Telomerization of Myrcene and Catalyst Separation by Thermomorphic Solvent Systems

Telomerization of common petrochemical 1,3-dienes such as butadiene and isoprene have long been successful with different nucleophiles; however, the telomerization of the C(10) hydrocarbon myrcene was not known until now. Herein, the first telomerization of the monoterpene myrcene with diethyl, amine is discussed, which provides an atom-economical way of generating C(10) amines in a single step. Variation of the palladium precursors and phosphorous ligands and optimization of solvent and additives led to the optimum catalyst system [Pd(MeCN)(4)](BF(4))(2)/PPh(3). By using a thermomorphic solvent system, the Pd complex can be easily separated with low leaching values.