Review
Medicine, General & Internal
Marialuisa Zedde, Ilaria Grisendi, Francesca Romana Pezzella, Manuela Napoli, Claudio Moratti, Franco Valzania, Rosario Pascarella
Summary: Acute onset quadriplegia is a rare vascular syndrome that mainly affects the cervical and upper thoracic spinal cord, as well as occasionally the brainstem. This study collected and reviewed the clinical, neuroanatomical, and neuroimaging features of ischemic stroke locations associated with quadriplegia. Two clinical examples were provided to offer practical suggestions for managing these cases.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Neuroimaging
Mira Liu, Niloufar Saadat, Yong Ik Jeong, Steven Roth, Marek Niekrasz, Timothy Carroll, Gregory A. Christoforidis
Summary: This study suggests that perfusion can be increased in acute ischemic stroke patients with the use of norepinephrine and hydralazine. The increase in perfusion depends on the degree of collateralization and the specific territory being examined, with evidence of possible vascular steal.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Neuroimaging
Niloufar Saadat, Gregory A. Christoforidis, Yong Ik Jeong, Mira Liu, Alexey Dimov, Steven Roth, Marek Niekrasz, Sameer A. Ansari, Timothy Carroll
Summary: The combination therapy of norepinephrine and hydralazine administered in the acute phase of ischemic stroke can mitigate infarct evolution in subjects with poor collateral recruitment only. Measured infarct growth was significantly lower than predicted, indicating a potential benefit of this treatment approach. No evidence of cerebral hemorrhage or posterior reversible encephalopathy syndrome was found.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2021)
Article
Neuroimaging
Ryan A. Rava, Kenneth Snyder, Maxim Mokin, Muhammad Waqas, Xiaoliang Zhang, Alexander R. Podgorsak, Ariana B. Allman, Jillian Senko, Mohammad Mahdi Shiraz Bhurwani, Yiemeng Hoi, Jason M. Davies, Elad Levy, Adnan H. Siddiqui, Ciprian N. Ionita
Summary: This study aimed to compare the predicted infarct and penumbra volumes from different CTP software with follow-up FLAIR MRI in patients with acute ischemic stroke, finding that Sphere was the most accurate in infarct assessment for patients who had intervention, while Vitrea was the most accurate in penumbra assessment for patients who were treated conservatively.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Siri af Buren, Annika Kits, Lucas Lonn, Francesca De Luca, Tim Sprenger, Stefan Skare, Anna Falk Delgado
Summary: The study aimed to investigate the diagnostic performance of fast multicontrast echo-planar MRI (EPIMix) in detecting ischemic lesions. The results showed that EPIMix was comparable to routine clinical MRI in diagnosing acute ischemic stroke, with high sensitivity and specificity.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Clinical Neurology
Simone Beretta, Francesca Iannuzzi, Susanna Diamanti, Elisa Bianchi, Luca D'Urbano, Colella Elisa, Alban Rugova, Carlo Morotti Colleoni, Ettore Beghi, Paolo Bonfanti, Carlo Ferrarese
Summary: This study investigated the phenotype of stroke patients with and without COVID-19 infection and their impact on in-hospital mortality. The study found that COVID+ stroke patients required more respiratory support and had a higher in-hospital mortality rate. Symptomatic interstitial pneumonia was identified as the major driver of mortality in COVID+ stroke patients.
NEUROLOGICAL SCIENCES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kye Jin Park, Ji-Yeon Suh, Changhoe Heo, Miyeon Kim, Jin Hee Baek, Jeong Kon Kim
Summary: HyperO(2)Delta R-1 can accurately identify histological infarction in acute stroke. It increases in the infarct area, while ADC decreases in the non-ischemic area. Areas with HyperO(2)Delta R-1 values higher than 0.04 s(-1) are strongly correlated with histological cell death.
KOREAN JOURNAL OF RADIOLOGY
(2022)
Article
Clinical Neurology
Patrick M. Fisher, Simon S. Albrechtsen, Vardan Nersesjan, Moshgan Amiri, Daniel Kondziella
Summary: This study investigates the functional connectivity of a middle-aged man after hemispherectomy, revealing increased between-network connectivity in the preserved hemisphere. This suggests that the brain can reorganize its connections to restore consciousness and cognitive functions after the loss of one hemisphere.
FRONTIERS IN NEUROLOGY
(2022)
Article
Multidisciplinary Sciences
Pishoy Gouda, Anamaria Savu, Kevin R. Bainey, Padma Kaul, Robert C. Welsh
Summary: Residual cardiovascular risk following acute coronary syndrome is high, especially with comorbidities like heart failure, hypertension, renal disease, and diabetes. Increased burden of comorbidities is associated with a higher risk of major adverse cardiovascular events, highlighting the need for aggressive therapies to reduce risk.
Article
Neuroimaging
Michael S. Stringer, Anna K. Heye, Paul A. Armitage, Francesca Chappell, Maria del C. Valdes Hernandez, Stephen D. J. Makin, Eleni Sakka, Michael J. Thrippleton, Joanna M. Wardlaw
Summary: The study showed that there is an increase in subtle blood-brain barrier permeability in small vessel disease. With the severity of white matter hyperintensity increasing, the permeability-surface area product increased in grey and normal-appearing white matter. Additionally, patients with more severe white matter hyperintensity had lower blood plasma volume in affected white matter, but higher in normal-appearing white matter.
NEUROIMAGE-CLINICAL
(2021)
Review
Clinical Neurology
Yanjie Huang, Zheng Xiao
Summary: Albumin therapy does not show long-term neurological benefits for patients with ischemic stroke, and patients are more likely to experience pulmonary edema and other complications after treatment, highlighting the need for cautious administration of albumin therapy in acute ischemic stroke cases.
NEUROLOGICAL SCIENCES
(2021)
Article
Medicine, General & Internal
Salman Al Jerdi, Naveed Akhtar, Ziyad Mahfoud, Saadat Kamran, Ashfaq Shuaib
Summary: The study aims to compare the long-term outcomes of acute ischemic stroke patients in the Middle-Eastern population. The results indicate that previous cerebrovascular/cardiovascular diseases significantly increase the risk of major cardiovascular events and early mortality.
Article
Clinical Neurology
Benjamin Vanderschelden, Fareshte Erani, Jennifer Wu, Adam de Havenon, Ramesh Srinivasan, Steven C. Cramer
Summary: This study demonstrates that EEG-based measures of neural function significantly improve the prediction of behavioral deficits in acute stroke patients, suggesting that EEG can provide valuable information for the treatment and rehabilitation of acute stroke.
Article
Urology & Nephrology
Wen-Yi Huang, Chun-Wei Chang, Kuan-Hsing Chen, Chien-Hung Chang, Hsiu-Chuan Wu, Kuo-Hsuan Chang
Summary: The incidence of ischemic stroke is higher in patients with nephrotic syndrome compared to the general population. This study aimed to examine the clinical manifestations of acute ischemic stroke in patients with and without nephrotic syndrome. The results showed that nephrotic syndrome was associated with a higher risk of functional dependence following ischemic stroke, particularly in certain stroke subtypes.
Article
Cardiac & Cardiovascular Systems
Toshiaki Suzuki, Yu Kataoka, Masayuki Shiozawa, Kensuke Morris, Eri Kiyoshige, Kunihiro Nishimura, Kota Murai, Kenichiro Sawada, Takamasa Iwai, Hideo Matama, Satoshi Honda, Masashi Fujino, Shuichi Yoneda, Kensuke Takagi, Fumiyuki Otsuka, Yasuhide Asaumi, Masatoshi Koga, Masafumi Ihara, Kazunori Toyoda, Kenichi Tsujita, Teruo Noguchi
Summary: Acute myocardial infarction (AMI) rarely occurs after acute stroke. The Heart-brain team approach has the potential to manage this poststroke cardiovascular complication. However, the clinical outcomes of AMI complicating acute stroke (AMI-CAS) with the heart-brain team approach have not been characterized. This study investigated the cardiovascular outcomes in patients with AMI-CAS managed by a heart-brain team.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)