NIR-enhanced drug release from porous Au/SiO2 nanoparticles

The ability of core/shell SiO2/Au nanoparticles (NPs) to heat upon being exposed to near-infrared (NIR) radiation is well known. In this work we have modified the synthesis procedure to obtain a mesoporous SiO2 core and a porous Au shell that allows drugs to be loaded within the core porous space. The release of a model drug (ibuprofen) upon NIR activation is demonstrated.