Delivery of Antibody Mimics into Mammalian Cells via Anthrax Toxin Protective Antigen

Targeting allosteric regulatory modules in oncoproteins: “Drugging the Undruggable”

(2015)   Oncotarget

Monitoring Endocytic Trafficking of Anthrax Lethal Factor by Precise and Quantitative Protein Labeling

(2014) Siqi Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineered knottin peptide enables noninvasive optical imaging of intracranial medulloblastoma

(2013) Sarah J. Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific Inhibition of Caspase-3 by a Competitive DARPin: Molecular Mimicry between Native and Designed Inhibitors

(2013) Thilo Schroeder et al.   STRUCTURE

Anthrax Toxin-Mediated Delivery of the Pseudomonas Exotoxin A Enzymatic Domain to the Cytosol of Tumor Cells via Cleavable Ubiquitin Fusions

(2013) C. Bachran et al.   mBio

Designed Ankyrin Repeat Proteins (DARPins) as Novel Isoform-Specific Intracellular Inhibitors of c-Jun N-Terminal Kinases

(2012) Petra Parizek et al.   ACS Chemical Biology

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Structural insights for engineering binding proteins based on non-antibody scaffolds

(2012) Ryan N Gilbreth et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein Thioester Synthesis Enabled by Sortase

(2012) Jingjing J. Ling et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

(2012) Jakob von Moltke et al.   NATURE

Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries

(2012) L. Kummer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography

(2012) K. Mandal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis

(2011) Florian Grebien et al.   CELL

Tailoring nanocarriers for intracellular protein delivery

(2011) Zhen Gu et al.   CHEMICAL SOCIETY REVIEWS

Targeting antibodies to the cytoplasm

(2011) Andrea L.J. Marschall et al.   mAbs

Monitored whole gene in vitro evolution of an anti-hRaf-1 affibody molecule towards increased binding affinity

(2011) Sebastian Grimm et al.   New Biotechnology

A general strategy for the evolution of bond-forming enzymes using yeast display

(2011) I. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potent Delivery of Functional Proteins into Mammalian Cellsin Vitroandin VivoUsing a Supercharged Protein

(2010) James J. Cronican et al.   ACS Chemical Biology

Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras

(2010) Irene Zornetta et al.   CELLULAR MICROBIOLOGY

Design of next-generation protein therapeutics

(2010) Justin Caravella et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Affibody molecules: Engineered proteins for therapeutic, diagnostic and biotechnological applications

(2010) J. Löfblom et al.   FEBS LETTERS

Convergent Potency of Internalized Gelonin Immunotoxins across Varied Cell Lines, Antigens, and Targeting Moieties

(2010) Christopher M. Pirie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

(2010) John Wojcik et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

(2009) Frederic Heitz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Functional Protein Delivery into Neurons Using Polymeric Nanoparticles

(2009) Linda Hasadsri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes

(2009) Alexander F. Kintzer et al.   JOURNAL OF MOLECULAR BIOLOGY

Selection and characterization of Affibody® ligands to the transcription factor c-Jun

(2008) Emma Lundberg et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation

(2008) J. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On The Biomedical Promise of Cell Penetrating Peptides: Limits Versus Prospects

(2007) Christina Foerg et al.   JOURNAL OF PHARMACEUTICAL SCIENCES