Article
Polymer Science
Daniel J. Whitaker, Zehuan Huang, Brooke W. Longbottom, Renata L. Sala, Guanglu Wu, Oren A. Scherman
Summary: A new synthetic methodology for alkyl pyridinium-containing acrylamide monomers was introduced, which can form inclusion complexes with CB[8] to facilitate supramolecular crosslinking in hydrogels. The resulting hydrogels exhibit greatly enhanced mechanical properties and fluorescence properties desirable for sensing applications by selecting fluorescent pyridine moieties.
Article
Electrochemistry
Dongpeng Mao, Penghu Duan, Xinyao Wang, Peng Wang, Chuanyu Qin, Yunxian Piao
Summary: In this study, a cascade electrochemical reaction-based BaP detection method was proposed using novel synthesized reduced and hierarchically porous biochar (RP-BC) as the conductive and analyte binding material. The RP-BC film coated on a glassy carbon electrode selectively adsorbs and enriches BaP through strong pi-pi electron donor-acceptor (EDA) interaction and pore interception effect, enabling fast (5 min) and selective detection. The method shows a low detection limit of 0.090 nmol.mL(-1) and a linear range of 0.32 to 80 nmol.mL(-1). BaP detection in groundwater and tap water was successfully achieved, suggesting its potential for practical environmental monitoring.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Organic
Jonathan A. Andrews, Loic R. E. Pantaine, Christopher F. Palmer, Darren L. Poole, Michael C. Willis
Summary: A catalyst-free procedure is used to generate primary, secondary, and benzylic alkyl radicals from readily available amines, which are then trapped by SO2 to form sulfonyl radicals. These sulfonyl radicals are then converted into alkyl sulfinate products through hydrogen atom transfer from Hantzsch ester, allowing for the preparation of medicinal chemistry relevant sulfonyl-containing motifs.
Article
Engineering, Chemical
Shi Yuan, Yang Li, Yun Xia, Cordelia Selomulya, Xiwang Zhang
Summary: The study focuses on incorporating potassium cations into reduced graphene oxide (rGO) membranes to form stable and selective K-controlled rGO (K-rGO) membranes for water and NaCl separation. These membranes exhibit enhanced NaCl rejection (91%) due to a strong potassium-ion-pi interaction, providing new insights into the design of selective 2D membranes for desalination, ionic sieving, and other environmental applications.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Chemistry, Inorganic & Nuclear
Carolina Olea Ulloa, Raul Guajardo-Maturana, Alvaro Munoz-Castro
Summary: Recently, it has been discovered that infinitene, which consists of two fused [6]helicene structures with a central crossover section, can form cation-pi bonding with silver ions, leading to changes in its optical rotation properties. This suggests the potential for helicene compounds to form metal complexes.
Article
Chemistry, Physical
Yu Feng, Xindi Huang, Honghong Xu, Jianyong Liu, Peng Xie, Haixiang He, Shibin Yin
Summary: In this study, the sensing mechanism of a novel sensor 1 for the detection of picric acid was explored. The results showed that the optimal interaction between sensor 1 and picric acid was the synergistic effect of intermolecular hydrogen bonding and pi-pi stacking. The strong luminescent properties of sensor 1 depended on intramolecular charge transfer, but the fluorescence of the sensor was quenched upon exposure to picric acid through a photo-induced electron transfer process.
