期刊
CHEMICAL COMMUNICATIONS
卷 -, 期 47, 页码 6387-6389出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b815903c
关键词
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资金
- DFG
- SFB 749
3,6-Dichloropyridazine undergoes a smooth metallation using (tmp)(2)Zn center dot 2MgCl(2)center dot 2LiCl. The resulting bis-organozinc species react with various electrophiles; subsequent functionalization via a second metallation proceeds readily; further reactions with hydrazine lead to highly substituted pyrazolo[3,4-c] pyridazines derivatives.
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