Hydrogen bond induced enantioselectivity in Mn(salen)-catalysed sulfoxidaton reactions

A chiral Mn(salen)complex exhibiting two lactam binding sites at two rigid 1,5,7-trimethyl-3-azabicyclo[3.3.1]nonan-2-one skeletons is capable of enantioselective sulfoxidation due to spatially remote substrate hydrogen bonding.