4.7 Article

Synthesis of substituted pyridines and pyridazines via ring closing metathesis

期刊

CHEMICAL COMMUNICATIONS
卷 -, 期 21, 页码 3008-3010

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/b904363b

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资金

  1. EPSRC
  2. GlaxoSmithKline
  3. Clarendon Fund (University of Oxford)
  4. EPSRC [EP/F029772/1] Funding Source: UKRI
  5. Engineering and Physical Sciences Research Council [EP/F029772/1] Funding Source: researchfish

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RCM can be used to make aromatic heterocycles, namely pyridines and, for the first time, pyridazines; the key step after RCM involves elimination of sulfinate to provide the aromatic system.

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