Article
Chemistry, Physical
Yan Wang, Bin Peng, Yuanyuan Gong, Yingrong Xie, Tingting Feng, Xiaolin Liu, Bowei Chen, Yong Zhang
Summary: Efficient extraction of uranium is important for environmental remediation and addressing the shortage of uranium storage. A new type of porous indole-based polymer (PHTPIAAs) with amino acid and carboxyl groups was fabricated, which showed promising elimination properties for uranium in aqueous solution. The PHTPIAA-2 exhibited a fast uptake rate (50.0 min) and high removal efficiency (97.2%), with a maximum uptake capacity of 457 mg g(-1) at 298 K. The regenerated PHTPIAA-2 maintained an 80.2% removal efficiency after 5 cycles using hydrochloric acid (HCl, 0.1 mol L-1) as eluant. These findings demonstrate the valuable potential of this indole-based polymer in extracting and recovering uranium from various uranium-containing aqueous solutions.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Medicinal
Qijie Gong, Quanwei Yu, Nan Wang, Jiabao Hu, Pengfei Wang, Fulai Yang, Tian Li, Qidong You, Xiang Li, Xiaojin Zhang
Summary: In this study, a series of novel NQO1 substrates were designed by introducing aliphatic nitrogen-containing side chains to form cation-pi interactions with the L-shaped pocket of NQO1. Compound 4 was identified as the most efficient substrate for NQO1, with high reduction rate and catalytic efficiency, as well as increased water solubility. Compound 4 showed potent antitumor activity against NQO1-rich cancer cells through ROS generation, highlighting the potential of cation-pi interactions for developing promising NQO1-targeting antitumor candidates with improved druglike properties.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Tamilselvi Gurusamy, Rajendran Rajaram, Raja Murugan, Kothandaraman Ramanujam
Summary: This study successfully developed a novel electrode matrix for the electrochemical determination of hydrogen peroxide, using a combination of multiwalled carbon nanotubes and polymer modification. The electrode demonstrated a low detection limit and high sensitivity in experiments, proving its effectiveness for hydrogen peroxide sensing.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Analytical
Wei Feng, Xiao-Jun Liu, Min-Jie Xue, Qin-Hua Song
Summary: In this study, a fluorescent probe with two sensing sites was developed to detect and distinguish mustard gas and phosgene. The probe showed high sensitivity and selectivity towards mustard gas, as well as high selectivity towards phosgene. Additionally, a portable test strip was prepared to qualitatively and quantitatively detect 2-chloroethyl ethyl sulfide and phosgene using the RGB channel intensity of the test strip measured by a smartphone with an RGB color application.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Bi Xiong, Shanshan Mao, Fan Ding, Tao Shen, Jiaojiao Wang, Xin Jin, Manglai Gao
Summary: This study compared the adsorption behavior of two organo-vermiculites functionalized by gemini surfactants on 2-naphthol and naproxen. The results showed that one type of functionalized vermiculite was more effective in removing the pollutants. By studying various influencing factors and adsorption mechanisms, important conclusions were drawn from the research.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Engineering, Environmental
Bin Li, Zhonggang Wang
Summary: There is an urgent demand for sensing materials and portable devices with high sensitivity and specific recognition to monitor pesticide residue. Two fluorescent porous polymers with carbazole-based chromophores decorated by n-butyls were synthesized. The polymers exhibited ultra-sensitive recognizable ability for trifluralin in water and remained consistent quenching efficiencies in various solutions. The portable polymer plates showed visual fluorescent quenching for trifluralin solution at an extremely low concentration, and they could be easily recovered and repeatedly used.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Onur Turhan, Muejgan Yaman, Gokhan Dikmen, Yahya Nural, Ayla Eker Sariboyaci, Burcuguel Altug Tasa, Merve Nur Soykan, Zeynel Seferoglu
Summary: Novel coumarin-hydrazide-hydrazone hybrids were synthesized and investigated for their chemosensor properties. The sensors showed recognition properties of CN-, Co2+, and Ni2+ ions, with visible color changes and significant fluorescent enhancement response.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
Oguzhan Dalkilic, Ebru Bozkurt, Haydar Kilic
Summary: Novel hexaphenylbenzene derivatives were synthesized and their optical properties were investigated. The results showed that HPB-1 and HPB-2 can selectively sense F- ions and be used as turn-on fluorometric sensors.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Spectroscopy
