Article
Neurosciences
Joao Valente Duarte, Rodolfo Abreu, Miguel Castelo-Branco
Summary: This study investigates the functional separation between local biological motion perception and global dynamic body perception, revealing two independent processing stages and highlighting the importance of two early dorsal and two ventral visual regions in encoding biological motion.
Article
Neurosciences
Beatrice de Gelder, Elizabeth Huis In 't Veldt, Minye Zhan, Jan Van den Stock
Summary: This study investigates a new case of acquired prosopagnosia and finds that the structurally intact FFA retains face selective response despite lesions in the face perception network. At the behavioral level, impaired configural processing for facial identity was observed, but not for other stimulus categories and facial expression recognition. These findings are important for understanding the behavioral and brain basis of face perception.
Article
Neurosciences
Celia Foster, Isabelle Buelthoff, Andreas Bartels, Mintao Zhao
Summary: It has been found that human faces are processed holistically and this processing is linked to brain activity in face-responsive brain regions. Neuroimaging results suggest that neural activity in brain regions both within and outside of the face-responsive network contributes to holistic versus part-based face processing, indicating a complex network involved in facial recognition.
Article
Multidisciplinary Sciences
Zetian Yang, Winrich A. Freiwald
Summary: Faces in motion provide rich information through visual dynamics. The middle dorsal face area (MD) in the macaque monkey superior temporal sulcus (STS) shows selectivity for naturalistic face motion. Single-unit recordings from MD reveal its sensitivity to facial motion and shape, and its ability to encode complex facial motion trajectories.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Neurosciences
Maria Tsantani, Nikolaus Kriegeskorte, Katherine Storrs, Adrian Lloyd Williams, Carolyn McGettigan, Lucia Garrido
Summary: The study revealed marked differences in the information represented by the FFA and OFA, with FFA encoding higher-level perceptual and social face information, while OFA mainly driven by differences in low-level image-based properties. The results suggest that although both FFA and OFA can discriminate between identities, their representations differ in terms of encoding identity-distinguishing information.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Anatomy & Morphology
Edward H. Silson, Iris I. A. Groen, Chris I. Baker
Summary: Recent studies have shown that category-selective regions in the visual cortex exhibit systematic retinotopic biases, with stronger activation for stimuli presented in the contralateral visual field compared to the ipsilateral visual field. It remains unclear whether these responses are driven more by retinotopic location or category preference, and if there are differences in the relative strengths of these biases between different category-selective regions. The findings suggest distinct functional roles for the lateral and ventral visual cortex in processing visual information based on the spatial location of stimuli.
BRAIN STRUCTURE & FUNCTION
(2022)
Article
Neurosciences
Di Wu, Pan Zhang, Na Liu, Kewei Sun, Wei Xiao
Summary: This study investigated the effects of high-definition transcranial direct current stimulation (HD-tDCS) on face view discrimination in relation to the left FFA, left STS, and right FFA. Results indicated that individual initial performance influenced the outcomes of tDCS, highlighting the importance of considering individual differences in future research and applications.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Psychology, Clinical
Guanmin Liu, Na Zhang, Jia Yuan Teoh, Christine Egan, Thomas A. Zeffiro, Richard J. Davidson, Karina Quevedo
Summary: This study found an inverse relationship between self-compassion and neural activity during sad self-face recognition, with self-compassion correlating negatively with activity in the dorsal anterior cingulate cortex in the total sample. In depressed adolescents, higher self-compassion was associated with lower activity in the right dorsolateral prefrontal cortex during sad self-face recognition, suggesting less cognitive effort might be needed to regulate negative affect induced by sad self-faces.
