Synthesis, Biological Evaluation, and Molecular Simulation of Chalcones and Aurones as Selective MAO-B Inhibitors

Polyphenols bearing cinnamaldehyde scaffold showing cell growth inhibitory effects on the cisplatin-resistant A2780/Cis ovarian cancer cells

(2014) Soon Young Shin et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Development of potential selective and reversible pyrazoline based MAO-B inhibitors as MAO-B PET tracer precursors and reference substances for the early detection of Alzheimer’s disease

(2014) Catharina Neudorfer et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

α-Tetralone derivatives as inhibitors of monoamine oxidase

(2014) Lesetja J. Legoabe et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: Focus on modulation of CNS monoamine neurotransmitter release

(2014) John P.M. Finberg   PHARMACOLOGY & THERAPEUTICS

Sulfuretin-induced miR-30C selectively downregulates cyclin D1 and D2 and triggers cell death in human cancer cell lines

(2013) Suman Poudel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cardamonin Suppresses the Proliferation of Colon Cancer Cells by Promoting β-Catenin Degradation

(2013) Seoyoung Park et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Chromenylchalcones with inhibitory effects on monoamine oxidase B

(2013) Geunhyeong Jo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Selected furanochalcones as inhibitors of monoamine oxidase

(2013) Sarel J. Robinson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells

(2013) Sun Young Kim et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Assessment of the Antineoplastic Potential of Chalcones in Animal Models

(2013) B.I. Roman et al.   CURRENT MEDICINAL CHEMISTRY

Effect of xanthohumol and 8-prenylnaringenin on MCF-7 breast cancer cells oxidative stress and mitochondrial complexes expression

(2013) M. Mar Blanquer-Rosselló et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Molecular Modeling of p38α Mitogen-Activated Protein Kinase Inhibitors through 3D-QSAR and Molecular Dynamics Simulations

(2013) Hsin-Wen Chang et al.   Journal of Chemical Information and Modeling

Evaluation of selective human MAO inhibitory activities of some novel pyrazoline derivatives

(2013) Umut Salgın-Gökşen et al.   JOURNAL OF NEURAL TRANSMISSION

An update on amine oxidase inhibitors: Multifaceted drugs

(2013) Mee-Sook Song et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Identifying the Molecular Mechanics and Binding Dynamics Characteristics of Potent Inhibitors to HIV-1 Protease

(2012) Dechang Li et al.   Chemical Biology & Drug Design

Recent Advances in the Medicinal Chemistry of Aurones

(2012) R. Haudecoeur et al.   CURRENT MEDICINAL CHEMISTRY

In vitro inhibitory properties of ferrocene-substituted chalcones and aurones on bacterial and human cell cultures

(2012) Keshri Nath Tiwari et al.   DALTON TRANSACTIONS

Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus), Prevents Platelet Activation in Human Platelets

(2012) Ye-Ming Lee et al.   Evidence-based Complementary and Alternative Medicine

Prenylated chalcone xanthohumol associates with histones in breast cancer cells-a novel target identified by a monoclonal antibody

(2012) Ciska Wyns et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A quantum chemical study on the antioxidant properties of aureusidin and bracteatin

(2011) K. Senthil Kumar et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

Homoisoflavonoids: Natural Scaffolds with Potent and Selective Monoamine Oxidase-B Inhibition Properties

(2011) Nicoletta Desideri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sulfuretin attenuates allergic airway inflammation in mice

(2010) Mi-Young Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-inflammatory effects of sulfuretin from Rhus verniciflua Stokes via the induction of heme oxygenase-1 expression in murine macrophages

(2010) Dong-Sung Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Sulfuretin isolated from heartwood of Rhus verniciflua inhibits LPS-induced inducible nitric oxide synthase, cyclooxygenase-2, and pro-inflammatory cytokines expression via the down-regulation of NF-κB in RAW 264.7 murine macrophage cells

(2010) Ji-Sun Shin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Molecular and Mechanistic Properties of the Membrane-Bound Mitochondrial Monoamine Oxidases

(2009) Dale E. Edmondson et al.   BIOCHEMISTRY

Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity

(2009) Anastasia Detsi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chalcones: A Valid Scaffold for Monoamine Oxidases Inhibitors

(2009) Franco Chimenti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Determination of the Oligomeric States of Human and Rat Monoamine Oxidases in the Outer Mitochondrial Membrane and Octyl β-d-Glucopyranoside Micelles Using Pulsed Dipolar Electron Spin Resonance Spectroscopy†

(2008) Anup K. Upadhyay et al.   BIOCHEMISTRY

Analysis of Basic Clustering Algorithms for Numerical Estimation of Statistical Averages in Biomolecules

(2008) Ramu Anandakrishnan et al.   JOURNAL OF COMPUTATIONAL BIOLOGY