Desymmetrizing asymmetric ring expansion: stereoselective synthesis of 7-membered cyclic beta-keto carbonyl compounds with an alpha-hydrogen

Ring expansion of symmetrically substituted cyclohexanones with N-alpha-diazoacetyl camphorsultam was devised as a stereo-selective pathway to the functionalized 7-membered cyclic beta-keto carbonyls having a kinetically stabilized alpha-hydrogen.