In Vivo Incorporation of Non-canonical Amino Acids by Using the Chemical Aminoacylation Strategy: A Broadly Applicable Mechanistic Tool

Unnatural Amino Acids as Probes of Ligand-Receptor Interactions and Their Conformational Consequences

(2013) Stephan A. Pless et al.   Annual Review of Pharmacology and Toxicology

Detection of Dihydrofolate Reductase Conformational Change by FRET Using Two Fluorescent Amino Acids

(2013) Shengxi Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Cation−π Interaction

(2012) Dennis A. Dougherty   ACCOUNTS OF CHEMICAL RESEARCH

Variations in Binding Among Several Agonists at Two Stoichiometries of the Neuronal, α4β2 Nicotinic Receptor

(2012) Ximena Da Silva Tavares et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain

(2012) Pierre-Jean Corringer et al.   STRUCTURE

Dissecting the Functions of Conserved Prolines within Transmembrane Helices of the D2 Dopamine Receptor

(2011) Ethan B. Van Arnam et al.   ACS Chemical Biology

Evidence for an Extended Hydrogen Bond Network in the Binding Site of the Nicotinic Receptor

(2011) Angela P. Blum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flexizymes for genetic code reprogramming

(2011) Yuki Goto et al.   Nature Protocols

Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels

(2011) Stephan A. Pless et al.   Nature Communications

Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications

(2010) Jeremiah A Johnson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chemical Scale Studies of the Phe-Pro Conserved Motif in the Cys Loop of Cys Loop Receptors

(2010) Walrati Limapichat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon

(2010) Travis S. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Photochemical Proteolysis of an Unstructured Linker of the GABAAR Extracellular Domain Prevents GABA but Not Pentobarbital Activation

(2010) A. P. Hanek et al.   MOLECULAR PHARMACOLOGY

Preparation of Translationally Competent tRNA by Direct Chemical Acylation

(2010) Noah H. Duffy et al.   ORGANIC LETTERS

Nicotinic pharmacophore: The pyridine N of nicotine and carbonyl of acetylcholine hydrogen bond across a subunit interface to a backbone NH

(2010) A. P. Blum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Molecule Imaging of a Fluorescent Unnatural Amino Acid Incorporated Into Nicotinic Receptors

(2009) Rigo Pantoja et al.   BIOPHYSICAL JOURNAL

Probing the Role of Backbone Hydrogen Bonding in a Critical β Sheet of the Extracellular Domain of a Cys-Loop Receptor

(2009) Kristin R. Gleitsman et al.   CHEMBIOCHEM

An electrostatic interaction between TEA and an introduced pore aromatic drives spring-in-the-door inactivation inShakerpotassium channels

(2009) Christopher A. Ahern et al.   JOURNAL OF GENERAL PHYSIOLOGY

A Selenide-Based Approach to Photochemical Cleavage of Peptide and Protein Backbones at Engineered Backbone Esters

(2009) Amy L. Eastwood et al.   JOURNAL OF ORGANIC CHEMISTRY

Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues

(2009) Pierre-Jean Corringer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nicotine binding to brain receptors requires a strong cation–π interaction

(2009) Xinan Xiu et al.   NATURE

Probing the role of the cation-  interaction in the binding sites of GPCRs using unnatural amino acids

(2009) M. M. Torrice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Hydrogen Bond in Loop A Is Critical for the Binding and Function of the 5-HT3Receptor†

(2008) Kerry L. Price et al.   BIOCHEMISTRY

Cys-Loop Neuroreceptors: Structure to the Rescue?

(2008) Dennis A. Dougherty   CHEMICAL REVIEWS

An Intersubunit Hydrogen Bond in the Nicotinic Acetylcholine Receptor That Contributes to Channel Gating

(2008) Kristin Rule Gleitsman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Stereochemical Test of a Proposed Structural Feature of the Nicotinic Acetylcholine Receptor

(2008) Ariele P. Hanek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Addition of an α-Hydroxy Acid to the Genetic Code of Bacteria

(2007) Jiantao Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels

(2007) Christopher A. Ahern et al.   CIRCULATION RESEARCH