Kumaresan Murugesan, Vanthana Jeyasingh, Sudha Lakshminarayanan, Narayanan Selvapalam, Geetha Dass, Lakshminarayanan Piramuthu
Summary: A new hydrazine-based sensor L has been designed and synthesized, which can detect cyanide through ABIFE and fluoride through ABRFE. The sensor L shows almost the same sensing performance for other tested anions as well.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Review
Chemistry, Inorganic & Nuclear
Min Ge, Shouxin Liu, Jian Li, Meng Li, Shujun Li, Tony D. James, Zhijun Chen
Summary: Luminescent materials have great potential in various fields, and the conversion of biomass resources into functional luminescent materials has gained significant attention. However, only a few reviews have focused on this area. This review aims to address this gap and introduce the types of biomass sources available for the preparation of luminescent materials. It will cover the structure-optical performance correlation, preparation and optical properties, potential applications, and future challenges and perspectives of biomass-derived luminescent materials.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Chemistry, Analytical
Simon M. Wikeley, Pablo Lozano-Sanchez, Marco Caffio, Tony D. James, Frank Marken
Summary: This paper presents the use of boronic acid-based synthetic organic receptor molecules attached to graphene in a new electrochemical sensor concept. The sensor utilizes surface redox polymer indicator displacement and graphene foam electrodes. The sensor shows a concentration-dependent Faradaic current response to lactic acid and can be optimized using impedance spectroscopy based on interfacial electron transfer resistance. Surface-active components from human serum are found to modify the sensor response without affecting its performance.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Multidisciplinary
Hemmat A. Elbadawy, Ali El-Dissouky, Seham M. Hussein, Sara R. El-Kewaey, Souad A. Elfeky, Gamal El-Ghannam
Summary: In this study, a CM-beta CD:nChi:Glu terpolymer was prepared as a nano-adsorbent for the removal of acid red 37 dye. The preparation and characterization of the terpolymer nanocomposite were investigated. The results showed that the terpolymer had a high removal efficiency for the dye under specific conditions, making it a promising adsorbent for the removal of acid red 37 from contaminated water.
FRONTIERS IN CHEMISTRY
(2023)
Article
Nanoscience & Nanotechnology
Tianhong Wu, Shiqing Huang, Xing Feng, Xiaogang Liu, Tony D. James, Xiaolong Sun, Xuhong Qian
Summary: In this research, a photoluminescent platform using amine-coupled fluorophores was developed. The fluorescence turn-on mechanism was proposed to be charge separated induced energy radiative transition for the amine-coupled fluorophore. By utilizing the conjugate acceptor, a new fluorogenic approach was established, allowing for selective detection of cysteine under neutral aqueous conditions. This research also successfully constructed a drug delivery system with controlled release of sulfhydryl drug.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Engineering, Environmental
Wei-Na Wu, Yu-Fei Song, Xiao-Lei Zhao, Yuan Wang, Yun-Chang Fan, Zhi-Hong Xu, Tony D. James
Summary: In this study, a ratiometric mitochondria-targeting fluorescent probe 1 was developed that could respond to bisulphite, pH, and viscosity. Probe 1 exhibited significant signal changes, high sensitivity, outstanding selectivity, and good stability for detecting pH, viscosity, and SO2 in solution. It was also used for imaging pH, viscosity, and SO2 derivatives in live cells and zebrafish, suggesting its potential for identifying mitochondrial dysfunctions.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Si-Lin Xu, Fang-Fang Guo, Zhi-Hong Xu, Yuan Wang, Tony D. James
Summary: A water-soluble fluorescent probe 1 based on chromene-hemicyanine has been developed, which exhibits colorimetric fluorescent response towards hypochlorite (ClO-) with a low LOD (0.082 mu M), and turn-on response to viscosity changes. Due to its low cytotoxicity and good biocompatibility, probe 1 is used to monitor hypochlorous acid and viscosity in mitochondria of living cells and zebrafish.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Multidisciplinary Sciences
Yingxiang Zhai, Shujun Li, Jian Li, Shouxin Liu, Tony D. James, Jonathan L. Sessler, Zhijun Chen
Summary: By treating natural wood with magnesium chloride, it can be converted into a viable room temperature phosphorescence (RTP) material called C-wood. C-wood exhibits intense RTP emission and can be used to create afterglow wood sculptures and printable afterglow fibers for luminescent plastics via 3D printing.
