bowen Lv, Venkataraman Thangadurai
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2020)
Article
Chemistry, Physical
Sourav Bag, Chengtian Zhou, Patrick J. Kim, Vilas G. Pol, Venkataraman Thangadurai
ENERGY STORAGE MATERIALS
(2020)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