PSYCHOLOGICAL MEDICINE
(2022)
Review
Chemistry, Medicinal
Yanan Feng, Wenxiu Sun, Fengcui Sun, Guoliang Yin, Pengpeng Liang, Suwen Chen, Xiangyi Liu, Tongfei Jiang, Fengxia Zhang
Summary: Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease worldwide. CD36 has been identified as a key player in the development of hepatic steatosis. Natural products acting through CD36 have shown potential in treating NAFLD.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Behavioral Sciences
Nestor Zaragoza-Jimenez, Hauke Niehaus, Ina Thome, Christoph Vogelbacher, Gabriele Ende, Inge Kamp-Becker, Dominik Endres, Andreas Jansen
Summary: This study used computational modeling and fMRI to investigate the neural mechanisms of face identity learning and familiar face recognition, and found that specific face-sensitive brain regions are associated with these processes. The results further support the central principles of predictive coding theory, but there are diverging findings regarding the specific computational model parameters reflected in brain activity.
Article
Behavioral Sciences
Dorita H. F. Chang, Nikolaus F. Troje, Yuji Ikegaya, Ichiro Fujita, Hiroshi Ban
Summary: The study aimed to understand the spatiotemporal characteristics of biological motion perception. Univariate response components were observed at around 200ms and 650ms post-stimulus onset, with multivariate patterns specific to form discriminated as early as 100ms. Early responses to biological motion likely originate from occipital cortex, while later responses likely come from extrastriate body areas.
Article
Behavioral Sciences
Vadim Axelrod, Camille Rozier, Tal Seidel Malkinson, Katia Lehongre, Claude Adam, Virginie Lambrecq, Vincent Navarro, Lionel Naccache
Summary: This study reports a rare case in which multi-unit activity was recorded near the fusiform face area (FFA), and explores the interactions between facial expression processing and other stages of facial processing. The results suggest that face-selective units and modulation by facial expression stimuli likely reflect feed-forward processing.
Article
Multidisciplinary Sciences
Zetian Yang, Winrich A. Freiwald
Summary: Research in macaque monkeys has shown the existence of a network in the temporal lobe supporting face processing, including the middle dorsal (MD) face area. This area encodes facial identity, head orientation, expression, and gaze, forming a multidimensional code. MD not only encodes structural properties but also changeable ones, making it capable of providing information about another animal's direction of attention.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Ruidi Wang, Xiqian Lu, Yi Jiang
Summary: Using functional magnetic resonance imaging, researchers identified brain areas related to facing direction, gender, and emotional state encoded in biological motion. These attributes were found to be encoded in a hierarchical structure, with modulation between each other. Additionally, some brain areas specific to attribute encoding were found to be correlated with behavioral results.
Article
Neurosciences
David D. Coggan, David M. Watson, Ao Wang, Robert Brownbridge, Christopher Ellis, Kathryn Jones, Charlotte Kilroy, Timothy J. Andrews
Summary: This study aimed to investigate the selectivity of the fusiform face area (FFA) and parahippocampal place area (PPA) to images of faces and places based on their shape or texture properties. The findings suggest that the neural selectivity in FFA and PPA is sensitive to variation in the shape properties of the image at a coarse spatial scale, but to the texture properties of the image at a finer scale.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Psychiatry
Ayline Maier, Caroline Gieling, Luca Heinen-Ludwig, Vlad Stefan, Johannes Schultz, Onur Guentuerkuen, Benjamin Becker, Rene Hurlemann, Dirk Scheele
AMERICAN JOURNAL OF PSYCHIATRY
(2020)
Article
Neurosciences
Ksander N. de Winkel, Florian Soyka, Heinrich H. Buelthoff
EXPERIMENTAL BRAIN RESEARCH
(2020)
Article
Multidisciplinary Sciences
Ann-Kathrin Kreuder, Dirk Scheele, Johannes Schultz, Juergen Hennig, Nina Marsh, Torge Dellert, Ulrich Ettinger, Alexandra Philipsen, Mari Babasiz, Angela Herscheid, Laura Remmersmann, Ruediger Stirnberg, Tony Stoeckerh, Rene Hurlemann
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2020)
Article
Ophthalmology
Karin S. Pilz, Juho M. Aijala, Mauro Manassi
Article
Neurosciences
Tugrul Irmak, Ksander N. de Winkel, Daan M. Pool, Heinrich H. Bulthoff, Riender Happee
Summary: The study found a relationship between individual motion perception characteristics and motion sickness sensitivity, with considerable variability in frequency sensitivities among individuals. While no significant group-level effect of frequency on motion sickness was observed, a strong positive correlation was found between the subjective vertical time constant and general motion sickness sensitivity at the individual level.
