Development of Antivirulence Compounds: A Biochemical Review

Cytosporone B, an Inhibitor of the Type III Secretion System of Salmonella enterica Serovar Typhimurium

(2013) Jianfang Li et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Type III Secretion System Inhibitor Targets YopD while Revealing Differential Regulation of Secretion in Calcium-Blind Mutants of Yersinia pestis

(2013) Danielle L. Jessen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System

(2013) Miles C. Duncan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis of Fluorescent Ring-Fused 2-Pyridone Peptidomimetics

(2013) K. Syam Krishnan et al.   JOURNAL OF ORGANIC CHEMISTRY

Isolation of Salmonella Mutants Resistant to the Inhibitory Effect of Salicylidene acylhydrazides on Flagella-Mediated Motility

(2013) Isabel Martinez-Argudo et al.   PLoS One

The Resveratrol Tetramer (-)-Hopeaphenol Inhibits Type III Secretion in the Gram-Negative Pathogens Yersinia pseudotuberculosis and Pseudomonas aeruginosa

(2013) Caroline E. Zetterström et al.   PLoS One

Identification of the Binding Site of Brucella VirB8 Interaction Inhibitors

(2012) Mark A. Smith et al.   CHEMISTRY & BIOLOGY

FolX fromPseudomonas aeruginosais octameric in both crystal and solution

(2012) Mads Gabrielsen et al.   FEBS LETTERS

Structural Characterisation of Tpx from Yersinia pseudotuberculosis Reveals Insights into the Binding of Salicylidene Acylhydrazide Compounds

(2012) Mads Gabrielsen et al.   PLoS One

Antidotes to anthrax lethal factor intoxication. Part 2: Structural modifications leading to improved in vivo efficacy

(2011) Seongjin Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds

(2011) Dai Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Total synthesis of caminoside B, a novel antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia

(2010) Zaihong Zhang et al.   CARBOHYDRATE RESEARCH

A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium

(2010) Kyota Kimura et al.   JOURNAL OF ANTIBIOTICS

Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity

(2010) Erik Chorell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Salicylidene acylhydrazide-mediated inhibition of type III secretion system-1 in Salmonella enterica serovar Typhimurium is associated with iron restriction and can be reversed by free iron

(2009) Abigail N. Layton et al.   FEMS MICROBIOLOGY LETTERS

Characterization of the Effects of Salicylidene Acylhydrazide Compounds on Type III Secretion in Escherichia coli O157:H7

(2009) J. J. Tree et al.   INFECTION AND IMMUNITY

Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509

(2009) Masato Iwatsuki et al.   JOURNAL OF ANTIBIOTICS

Identification of Novel Non-Hydroxamate Anthrax Toxin Lethal Factor Inhibitors by Topomeric Searching, Docking and Scoring, and in Vitro Screening

(2009) Ting-Lan Chiu et al.   Journal of Chemical Information and Modeling

The QseC Adrenergic Signaling Cascade in Enterohemorrhagic E. coli (EHEC)

(2009) David T. Hughes et al.   PLoS Pathogens

Targeting Type III Secretion in Yersinia pestis

(2008) N. J. Pan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An Inhibitor of Gram-Negative Bacterial Virulence Protein Secretion

(2008) Heather B. Felise et al.   Cell Host & Microbe

Acquired vancomycin resistance in clinically relevant pathogens

(2008) Guido Werner et al.   Future Microbiology

Small-Molecule Type III Secretion System Inhibitors Block Assembly of the Shigella Type III Secreton

(2008) A. K. J. Veenendaal et al.   JOURNAL OF BACTERIOLOGY

Substituted 2-Imino-5-arylidenethiazolidin-4-one Inhibitors of Bacterial Type III Secretion

(2008) Toni Kline et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inter-kingdom signalling: communication between bacteria and their hosts

(2008) David T. Hughes et al.   NATURE REVIEWS MICROBIOLOGY

Targeting QseC Signaling and Virulence for Antibiotic Development

(2008) D. A. Rasko et al.   SCIENCE

The role of the QseC quorum-sensing sensor kinase in colonization and norepinephrine-enhanced motility of Salmonella enterica serovar Typhimurium

(2007) Bradley L. Bearson et al.   MICROBIAL PATHOGENESIS