Cyanide-free Enantioselective Synthesis of Nitriles: Synthetic Proof of a Biocatalytic Concept and Mechanistic Insights

Catalytic Asymmetric Protonation of Silyl Ketene Imines

(2013) Joyram Guin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Old Yellow Enzyme-mediated reduction of β-cyano-α,β-unsaturated esters for the synthesis of chiral building blocks: stereochemical analysis of the reaction

(2013) Elisabetta Brenna et al.   Catalysis Science & Technology

Why Is the Oxidation State of Iron Crucial for the Activity of Heme-Dependent Aldoxime Dehydratase? A QM/MM Study

(2012) Rong-Zhen Liao et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Catalytic Asymmetric Synthesis of Secondary Nitriles via Stereoconvergent Negishi Arylations and Alkenylations of Racemic α-Bromonitriles

(2012) Junwon Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient, Chemoenzymatic Process for Manufacture of the Boceprevir Bicyclic [3.1.0]Proline Intermediate Based on Amine Oxidase-Catalyzed Desymmetrization

(2012) Tao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Presenting your structures: theCCP4mgmolecular-graphics software

(2011) S. McNicholas et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

(2010) Fraser F. Fleming et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Enantioselective Construction of β-Quaternary Carbons via a Conjugate Addition of Cyanide to β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds

(2010) Yuta Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preparation of Saxagliptin, a Novel DPP-IV Inhibitor

(2009) Scott A. Savage et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Dinuclear {(salen)Al} Complexes Display Expanded Scope in the Conjugate Cyanation of α,β-Unsaturated Imides

(2008) Clément Mazet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric bioreduction of α,β-unsaturated nitriles and ketones

(2008) Birgit Kosjek et al.   TETRAHEDRON-ASYMMETRY