期刊
CHEMICAL & PHARMACEUTICAL BULLETIN
卷 56, 期 12, 页码 1725-1728出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.56.1725
关键词
Cleistocalyx operculatus; Myrtaceae; anti oxidant; flavonoid
资金
- Hanoi University of Pharmacy, Hanoi, Vietnam and Gyeongbuk Regional Innovation Agency (2007), Korea
Four new Havonoids, 3'-formyl-4',6',4-trihydroxy-2'-methoxy-5'-methylchalcone (1), 3'-formyl-6',4-dihy- roxy-2'-methoxy-5'-methylchalcone 4'-O-beta-D-glucopyranoside (2), (2S)-8-formyl-6-methylnaringenin (3), and (2S)-8-formyl-6-methylnaringenin 7-O-beta-D-glucopyranoside (4) were isolated from the buds of Cleislocalyx operculatus (Myrtaceae). The structures of the new metabolites (1-4) were determined on the basic of spectroscopic analyses including 2 dimensional NMR. Compounds I and 3 exhibited 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity with IC50 values of 22.8 and 27.1 mu M, respectively.
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