Voltage-gated sodium channels

Effects of the antianginal drug, ranolazine, on the brain sodium channel NaV1.2 and its modulation by extracellular protons

(2013) CH Peters et al.   BRITISH JOURNAL OF PHARMACOLOGY

A thermoprotective role of the sodium channel β1 subunit is lost with the β1(C121W) mutation

(2012) Csilla Egri et al.   EPILEPSIA

The Hodgkin-Huxley Heritage: From Channels to Circuits

(2012) W. A. Catterall et al.   JOURNAL OF NEUROSCIENCE

China must provide education on HIV

(2012) Jian Zhang et al.   NATURE

SCN1A splice variants exhibit divergent sensitivity to commonly used antiepileptic drugs

(2011) Christopher H. Thompson et al.   EPILEPSIA

Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels

(2010) Hai Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Lidocaine, Carbamazepine, and Imipramine Have Partially Overlapping Binding Sites and Additive Inhibitory Effect on Neuronal Na+ Channels

(2010) Ya-Chin Yang et al.   ANESTHESIOLOGY

Ranolazine selectively blocks persistent current evoked by epilepsy-associated NaV1.1 mutations

(2010) Kristopher M Kahlig et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sodium channel SCN1A and epilepsy: Mutations and mechanisms

(2010) Andrew Escayg et al.   EPILEPSIA

Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus

(2010) Verena C. Wimmer et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficacy Loss of the Anticonvulsant Carbamazepine in Mice Lacking Sodium Channel   Subunits via Paradoxical Effects on Persistent Sodium Currents

(2010) M. Uebachs et al.   JOURNAL OF NEUROSCIENCE

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

Molecular Model of Anticonvulsant Drug Binding to the Voltage-Gated Sodium Channel Inner Pore

(2010) G. M. Lipkind et al.   MOLECULAR PHARMACOLOGY

Fast- or Slow-inactivated State Preference of Na+ Channel Inhibitors: A Simulation and Experimental Study

(2010) Robert Karoly et al.   PLoS Computational Biology

Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine

(2008) P. L. Sheets et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS