Article
Geriatrics & Gerontology
Lea Chauveau, Elizabeth Kuhn, Cassandre Palix, Francesca Felisatti, Valentin Ourry, Vincent de La Sayette, Gael Chetelat, Robin de Flores
Summary: Studying the subregions of the medial temporal lobe is crucial for distinguishing age-related changes from Alzheimer's disease, with the findings highlighting the significant role of these subregions in cognitive functioning.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Clinical Neurology
Yuanzhi Xu, Ahmed Mohyeldin, Maximiliano Alberto Nunez, Ayoze Doniz-Gonzalez, Vera Vigo, Aaron A. Cohen-Gadol, Juan C. Fernandez-Miranda
Summary: The authors investigated the microvascular anatomy of the hippocampus and its implications for medial temporal tumor surgery, revealing the anatomical variability of the arterial supply and venous drainage of the hippocampus. The study found rich anastomoses between hippocampal arteries and highlighted the importance of understanding the vascular variability and network of the hippocampus for surgery in this region, including anterior temporal lobectomy with amygdalohippocampectomy and transsylvian selective amygdalohippocampectomy.
JOURNAL OF NEUROSURGERY
(2021)
Article
Neurosciences
C. Bodin, A. Pron, M. Le Mao, J. Regis, P. Belin, O. Coulon
Summary: The study reveals that plis de passage (PPs) can be identified as landmarks from the geometry of the STS walls, with their depth related to white-matter connectivity. These findings propose new hypotheses regarding the spatial organization of PPs, the relationship between cortical anatomy and structural connectivity, and the potential role of PPs in regional functional organization.
Article
Neurosciences
Robin de Flores, Sandhitsu R. Das, Long Xie, Laura E. M. Wisse, Xueying Lyu, Preya Shah, Paul A. Yushkevich, David A. Wolk
Summary: This study reveals the relationship between the medial temporal lobe and the anterior-temporal and posterior-medial networks, and explores the vulnerability of these networks to proteinopathies in Alzheimer's disease. The results show that the atrophy of distinct subregions in the medial temporal lobe propagates differently within the anterior-temporal and posterior-medial networks. Additionally, these networks are differentially associated with relative tau and amyloid burden.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
William D. Hopkins, Oliver Coulon, Adrien Meguerditchian, Nicky Staes, Chet C. Sherwood, Steven J. Schapiro, Jean-Francois Mangin, Brenda Bradley
Summary: This study examined the role of genetic factors in individual variation in superior temporal sulcus (STS) morphology in chimpanzees. The results showed significant correlations between single nucleotide polymorphisms in the KIAA0319 and AVPR1A genes and STS depth and lateralization, but no significant effects on surface area and depth measures for the central sulcus. The overall findings suggest that genetic factors contribute to a small to moderate amount of variation in STS morphology in chimpanzees.
Article
Behavioral Sciences
Bohee Lee, June Sic Kim, Chun Kee Chung
Summary: Working memory is crucial for goal-directed behavior, and the frontoparietal network and medial temporal lobe play important roles in working memory. Through intracranial electroencephalography recording, it was found that low-frequency power in the frontal lobe and medial temporal lobe increased and sustained throughout the working memory task, while parietal alpha power peaked during memory operation. Furthermore, there was a positive correlation in the alpha band between the medial temporal lobe and the parietal lobe during memory operation.
Article
Biochemistry & Molecular Biology
Kyle Rupp, Jasmine L. Hect, Madison Remick, Avniel Ghuman, Bharath Chandrasekaran, Lori L. Holt, Taylor J. Abel
Summary: The ability to recognize abstract features of voice during auditory perception is a complex task. Voice selectivity increases along the auditory hierarchy from supratemporal plane (STP) to the superior temporal gyrus (STG) and superior temporal sulcus (STS). Voice can be accurately decoded from human auditory cortical activity, even without linguistic content. Encoding models demonstrate that voice encoding in STG/STS is best explained by voice category and acoustics, while STP responses are primarily accounted for by acoustic features.
Article
Medicine, General & Internal
Xiao-Ming Yan, Cui-Ping Xu, Yu-Ping Wang, Kai Ma, Tao Yu, Xiao-Hua Zhang, Xi Zhang, Run-Shi Gao, Guo-Jun Zhang, Yong-Jie Li
Summary: Patients with medial temporal lobe seizures had more favorable surgical outcomes and distinct SEEG features compared to patients with lateral temporal lobe seizures.
CHINESE MEDICAL JOURNAL
(2021)
Article
Clinical Neurology
Cedric Dusanter, Marion Houot, Marie Mere, Marisa Denos, Severine Samson, Bastien Herlin, Vincent Navarro, Sophie Dupont
Summary: The aim of this study was to evaluate the specific effects of antiseizure medications (ASMs) on cognition in a group of refractory patients with epilepsy. The results showed that the type and number of ASMs had a significant impact on cognition, especially topiramate (TPM) and sodium valproate (VPA). Based on the findings, it is recommended to reduce the total number of drugs received and avoid medications with unfavorable cognitive profiles.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Neurosciences
Johannes Rennig, Michael S. Beauchamp
Summary: Regions of the human posterior superior temporal gyrus and sulcus are responsible for processing visual and auditory speech, and successful integration of visual and auditory speech produces a characteristic neural signature that benefits the comprehension of noisy auditory speech.
Review
Clinical Neurology
Nadim Jaafar, Amar Bhatt, Alexandra Eid, Mohamad Z. Koubeissi
Summary: Some surgical failures after temporal lobe epilepsy surgery may be caused by the presence of extratemporal epileptogenic zones, particularly in the medial parietal lobe. Seizures originating from this area may not cause obvious symptoms before spreading to the temporal lobe.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Paul A. Yushkevich, Monica Munoz Lopez, Maria Mercedes Iniguez de Onzono Martin, Ranjit Ittyerah, Sydney Lim, Sadhana Ravikumar, Madigan L. Bedard, Stephen Pickup, Weixia Liu, Jiancong Wang, Ling Yu Hung, Jade Lasserve, Nicolas Vergnet, Long Xie, Mengjin Dong, Salena Cui, Lauren McCollum, John L. Robinson, Theresa Schuck, Robin de Flores, Murray Grossman, M. Dylan Tisdall, Karthik Prabhakaran, Gabor Mizsei, Sandhitsu R. Das, Emilio Artacho-Perula, Mari'a Del Mar Arroyo Jimenez, Mari'a Pilar Marcos Raba, Francisco Javier Molina Romero, Sandra Cebada Sanchez, Jose Carlos Delgado Gonzalez, Carlos De la Rosa-Prieto, Marta Corcoles Parada, Edward B. Lee, John Q. Trojanowski, Daniel T. Ohm, Laura E. M. Wisse, David A. Wolk, David J. Irwin, Ricardo Insausti
Summary: This study utilized ex vivo MRI and dense serial histological imaging to construct three-dimensional quantitative maps of neurofibrillary tangle burden in the medial temporal lobe, revealing significant variation along different anatomical regions. The findings provide valuable insights into the distribution of this neurodegenerative pathology and may support the development and validation of neuroimaging biomarkers.
Article
Neurosciences
Justyna O. Ekert, Andrea Gajardo-Vidal, Diego L. Lorca-Puls, Thomas M. H. Hope, Fred Dick, Jennifer T. Crinion, David W. Green, Cathy J. Price
Summary: Previous studies have shown that the left posterior superior temporal sulcus (pSTS) and left temporo-parietal junction (TPJ) both contribute to phonological short-term memory, speech perception and speech production. The study further dissociated the response profiles of these regions and highlighted their distinct roles in speech processing.
Article
Neurosciences
Yang Zhou, Krithika Mohan, David J. Freedman
Summary: Categorization is a crucial cognitive process for decision-making and recognition, and the posterior parietal cortex, specifically the lateral intraparietal (LIP) area, is believed to transform visual feature encoding into abstract categorical representations. However, areas closer to sensory input, such as the middle temporal (MT) area, only encode stimulus features and not abstract categorical information. By studying the neuronal activity in the medial superior temporal (MST) and LIP areas during a visual motion categorization task, it has been found that MST plays a significant role in cognitive computation beyond its recognized role in visual motion processing.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Anatomy & Morphology
Sara Seoane, Cristian Modrono, Jose Luis Gonzalez-Mora, Niels Janssen
Summary: By analyzing a high spatial resolution 7T rsfMRI dataset, we found the associations between the medial temporal lobe (MTL) and different resting-state networks. Specifically, different sub-regions of the MTL were associated with different resting-state networks such as the default mode, visual, and dorsal attention networks. These findings provide new insights into the role of the MTL in resting-state networks.
BRAIN STRUCTURE & FUNCTION
(2022)
Article
Behavioral Sciences
Sebastien Ballesta, Gilles Reymond, Jean-Rene Duhamel
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2019)
Article
Anatomy & Morphology
Jerome Munuera, Jean-Rene Duhamel
BRAIN STRUCTURE & FUNCTION
(2020)
Editorial Material
Neurosciences
Article
Behavioral Sciences
Marco Neppi-Modona, Roberta Sirovich, Alessandro Cicerale, Nathalie Richard, Pascale Pradat-Diehl, Angela Sirigu, Jean-Rene Duhamel
Article
Behavioral Sciences
Sophie Gilardeau, Rossella Cirillo, Mina Jazayeri, Chloe Dupuis, Sylvia Wirth, Jean-Rene Duhamel
Summary: This study found that in spontaneous visual interactions, monkeys adjust their eye movements through mutual gaze, and amygdala neurons have different responses to the timing and type of gaze, indicating the significant role of the amygdala in eye contact.
Article
Biology
Shih-pi Ku, Eric L. Hargreaves, Sylvia Wirth, Wendy A. Suzuki
Summary: Ku et al. recorded activity in the entorhinal cortex (EC) and hippocampus (HPC) of macaques during associative learning tasks to test the computational model prediction of their role in error-driven learning. They found that the EC and HPC have prominent but differential contributions to learning from errors, with the EC playing a particularly important role in error-detection.
COMMUNICATIONS BIOLOGY
(2021)
Article
Behavioral Sciences
Julia Sliwa, Marion Mallet, Maelle Christiaens, Daniel Y. Takahashi
Summary: Primates have evolved rich communication strategies in different modalities, with specialized neural pathways coordinating their complex kin and friendship bonds. Different sensory modalities are initially processed separately but eventually share neural pathways for communication.
ETHOLOGY ECOLOGY & EVOLUTION
(2022)
Article
Multidisciplinary Sciences
Ce Mo, Irene Cristofori, Guillaume Lio, Alice Gomez, Jean-Rene Duhamel, Chen Qu, Angela Sirigu
Summary: People tend to selectively trust others based on their appearance, and regardless of facial morphology, observers unconsciously increase the contrast of the eye area to make a face appear more trustworthy. Attraction judgements, however, depend on cultural processes.
Editorial Material
Multidisciplinary Sciences
Julia Sliwa
Review
Behavioral Sciences
Sylvia Wirth, Amelie Soumier, Marina Eliava, Dori Derdikman, Shlomo Wagner, Valery Grinevich, Angela Sirigu
Summary: The text discusses the relationship between neural computations and socially meaningful territories, proposing the role of oxytocin in this process and how it may influence geometric coding to represent social territories.
TRENDS IN COGNITIVE SCIENCES
(2021)
Editorial Material
Neurosciences
Sylvia Wirth
Summary: How do differences in visual perception between rodents and primates affect the brain's construction of egocentric and allocentric reference frames for representing stimuli in space? While there are notable similarities in the egocentric spatial reference frames used by cortical regions in both rodents and primates, the representation of allocentric place appears to be more important in the primate hippocampus, which is linked to the first-person perspective of a primate's field of view. Additionally, an allocentric reference frame is suggested to be a semantic construct in primates, possibly related to conceptual framing. Finally, the use of views, based on a first-person perspective, can effectively probe episodic memory across species.
Editorial Material
Neurosciences
Edmund T. T. Rolls, Sylvia Wirth
Article
Multidisciplinary Sciences
Yidong Yang, Lei Mo, Guillaume Lio, Yulong Huang, Thomas Perret, Angela Sirigu, Jean-Rene Duhamel
Summary: Digit-tracking is a simple and calibration-free technique that can be used as an alternative to eye tracking in vision science. This system records finger movements on a touchscreen to measure eye movements and attentional focus. The results obtained using digit-tracking were comparable to those obtained using eye-tracking, supporting its validity and relevance for vision and attention research.
SCIENTIFIC REPORTS
(2023)
Review
Neurosciences
Ben Deen, Caspar M. Schwiedrzik, Julia Sliwa, Winrich A. Freiwald
Summary: Primates have developed diverse cognitive capacities to navigate their complex social world. This article examines the functional specialization in face processing, social interaction understanding, and mental state attribution to understand how the brain implements critical social cognitive abilities. The specialization occurs from single cells to neural populations to hierarchically organized networks, suggesting a pervasive theme in primate brain organization. The circuits processing social information are intertwined with systems processing nonsocial information, indicating common computations applied to different domains. The neural basis of social cognition involves distinct but interacting subnetworks in various brain regions.
ANNUAL REVIEW OF NEUROSCIENCE
(2023)