EXPERIMENTAL BRAIN RESEARCH
(2021)
Article
Clinical Neurology
Marie Coenjaerts, Frederike Pape, Virginia Santoso, Franziska Grau, Birgit Stoffel-Wagner, Alexandra Philipsen, Johannes Schultz, Rene Hurlemann, Dirk Scheele
Summary: The study found that women are more sensitive to fairness frames compared to men, and estradiol has sex-specific effects on fairness sensitivity. Moreover, the mere belief of receiving estradiol treatment significantly increased the acceptance of unfair-framed offers in both sexes.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2021)
Article
Behavioral Sciences
Mirko Lehmann, Claudia Neumann, Sven Wasserthal, Achilles Delis, Johannes Schultz, Rene Hurlemann, Ulrich Ettinger
Summary: This study investigated the effects of ketamine on metacognition and found that ketamine induced deterioration in metacognitive performance. Exploratory analysis also revealed changes in functional connectivity during metacognitive confidence ratings, possibly indicating re-representations of object-level features supplied for metacognitive evaluations.
BEHAVIOURAL BRAIN RESEARCH
(2022)
Article
Geriatrics & Gerontology
Simona Garobbio, Karin S. Pilz, Marina Kunchulia, Michael H. Herzog
Summary: Recent research has shown a connection between cognitive and visual impairments, with two main theories being sensory deprivation and common cause. This study aimed to reconcile these theories and test the link between visual and cognitive decline in individuals with mild cognitive impairment. The results indicate a strong association between visual impairment and mild cognitive impairment, with only weak correlations between most tests for older adults with mild cognitive impairment.
EXPERIMENTAL AGING RESEARCH
(2023)
Meeting Abstract
Ophthalmology
Fiammetta Marini, Karin S. Pilz, Mauro Manassi
Article
Psychology, Experimental
Ian M. Thornton, Quoc C. Vuong, Karin S. Pilz
Summary: Evidence suggests a visual processing advantage for horizontal over vertical orientations in top-down visual search, with participants being faster, more efficient, and more accurate when searching for horizontal targets. This indicates strong orientation anisotropies in attentional templates guiding search for known targets.
Article
Psychology, Biological
Mirko Lehmann, Claudia Neumann, Sven Wasserthal, Johannes Schultz, Achilles Delis, Peter Trautner, Rene Hurlemann, Ulrich Ettinger
Summary: The study found that ketamine administration had detrimental effects on metacognition, resulting in larger metacognitive bias and deterioration of metacognitive sensitivity. Additionally, ketamine elicited increased activation in certain areas of the brain, although this activation was not specific to metacognitive confidence ratings.
NEUROSCIENCE OF CONSCIOUSNESS
(2021)
Article
Psychology, Multidisciplinary
Qendresa Rramani, Holger Gerhardt, Xenia Grote, Weihua Zhao, Johannes Schultz, Bernd Weber
FRONTIERS IN PSYCHOLOGY
(2020)
Article
Psychology, Experimental
Hannah C. Agnew, Louise H. Phillips, Karin S. Pilz
PSYCHOLOGICAL RESEARCH-PSYCHOLOGISCHE FORSCHUNG
(2020)
Meeting Abstract
Neurosciences
Ann-Kathrin Kreuder, Dirk Scheele, Johannes Schultz, Juergen Hennig, Nina Marsh, Torge Dellert, Ulrich Ettinger, Alexandra Philipsen, Mari Babasiz, Angela Herscheid, Laura Remmers-mann, Ruediger Stirnberg, Tony Stoecker, Rene Hurlemann
NEUROPSYCHOPHARMACOLOGY
(2019)
Meeting Abstract
Ophthalmology
Karin S. Pilz