The Development of Antimicrobial α-AApeptides that Suppress Proinflammatory Immune Responses

Lipidated Cyclic γ-AApeptides Display Both Antimicrobial and Anti-inflammatory Activity

(2013) Yaqiong Li et al.   ACS Chemical Biology

Toll-like receptors as therapeutic targets for autoimmune connective tissue diseases

(2013) Jing Li et al.   PHARMACOLOGY & THERAPEUTICS

Identification of Synthetic Host Defense Peptide Mimics That Exert Dual Antimicrobial and Anti-Inflammatory Activities

(2012) Abhigyan Som et al.   Clinical and Vaccine Immunology

Lipo-γ-AApeptides as a New Class of Potent and Broad-Spectrum Antimicrobial Agents

(2012) Youhong Niu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthetic Mimics of Antimicrobial Peptides with Immunomodulatory Responses

(2012) Hitesh D. Thaker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Poly(ethylene imine)s as Antimicrobial Agents with Selective Activity

(2012) Katherine A. Gibney et al.   MACROMOLECULAR BIOSCIENCE

Design and synthesis of unprecedented cyclic γ-AApeptides for antimicrobial development

(2012) Haifan Wu et al.   Chemical Science

Lipidated Peptidomimetics with Improved Antimicrobial Activity

(2012) Yaogang Hu et al.   ACS Medicinal Chemistry Letters

Efficacy of Antimicrobial Peptoids against Mycobacterium tuberculosis

(2011) Rinki Kapoor et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial Peptoids Are Effective against Pseudomonas aeruginosa Biofilms

(2011) Rinki Kapoor et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design and synthesis of AApeptides: A new class of peptide mimics

(2011) Yaogang Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

An inhibitor of cyclin-dependent kinases suppresses TLR signaling and increases the susceptibility of cancer patients to herpes viridae

(2011) Mustapha Zoubir et al.   CELL CYCLE

Non-hemolytic α-AApeptides as antimicrobial peptidomimetics

(2011) Shruti Padhee et al.   CHEMICAL COMMUNICATIONS

Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity

(2011) Youhong Niu et al.   CHEMICAL COMMUNICATIONS

A Comparison of Linear and Cyclic Peptoid Oligomers as Potent Antimicrobial Agents

(2011) Mia Lace Huang et al.   ChemMedChem

Small-Molecule Inhibitors of the TLR3/dsRNA Complex

(2011) Kui Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

(2011) Lakshmi Raj et al.   NATURE

Short Alkylated Peptoid Mimics of Antimicrobial Lipopeptides

(2010) Nathaniel P. Chongsiriwatana et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Polyelectrolyte Multilayers Fabricated from Antifungal β-Peptides: Design of Surfaces that Exhibit Antifungal Activity Against Candida albicans

(2010) Amy J. Karlsson et al.   BIOMACROMOLECULES

Antimicrobial, Hemolytic, and Cytotoxic Activities of β-Peptoid-Peptide Hybrid Oligomers: Improved Properties Compared to Natural AMPs

(2010) Christian A. Olsen et al.   CHEMBIOCHEM

Activity of antimicrobial peptide mimetics in the oral cavity: II. Activity against periopathogenic biofilms and anti-inflammatory activity

(2010) J. Hua et al.   Molecular Oral Microbiology

Activity of antimicrobial peptide mimetics in the oral cavity: I. Activity against biofilms of Candida albicans

(2010) J. Hua et al.   Molecular Oral Microbiology

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications

(2009) Gregory N. Tew et al.   ACCOUNTS OF CHEMICAL RESEARCH

Effect of Sequence and Structural Properties on 14-Helical β-Peptide Activity againstCandida albicansPlanktonic Cells and Biofilms

(2009) Amy J. Karlsson et al.   ACS Chemical Biology

Consequences of Isostructural Main-Chain Modifications for the Design of Antimicrobial Foldamers: Helical Mimics of Host-Defense Peptides Based on a Heterogeneous Amide/Urea Backbone

(2009) Paul Claudon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evidence that opioids may have toll-like receptor 4 and MD-2 effects

(2009) Mark R. Hutchinson et al.   BRAIN BEHAVIOR AND IMMUNITY

Synthetic Mimics of Antimicrobial Peptides-A Versatile Ring-Opening Metathesis Polymerization Based Platform for the Synthesis of Selective Antibacterial and Cell-Penetrating Polymers

(2009) Karen Lienkamp et al.   CHEMISTRY-A EUROPEAN JOURNAL

De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers

(2009) S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent Progress in the Discovery of Macrocyclic Compounds as Potential Anti-Infective Therapeutics

(2008) D. Obrecht et al.   CURRENT MEDICINAL CHEMISTRY

Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)

(2008) Mark R. Hutchinson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides

(2008) N. P. Chongsiriwatana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA