Article
Energy & Fuels
Shuang Wu, Hao Peng, Junxuan Ao, Leidong Xie
Summary: This study critically evaluated and predicted the condensed phases in a multicomponent chloride system, and proposed two innovative quaternary eutectic chlorides with low melting points. The experimental results were consistent with the theoretical predictions, indicating the potential of these new chlorides as candidates for thermal energy storage and transfer materials in solar power plants.
SOLAR ENERGY MATERIALS AND SOLAR CELLS
(2022)
Article
Chemistry, Organic
Fei Wang, Yoshihiro Nishimoto, Makoto Yasuda
Summary: This article describes a reaction method catalyzed by indium trihalide, which can insert diazo esters into carbon-halogen bonds, forming new carbon-halogen bonds and elongating the carbon chain.
Article
Electrochemistry
Gulmira Rakhymbay, Khaisa Avchukir, Yedil Konysbay, Florence Vacandio, Raigul Jumanova, Yeldana Bakhytzhan, Ainaz Abildina, Akmaral Argimbayeva
Summary: TiO2 was prepared via a solid-state chemical reaction and used as an anode for magnesium/lithium hybrid-ion batteries. The addition of Cl- anion activated the battery, resulting in the lowest charge transfer resistance and highest capacity. However, TiO2 as an anode material exhibited sluggish electrochemical kinetics in Mg2+/Li+-ion mixed solutions.
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
(2023)
Article
Chemistry, Physical
Shi-Hua Sang, Yun-Yun Gao, Xiao-Feng He, Han-Zhong Zhang, Xue-Qi Wei
Summary: Studying the solubilities of chloride minerals in aqueous solutions is crucial for the separation and enrichment of elements in hydrometallurgy. Investigations of the phase equilibria of the quaternary system KCl-MgCl2-ZnCl2-H2O at 323 K revealed the formation of various double salts. The resulting dry salt phase diagram divided into six crystallization regions, providing insights into the equilibrium solid phases as well as the comparison of ternary subsystems at different temperatures.
JOURNAL OF SOLUTION CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
E. A. Tishchenko, L. V. Myznikov
Summary: Carbamoyl azides can be formed by the reaction of isocyanates with NaN3 in the presence of ZnCl2 in organic solvents. The formation of carbamoyl azides is completed within 5-10 minutes at room temperature, preventing the release of hydrogen azide. The obtained carbamoyl azides can be used for the synthesis of 1-substituted tetrazol-5-ones without isolation.
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Sumathi Suresh, Santanu Bera, Chandramohan Palogi, B. Sundaravel, P. Jegadeesan, T. V. Krishna Mohan
Summary: The magnetite films on carbon steel can be modified in-situ with the introduction of Zn and Mg by hydrothermal process. The film developed in the presence of Zn showed a smaller particle size of 150 nm after 240 hours exposure compared to that developed in the presence of Mg with a particle size of 223 nm. The depth distribution of Zn and Mg showed that Mg was mainly present on the top surface, while Zn was distributed uniformly across the film depth. Contact angle measurements and electrochemical studies demonstrated that Zn and Mg improved the corrosion resistance of the coated specimens when compared to the passive magnetite layer formed without their presence. The results suggest that Zn is a better candidate for corrosion resistance of carbon steel in high temperature aqueous medium.
CORROSION ENGINEERING SCIENCE AND TECHNOLOGY
(2023)
Review
Chemistry, Organic
Baosheng Wei, Paul Knochel
Summary: Cross-couplings involving organozinc reagents can proceed well in the absence of transition-metal catalysts with reactive electrophiles. Highly diastereoselective and enantioselective cross-couplings can be readily performed with room-temperature configurationally stable alkylzinc species, producing diastereoselectively and enantiomerically enriched products. Highly regioselective magnesiations of functionalized arenes and heteroarenes undergo Negishi or Cu-catalyzed cross-couplings.
SYNTHESIS-STUTTGART
(2022)
Article
Chemistry, Multidisciplinary
Alisa S. Sunagatullina, Ferdinand H. Lutter, Paul Knochel
Summary: In this study, various dialkylmagnesiums were synthesized by reacting primary or secondary alkyl iodides with sBu(2)Mg, and these reagents underwent diverse reactions with different compounds to yield stereodefined products. Mechanistic studies revealed that these reactions proceed via a radical pathway.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Alexander Kremsmair, Andreas Hess, Benjamin Heinz, Paul Knochel
Summary: Mixed TMP-bases are excellent reagents for the metalation of functionalized aromatics and heterocycles. By combining with Lewis acids, the metalation scope can be increased, and regioselectivity switches can be achieved. Highly reactive lithium bases are also compatible with various Lewis acids, and performing metalations in continuous flow using commercial setups allows for practical and convenient reaction conditions.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
A. Hess, H. C. Guelen, N. Alandini, A. Mourati, Y. C. Guersoy, P. Knochel
Summary: This study presents a novel method for the selective ortho, ortho'-functionalization of readily available aryl oxazolines using sBu(2)Mg in toluene followed by trapping reactions with electrophiles. The conversions of these nitriles to valuable heterocycles are reported, and a tentative mechanism is proposed for the reactions.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Organic
Benjamin Heinz, Dimitrije Djukanovic, Fiona Siemens, Mohamed Idriess, Benjamin Martin, Paul Knochel
Summary: The treatment of 3-halopyridines with certain R-substituents in specific positions using specific reagents under specific conditions provided regioselectively synthesized a series of aminated pyridine compounds with high yields. These substitution reactions may proceed via pyridyne intermediates.