NATURE COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Meng Li, Quanyu Shi, Ningxin Song, Zhijun Chen, Lidong Wang, Tony D. James
Summary: A supramolecular artificial light-harvesting system is constructed in an aqueous environment using carbon dots and TMPyP via electrostatic interactions. The energy transfer from the CDs to the TMPyP occurs upon UV excitation. The CDs-TMPyP system is used as a sensor for Hg(II) in an aqueous solution, and a functional material for the detection and removal of Hg(II) is fabricated by integrating the CDs-TMPyP into a polymer network.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Chemistry, Analytical
Peng Zhang, Xuechuan Wang, Xiao Wang, Chusen Huang, Tony D. James, Xiaolong Sun, Xuhong Qian
Summary: This research developed small molecule-based fluorescent probes for chemoselective labeling of vicinal dithiol-containing proteins (VDPs) in live cells, allowing the study of intracellular redox homeostasis. The probes achieved selective labeling of VDPs through thiol-thiol substitutions on bisvinylogous thioester conjugated acceptors (IDAs). The probes demonstrated high sensitivity, low limit of detection, and selectivity for labeling vicinal dithiols on reduced bovine serum albumin, as well as successfully labeling endogenous VDPs at different redox states in live cells.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Yujie Geng, Hanchen Zhang, Guoyang Zhang, Jiaying Zhou, Mingguang Zhu, Lijun Ma, Xuefei Wang, Tony D. D. James, Zhuo Wang
Summary: Schizophrenia is a common mental disorder with unclear mechanisms. This research developed a near-infrared fluorescent probe for noninvasive detection of endogenous superoxide anion (O-2 (-)) in the brain, providing direct evidence for the relationship between oxidative stress, neuroinflammation, and schizophrenia. Furthermore, the study confirmed the burst of O-2(-) in the brains of first-episode schizophrenic mice and assessed the effect of two atypical antipsychotic drugs on redox homeostasis.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Meng Li, Quanyu Shi, Ningxin Song, Yumeng Xiao, Lidong Wang, Zhijun Chen, Tony D. James
Summary: The shortage of freshwater resources caused by heavy metal pollution is a global issue that greatly impacts environmental protection and human health. Developing innovative and cost-effective materials for detecting and removing heavy metal ions is crucial.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Pei-Hong Tong, Jing-Jing Wang, Xi-Le Hu, Tony D. James, Xiao-Peng He
Summary: Inspired by natural enzymes, a bifunctional metal-organic framework (MOF), AuNPs@PCN-224(Fe), was developed for biosensing applications. The hybridized nanozyme, consisting of ultrasmall gold nanoparticles (AuNPs) and iron porphyrin-based MOF (PCN-224(Fe)), exhibited the catalytic activities of glucose oxidase (GOx) and horseradish peroxidase (HRP). The bifunctional nanozyme enabled a cascade reaction to generate hydrogen peroxide and activate a colorimetric or chemiluminescent substrate. Selectivity over other saccharides and high catalytic activity retention were observed.
Article
Chemistry, Organic
Yiming Zhao, Fernanda Meloni, Louise Male, Cecile S. Le Duff, William D. G. Brittain, Benjamin R. Buckley, John S. Fossey
Summary: The synthesis of atropisomeric phoshino-triazoles is described. Phosphine introduction at the 5-position of a 1,2,3-triazole ring restricts rotation around a triazole-aryl bond. VT NMR and chiral HPLC studies confirm the conformational stability at high temperatures. Gold(i) chloride complexes of single-enantiomer phosphines also show conformational stability.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao, Tony D. James
Summary: Drug-induced liver injury (DILI) is a common cause of acute liver failure in the USA and Europe, but most cases can be recovered or prevented by discontinuing the offending drug. Recent research has found that peroxynitrite (ONOO-) can be used as a potential indicator for early diagnosis of DILI, and there is an urgent need to establish a method to detect and track peroxynitrite in DILI cases. In this study, a FRET-based nano fluorescent probe CD-N-I was developed, which showed high selectivity and sensitivity in detecting peroxynitrite. The probe successfully detected exogenous peroxynitrite in live cells and endogenous peroxynitrite in APAP-induced liver injury of HepG2 cells.
Article
Chemistry, Multidisciplinary
Kai-Cheng Yan, Jordan E. E. Gardiner, Adam C. C. Sedgwick, Naing Thet, Rachel A. A. Heylen, Tony D. D. James, A. Toby A. Jenkins, Xiao-Peng He
Summary: A new fluorescent probe was developed to determine the NTR activity of different bacterial species under various growth conditions, which can be applied in complex clinical environments with high sensitivity and detection accuracy for both planktonic cultures and biofilms.
CHEMICAL COMMUNICATIONS
(2023)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
