A Single Mutation at the Ferredoxin Binding Site of P450 Vdh Enables Efficient Biocatalytic Production of 25-Hydroxyvitamin D3

Structural Basis for Effector Control and Redox Partner Recognition in Cytochrome P450

(2013) S. Tripathi et al.   SCIENCE

Tailoring an alien ferredoxin to support native-like P450 monooxygenase activity

(2012) Stephen G. Bell et al.   CHEMICAL COMMUNICATIONS

Structure-guided mutagenesis for the improvement of substrate specificity ofBacillus megateriumglucose 1-dehydrogenase IV

(2012) Taiki Nishioka et al.   FEBS Journal

Permeabilization induced by lipid II-targeting lantibiotic nisin and its effect on the bioconversion of vitamin D3 to 25-hydroxyvitamin D3 by Rhodococcus erythropolis

(2011) Noriko Imoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

P450BM3(CYP102A1): connecting the dots

(2011) Christopher J. C. Whitehouse et al.   CHEMICAL SOCIETY REVIEWS

Cytochrome P450 monooxygenases: an update on perspectives for synthetic application

(2011) Vlada B. Urlacher et al.   TRENDS IN BIOTECHNOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

P450cam Visits an Open Conformation in the Absence of Substrate,

(2010) Young-Tae Lee et al.   BIOCHEMISTRY

Bioconversion of vitamin D to its active form by bacterial or mammalian cytochrome P450

(2010) Toshiyuki Sakaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Three-step hydroxylation of vitamin D3 by a genetically engineered CYP105A1

(2010) Keiko Hayashi et al.   FEBS Journal

Structural Evidence for Enhancement of Sequential Vitamin D3Hydroxylation Activities by Directed Evolution of Cytochrome P450 Vitamin D3Hydroxylase

(2010) Yoshiaki Yasutake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Characterization of a Class I P450 Electron Transfer System fromNovosphingobium aromaticivoransDSM12444

(2010) Wen Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Purification, characterization, and directed evolution study of a vitamin D 3 hydroxylase from Pseudonocardia autotrophica

(2009) Yoshikazu Fujii et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Efficient Biotransformations UsingEscherichia coliwithtolCacrABMutations Expressing Cytochrome P450 Genes

(2009) Tadashi FUJII et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes

(2009) Paul R. Ortiz de Montellano   CHEMICAL REVIEWS

Investigating the Structural Plasticity of a Cytochrome P450

(2009) Carmelinda Savino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein recognition in ferredoxin–P450 electron transfer in the class I CYP199A2 system from Rhodopseudomonas palustris

(2009) Stephen G. Bell et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy

(2009) Valeria Tiranti et al.   NATURE MEDICINE

Novel synthesis of 1α,25-dihydroxy-19-norvitamin D from 25-hydroxyvitamin D

(2009) Asako Toyoda et al.   TETRAHEDRON

Structure-Based Design of a Highly Active Vitamin D Hydroxylase fromStreptomyces griseolusCYP105A1†‡

(2008) Keiko Hayashi et al.   BIOCHEMISTRY

Heme-iron oxygenases: powerful industrial biocatalysts?

(2008) Mattijs K Julsing et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Solution NMR Structure of Putidaredoxin–Cytochrome P450cam Complex via a Combined Residual Dipolar Coupling–Spin Labeling Approach Suggests a Role for Trp106 of Putidaredoxin in Complex Formation

(2008) Wei Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Analysis of CYP2R1 in Complex with Vitamin D3

(2008) Natallia Strushkevich et al.   JOURNAL OF MOLECULAR BIOLOGY