Review
Chemistry, Multidisciplinary
Evgeny Apartsin, Anne-Marie Caminade
Summary: Amphiphilic dendrons are precisely defined structures composed of hydrophilic functions on the surface and hydrophobic tails linked to the core. They can self-associate at the air-water interface, forming micelles, vesicles, or other structures suitable for encapsulating bioactive substances for delivery to cells.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Materials Science, Biomaterials
Changyu Shao, Zhisen Zhang, Wenjing Jin, Zhan Zhang, Biao Jin, Shuqin Jiang, Haihua Pan, Ruikang Tang, James J. De Yoreo, Xiang Yang Liu
Summary: The self-assembled fibrils of collagenlike peptide (POG10) and oriented mineralization of HAP crystals are used to produce bonelike composite materials, inspired by the molecular structure of collagen-I, which can eliminate the gap spaces in collagen-I fibrils.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2021)
Article
Pharmacology & Pharmacy
Martina Veliskova, Milan Zvarik, Simon Suty, Juraj Jacko, Patrick Mydla, Katarina Cechova, Daniela Dzubinska, Marcela Morvova, Maksim Ionov, Maria Terehova, Jean-Pierre Majoral, Maria Bryszewska, Iveta Waczulikova
Summary: Drug delivery by dendron-based nanoparticles is widely studied for medical purposes. This study investigated the interaction of amphiphilic dendrons with blood samples. The researchers found a concentration-dependent increase in whole blood viscosity, particularly in males, likely caused by the formation of aggregates. The interaction was determined to be electrostatic in nature. Higher dendron concentrations disrupted membrane structures and increased the likelihood of forming larger aggregates, potentially impacting blood flow when used in vivo. Blood viscosity measurements were suggested for early-stage investigations to optimize drug carrier properties.
Article
Biochemistry & Molecular Biology
Jianan Zhang, Xueting Lu, Wen Li, Afang Zhang
Summary: This study reports the supramolecular chiral assembly of amphiphilic dendronized tetraphenylethylenes in aqueous solutions. The supramolecular aggregates exhibited thermoresponsive behavior and aggregation-induced fluorescent emission, which could be reversibly tuned by temperature and pH conditions.
Article
Chemistry, Multidisciplinary
Piotr Szustakiewicz, Natalia Kowalska, Maciej Baginski, Wiktor Lewandowski
Summary: A simple strategy for the fabrication of films of binary nanoparticle assemblies is introduced, with dynamic control over the configuration of gold nanorods and nanospheres achieved through the melting of liquid-crystal-like nanoparticle ligands. This approach provides a route for preparing hierarchical nanoparticle superstructures with applications in reversibly switchable, visible-range plasmonic technologies.
Article
Chemistry, Analytical
Ludovica M. Epasto, Tristan Georges, Albina Selimovic, Jean-Michel Guigner, Thierry Azais, Dennis Kurzbach
Summary: The study reveals that simulated body fluids (SBFs) undergo dynamic nanoscopic conformational rearrangements and form nanoscale inhomogeneities of calcium phosphate (CaP) aggregates. These structures may act as precursors in the crystallization process and are crucial for understanding nonclassical crystallization phenomena.
ANALYTICAL CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Dong Wang, Xing Zhou, Jingrui Deng, Changqing Fang, Zhen Wang, Qiang Wang, Yingwei Huang
Summary: By designing a specific peptide sequence to form a self-assembled peptide (SAP) coating, utilizing its abundant functional groups to bind with calcium ions, the formation of c-axis hydroxyapatite crystals is facilitated.
