标题
Prospects in the Total Synthesis of Protein Therapeutics
作者
关键词
-
出版物
Chemical Biology & Drug Design
Volume 81, Issue 1, Pages 122-135
出版商
Wiley
发表日期
2012-12-19
DOI
10.1111/cbdd.12007
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Chemical Synthesis of an Erythropoietin Glycoform Containing a Complex-type Disialyloligosaccharide
- (2012) Masumi Murakami et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Total Synthesis of Homogeneous Antifreeze Glycopeptides and Glycoproteins
- (2012) Brendan L. Wilkinson et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Chemical Protein Synthesis by Chemoselective α-Ketoacid-Hydroxylamine (KAHA) Ligations with 5-Oxaproline
- (2012) Vijaya R. Pattabiraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Chemical Synthesis of Homogeneous Human Glycosyl-interferon-β That Exhibits Potent Antitumor Activity in Vivo
- (2012) Izumi Sakamoto et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Advances in Proline Ligation
- (2012) Steven D. Townsend et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis and Utility of β-Selenol-Phenylalanine for Native Chemical Ligation–Deselenization Chemistry
- (2012) Lara R. Malins et al. ORGANIC LETTERS
- Native Chemical Ligation at Glutamine
- (2012) Peter Siman et al. ORGANIC LETTERS
- Probing the stability of nonglycosylated wild-type erythropoietin protein via reiterative alanine ligations
- (2012) J. A. Brailsford et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Total Chemical Synthesis of a 304 Amino Acid K48-Linked Tetraubiquitin Protein
- (2011) K. S. Ajish Kumar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Chemical Synthesis of Ubiquitinated Peptides with Varying Lengths and Types of Ubiquitin Chains to Explore the Activity of Deubiquitinases
- (2011) Sudhir N. Bavikar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Convergent Chemical Synthesis of [Lysine24, 38, 83] Human Erythropoietin
- (2011) Suhuai Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Mechanism of the α-Ketoacid-Hydroxylamine Amide-Forming Ligation
- (2011) Ivano Pusterla et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Native Chemical Ligation Combined with Desulfurization and Deselenization: A General Strategy for Chemical Protein Synthesis
- (2011) Philip E. Dawson ISRAEL JOURNAL OF CHEMISTRY
- An Advance in Proline Ligation
- (2011) Shiying Shang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cancer immunotherapy comes of age
- (2011) Ira Mellman et al. NATURE
- Peptide Ligations Accelerated byN-Terminal Aspartate and Glutamate Residues
- (2011) Gemma L. Thomas et al. ORGANIC LETTERS
- Application of the logic of cysteine-free native chemical ligation to the synthesis of Human Parathyroid Hormone (hPTH)
- (2011) S. Shang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the Reach of Chemical Synthesis: Creation of a Mini-Pipeline from an Academic Laboratory
- (2010) Rebecca M. Wilson et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin
- (2010) Farid El Oualid et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Traceless Ligation of Cysteine Peptides Using Selective Deselenization
- (2010) Norman Metanis et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Invited reviewligation-Desulfurization: A powerful combination in the synthesis of peptides and glycopeptides
- (2010) Heike Rohde et al. BIOPOLYMERS
- Parathyroid Hormone and Bone Healing
- (2010) M. Ellegaard et al. CALCIFIED TISSUE INTERNATIONAL
- Protein Synthesis Assisted by Native Chemical Ligation at Leucine
- (2010) Ziv Harpaz et al. CHEMBIOCHEM
- Chemical synthesis of homogeneous glycopeptides and glycoproteins
- (2010) Yasuhiro Kajihara et al. CHEMICAL RECORD
- Chemical mutagenesis: selective post-expression interconversion of protein amino acid residues
- (2010) Justin M Chalker et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Post-translational modifications of protein biopharmaceuticals
- (2010) Gary Walsh DRUG DISCOVERY TODAY
- Biopharmaceutical benchmarks 2010
- (2010) Gary Walsh NATURE BIOTECHNOLOGY
- Development trends for human monoclonal antibody therapeutics
- (2010) Aaron L. Nelson et al. NATURE REVIEWS DRUG DISCOVERY
- Carbohydrate vaccines: developing sweet solutions to sticky situations?
- (2010) Rena D. Astronomo et al. NATURE REVIEWS DRUG DISCOVERY
- Highly Efficient and Chemoselective Peptide Ubiquitylation
- (2009) K. S. Ajish Kumar et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex-Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods
- (2009) Kiriko Hirano et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of homogeneous antifreeze glycopeptides via a ligation–desulfurisation strategy
- (2009) James Garner et al. CHEMICAL COMMUNICATIONS
- Phosphate-assisted peptide ligation
- (2009) Gemma L. Thomas et al. CHEMICAL COMMUNICATIONS
- Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins
- (2009) Richard J. Payne et al. CHEMICAL COMMUNICATIONS
- Efficient Substitution Reaction from Cysteine to the Serine Residue of Glycosylated Polypeptide: Repetitive Peptide Segment Ligation Strategy and the Synthesis of Glycosylated Tetracontapeptide Having Acid Labile Sialyl-TNAntigens
- (2009) Ryo Okamoto et al. JOURNAL OF ORGANIC CHEMISTRY
- Toward Homogeneous Erythropoietin: Chemical Synthesis of the Ala1−Gly28Glycopeptide Domain by “Alanine” Ligation
- (2009) Cindy Kan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Toward Homogeneous Erythropoietin: Fine Tuning of the C-Terminal Acyl Donor in the Chemical Synthesis of the Cys29−Gly77Glycopeptide Domain
- (2009) Yu Yuan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Toward Homogeneous Erythropoietin: Non-NCL-Based Chemical Synthesis of the Gln78−Arg166Glycopeptide Domain
- (2009) Zhongping Tan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dual Native Chemical Ligation at Lysine
- (2009) Renliang Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent departures in the synthesis of peptides and glycopeptides
- (2009) Cindy Kan et al. TETRAHEDRON
- Expressed Protein Ligation (EPL) in the Study of Signal Transduction, Ion Conduction, And Chromatin Biology
- (2008) Robert R. Flavell et al. ACCOUNTS OF CHEMICAL RESEARCH
- Cysteine-Free Peptide and Glycopeptide Ligation by Direct Aminolysis
- (2008) Richard J. Payne et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Native Chemical Ligation at Valine: A Contribution to Peptide and Glycopeptide Synthesis
- (2008) Jin Chen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Native Chemical Ligation at Valine
- (2008) Christian Haase et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Glycoprotein Synthesis: An Update
- (2008) David P. Gamblin et al. CHEMICAL REVIEWS
- Total chemical synthesis of proteins
- (2008) Stephen B. H. Kent CHEMICAL SOCIETY REVIEWS
- The Function of the Human Interferon- 1a Glycan Determined in Vivo
- (2008) L. Dissing-Olesen et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Sugar-Assisted Glycopeptide Ligation with Complex Oligosaccharides: Scope and Limitations
- (2008) Clay S. Bennett et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Calcium homeostasis: Reassessment of the actions of parathyroid hormone
- (2007) Roy V. Talmage et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started