4.7 Article

Inhibition of polymerase activity by pristine fullerene nanoparticles can be mitigated by abundant proteins

期刊

CHEMICAL COMMUNICATIONS
卷 46, 期 9, 页码 1404-1406

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/b922711c

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资金

  1. National Natural Science Foundation of China [20707034, 20877091, 20890112]
  2. National Basic Research Program of China [09CB421605, 2010CB933500]
  3. National High Technology Research and Development Program of China [2007AA06A407]

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Pristine fullerene nanoparticles are capable of adsorbing polymerase and significantly inhibiting its biologically important replication activity; however, the inhibition can be partially mitigated by abundant proteins through competitive binding.

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