ADVANCED ENGINEERING MATERIALS
(2021)
Review
Engineering, Biomedical
Jue Wang, Zhihui Liu, Bingyu Ren, Qian Wang, Jia Wu, Nan Yang, Xin Sui, Lingfeng Li, Meihui Li, Xiao Zhang, Xinyue Li, Bowei Wang
Summary: Caries and dental erosion are common oral diseases. Biomimetic mineralisation is an ideal approach for restoring enamel, forming a new mineral layer that is tightly attached to the surface. This review highlights the application of various techniques in biomimetic mineralisation for enamel restoration.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Dominika Wrobel, Antonin Edr, Eliska Zemanova, Tomas Strasak, Alena Semeradtova, Jan Maly
Summary: Two types of dendritic structures (DDN-1 and DDN-2) interacted with model lipid vesicles, and the strength of interaction depended on the surface charge of the vesicles. The interaction was more significant with vesicles of higher negative charge. As the concentration of the dendritic structures increased, the interaction also occurred in the hydrophobic part of the bilayer, leading to the formation of dendritic clusters. Therefore, the dendritic structures can be promising platforms for the decoration of exosomes or other natural lipid vehicles, enabling targeted drug delivery or theranostic applications.
CHEMISTRY AND PHYSICS OF LIPIDS
(2023)
Article
Chemistry, Physical
Takeshi Serizawa, Shoki Tanaka, Toshiki Sawada
Summary: The control of molecular arrangement in synthetic assemblies of biorelated molecules is an attractive research focus, with researchers investigating parameters such as temperature, salt concentration, salt species, and solvent species to influence molecular arrangement. Experimental results showed that factors like temperature, inorganic salt concentration and species, and solvent species strongly affected the molecular arrangement in cellulose-based synthetic assemblies.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Urasawadee Amornkitbamrung, Yongjae In, Jung Heon Lee, Zhen Wang, Sang Ho Oh, Heungsoo Shin, Dae Sung Yoon, Hyunjung Shin
Summary: Mineralized fibrils in bone tissue are formed by the assembly of collagen molecules and hydroxyapatite. The nanoconfined crystallization in collagen fibrils remains poorly understood. The mechanism of intrafibrillar mineralization of collagen-PDA fibrils in m-SBF solution was studied, showing that adjusting the phosphate concentration can accelerate the phase transformation of amorphous calcium phosphate to hydroxyapatite.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Zhengyun Wang, Yule Wu, Kunqi Xu, Lipei Jiang, Jiankang Sun, Guangyi Cai, Guangfang Li, Bao Yu Xia, Hongfang Liu
Summary: The concept of hierarchical oriented MOFs has been proposed and successfully applied to create assemblies with high voltage and electricity output through water-evaporation induced electricity generation. The research may offer valuable theoretical guidance for exploring self-assembly of MOFs superstructures and water-evaporation induced electricity generation.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Engineering, Biomedical
Yajie Tian, Jieling Li, Anhe Wang, Zhixin Shang, Honglei Jian, Qi Li, Shuo Bai, Xuehai Yan
Summary: Amino acid derivatives are used to form long-range ordered supramolecular nanostructures with mechanical, electrical, and optical properties, exhibiting semiconductor characteristics. This study uncovers the potential for amino acid molecules to self-assemble into high-performance bioinspired semiconductors, providing a reference for the customized development of biocompatible and environmentally friendly semiconductor materials through rational molecular design.
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Multidisciplinary
Karen Alt, Francesco Carraro, Edwina Jap, Mercedes Linares-Moreau, Raffaele Ricco, Marcello Righetto, Marco Bogar, Heinz Amenitsch, Rania A. Hashad, Christian Doonan, Christoph E. Hagemeyer, Paolo Falcaro
Summary: Antibody-targeted nanoparticles are crucial for precision medicine. A novel one-step synthesis method for oriented monoclonal antibody-decorated metal-organic framework nanocrystals is presented, enabling enhanced targeting properties and preserved recognition abilities. These biocomposites have potential applications in sensing, diagnostic imaging, and targeted drug delivery.
ADVANCED MATERIALS
(2022)
Article
Polymer Science
Haohui Huo, Zepeng Li, Tianyi Tan, Long Chen, Goran Ungar, Richard Hoogenboom, Qilu Zhang, Feng Liu
Summary: This study demonstrates a general approach to asymmetrically localize tadpole-like silver nanoparticles (NPs) in larger polymeric nanostructures through coassembly, providing a new strategy for NP fabrication and offering opportunities for off-center distribution of NPs in hybrid assemblies.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)