SYNTHESIS-STUTTGART
(2022)
Article
Chemistry, Multidisciplinary
Dimitrije Djukanovic, Maximilian A. Ganiek, Kohei Nishi, Konstantin Karaghiosoff, Kazushi Mashima, Paul Knochel
Summary: A new convenient method for the preparation of dicarbamoylzincs is reported in this study. The target compounds were obtained by reacting ZnCl2 and formamides or TMP2Zn with formamides. This method is compatible with sensitive functional groups such as esters, ketones, or nitro groups. The reaction of these dicarbamoylzincs with various functionalized allylic, benzylic, aryl, alkenyl compounds, acid chlorides, aldehydes, or enones resulted in the synthesis of polyfunctional amides in high yields. The C-13 NMR characterization of these new compounds is presented.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Johannes H. Harenberg, Rajasekar Reddy Annapureddy, Konstantin Karaghiosoff, Paul Knochel
Summary: This study reports a lateral sodiation reaction for alkyl(hetero)arenes using a hexane-soluble sodium compound generated on demand, in the presence of TMEDA. The reaction can be conducted under batch and continuous flow conditions. The resulting benzylic sodium species can react with various electrophiles. This method has great potential for synthetic applications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Saroj Kumar Rout, Agonist Kastrati, Harish Jangra, Kuno Schwaerzer, Alisa S. Sunagatullina, Maximilien Garny, Fabio Lima, Cara E. Brocklehurst, Konstantin Karaghiosoff, Hendrik Zipse, Paul Knochel
Summary: DFT calculations can predict the reactivity of uncommon N-heterocyclic scaffolds and facilitate their functionalization. Experimental results show that specific catalysts and reagents can achieve the regioselective derivatization of these compounds.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Alexander Kremsmair, Alisa S. Sunagatullina, Leonie J. Bole, Pasquale Mastropierro, Simon Grassl, Henrik R. Wilke, Edouard Godineau, Eva Hevia, Paul Knochel
Summary: A new method for selectively zincating challenging N-heterocyclic substrates has been reported using mixed Li/Zn bases. The method allows for mild regioselective reactions and provides insights into the composition and reactivity of the reaction mixtures.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Applied
Alisa S. Sunagatullina, Ferdinand H. Lutter, Konstantin Karaghiosoff, Paul Knochel
Summary: We have developed a new iron-catalyzed reaction for converting alkyl iodides into alkylzinc iodides. The reaction exhibits diastereoselective ring closures when a remote double bond is present at position 5. Furthermore, the resulting zinc reagents can be further reacted with various electrophiles under copper or palladium catalysis to provide diverse polyfunctional products.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Chemistry, Multidisciplinary
Alexander Kremsmair, Henrik R. R. Wilke, Johannes H. H. Harenberg, Benjamin R. G. Bissinger, Matthias M. M. Simon, Nurtalya Alandini, Paul Knochel
Summary: This study reports a practical in situ quench procedure for the generation of chiral secondary alkyl lithiums from secondary alkyl iodides. The reaction can be carried out in the presence of various electrophiles, resulting in the preparation of a wide range of optically enriched organic compounds.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Alisa S. Sunagatullina, Andreas Hess, Alexander Kremsmair, Yifan Li, Yi-Hung Chen, Paul Knochel
Summary: We present a novel electrophilic amination method for primary, secondary, and tertiary alkyl, benzylic, and allylic zinc and magnesium organometallics using O-2,4,6-trimethylbenzoyl hydroxylamines (O-TBHAs) with yields ranging from 52-99%. These O-TBHAs exhibit excellent long-term stability and can be conveniently synthesized from various highly functionalized secondary amines through a three-step procedure. The amination reactions demonstrate remarkable chemoselectivity without the need for transition-metal catalysts, and are typically completed within 1-3 hours at 25 degrees Celsius. Furthermore, this electrophilic amination process enables the synthesis of enantioenriched tertiary amines (up to 88% ee) using optically enriched secondary alkylmagnesium reagents of the type s-AlkylMgCH(2)SiMe(3).
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Clemence Hamze, Julie Brossier, Konstantin Karaghiosoff, Edouard Godineau, Paul Knochel
Summary: A regioselective tri- and tetra-functionalization of the pyridazine scaffold was achieved using two readily available building blocks, resulting in the synthesis of a range of pyridazine derivatives.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Agonist Kastrati, Alexander Kremsmair, Alisa S. Sunagatullina, Vasilii Korotenko, Yusuf C. Guersoy, Saroj K. Rout, Fabio Lima, Cara E. Brocklehurst, Konstantin Karaghiosoff, Hendrik Zipse, Paul Knochel
Summary: Straightforward calculations have led to the development of a set of organometallic reactions for the regioselective functionalization of the underexplored fused N-heterocycle imidazo[1,2-a]pyrazine. These reactions provide a way to access polyfunctionalized imidazopyrazine heterocycles.
Article
Chemistry, Multidisciplinary
Andreas Hess, Nurtalya Alandini, Hasret C. Guelen, Jan P. Prohaska, Paul Knochel
Summary: We report the preparation of a new hydrocarbon-soluble magnesium amide TMP2Mg (TMP = 2,2,6,6-tetramethylpiperidyl). This base showed excellent properties for the regioselective magnesiation of various arenes and heteroarenes bearing ethyl esters and carbamates under very mild reaction conditions. Subsequent trapping with aryl iodides (Negishi cross-coupling) gave access to a range of highly functionalized valuable building blocks.
CHEMICAL COMMUNICATIONS
(2022)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
