Article
Neurosciences
Ana Arsenovic, Anja Ischebeck, Natalia Zaretskaya
Summary: This study found that different regions of the human visual system respond to illusory shapes, with the intraparietal sulcus areas showing a preference towards contralateral shapes. Additionally, as task difficulty increased, anterior areas displayed response attenuation. The research suggests that the intraparietal sulcus can represent illusory content generated not only by moving stimuli, but also by stationary stimuli.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Eric Mooshagian, Eric A. Yttri, Arthur D. Loewy, Lawrence H. Snyder
Summary: The canonical view of motor control states that distal muscles are primarily controlled by the contralateral cerebral hemisphere. However, recent studies have shown that the parietal reach region in the contralateral hemisphere plays a significant role in reach preparation.
JOURNAL OF NEUROSCIENCE
(2022)
Review
Neurosciences
Celia Foster, Wei-An Sheng, Tobias Heed, Suliann Ben Hamed
Summary: The paper reviews the important role of macaque VIP in sensorimotor and cognitive functions and integrates human studies, revealing three homologous structures of human VIP that are different in functionality from macaque VIP.
PROGRESS IN NEUROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Bin Zhao, Rong Wang, Zhihua Zhu, Qianli Yang, Aihua Chen
Summary: The macaque Visual Posterior Sylvian (VPS) area contains neurons that selectively respond to heading direction in both visual and vestibular modalities. However, it is unclear how these neurons combine the two sensory signals. Unlike the medial superior temporal area (MSTd), which shows subadditive characteristics, VPS responses are dominated by vestibular signals. Information analysis reveals that VPS encodes information from distinct sensory modalities, similar to MSTd, but with more emphasis on vestibular signals. Single neuron responses in both areas can be well explained by a weighted linear sum of unimodal responses. Additionally, normalization models capture the interaction characteristics between vestibular and visual signals in both VPS and MSTd, indicating the presence of divisive normalization mechanism in the cortex.
Article
Multidisciplinary Sciences
Joshua A. Seideman, Terrence R. Stanford, Emilio Salinas
Summary: The study shows that spatial selection in LIP is distinct from, and may even conflict with, evidence accumulation during saccadic choices. This finding is important for understanding the guidance mechanisms of eye movements.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Youngsun T. Cho, Flora Moujaes, Charles H. Schleifer, Martina Starc, Jie Lisa Ji, Nicole Santamauro, Brendan Adkinson, Antonija Kolobaric, Morgan Flynn, John H. Krystal, John D. Murray, Grega Repovs, Alan Anticevic
Summary: This study investigated how reward and loss impact spatial working memory precision and neural circuits in human subjects. The results showed that both reward and loss improved spatial working memory precision, with specific regions like precentral sulcus and intraparietal sulcus having increased BOLD signal related to better working memory precision. Conversely, areas straddling executive networks displayed decreased BOLD signal during incentivized working memory.
Article
Biology
Rikako Kato, Takuya Hayashi, Kayo Onoe, Masatoshi Yoshida, Hideo Tsukada, Hirotaka Onoe, Tadashi Isa, Takuro Ikeda
Summary: Research using PET imaging reveals altered brain activity in blindsight macaques that lack visual awareness but can still perform visual motor tasks, showing significant changes in activity of the lateral bank of the intraparietal sulcus (lbIPS) bilaterally. Injection of muscimol into this region impairs visuomotor performance, suggesting a role for bilateral lbIPS in visuomotor function in blindsight conditions.
COMMUNICATIONS BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
S. Shushruth, Ariel Zylberberg, Michael N. Shadlen
Summary: The study of perceptual decision-making in monkeys has provided insights into how sensory evidence is integrated for decision-making. When monkeys are aware of the motor actions related to their decisions, the integration of evidence is carried out by neurons involved in the selection of these actions. However, it is unclear how monkeys make decisions when they are unaware of the required actions, which is referred to as abstract decisions. This study trained monkeys to associate the direction of motion with the color of two targets and found that monkeys postponed decision formation until the targets were revealed. Neurons in the parietal association area represented the integration of evidence leading to a choice, but the samples of evidence must have been retrieved from short-term memory since the stimulus was no longer visible.
Article
Cell Biology
Kentaro Miyamoto, Rieko Setsuie, Yasushi Miyashita
Summary: This study explores how monkeys integrate confidence read-outs from different sources of concepts when wagering based on mnemonic decision performance. The research suggests the existence of a time-consuming compensatory metacognitive process, with the posterior inferior parietal lobe potentially playing a role in metacognitive concept integration.
Article
Neurosciences
Sara R. J. Gilissen, Karl Farrow, Vincent Bonin, Lutgarde Arckens
Summary: The posterior parietal cortex (PPC) in mice is proposed to be comprised of at least six subregions, including RL, AM, and MMA. These subregions exhibit different connectivity patterns and receive inputs from different cortical areas, suggesting distinct functions for each. These anatomical findings pave the way for a deeper understanding of how the PPC and its subdivisions contribute to multisensory integration-based behavior in mice.
Article
Neurosciences
Michela Gamberini, Lauretta Passarelli, Daniele Impieri, Giulia Montanari, Stefano Diomedi, Katrina H. Worthy, Kathleen J. Burman, David H. Reser, Patrizia Fattori, Claudio Galletti, Sophia Bakola, Marcello G. P. Rosa
Summary: The study found that posterior parietal areas receive more extensive projections from the claustrum than previously thought, including afferents from the anterior and ventral regions. The exact regions of claustrum origin of projections vary according to target areas.
Article
Neurosciences
Yang Zhou, Ou Zhu, David J. Freedman
Summary: In this study, reversible pharmacological inactivation of LIP neural activity was used to investigate its role in visual categorical decisions. The results showed that LIP plays a generalized role in these decisions, independent of task structure and motor response modality.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Kaushik J. Lakshminarasimhan, Eric Avila, Xaq Pitkow, Dora E. Angelaki
Summary: Success in real-world tasks depends on the ability to track hidden states, which neural populations do by processing sensory history and recurrent interactions reflecting the internal model of the world.
NATURE COMMUNICATIONS
(2023)
Article
Psychology, Multidisciplinary
Hyun Jung Han, Sangil Lee, Wi Hoon Jung
Summary: Motivation plays a critical role in human cognitive function. This study classified individuals' behavioral responses and discovered two distinct groups with different achievement motivation orientations. Structural brain analysis and functional magnetic resonance imaging data revealed neural mechanisms related to achievement motivation.
CURRENT PSYCHOLOGY
(2022)
Article
Neurosciences
Hirotake Yokota, Naofumi Otsuru, Kei Saito, Sho Kojima, Shota Miyaguchi, Yasuto Inukai, Kazuaki Nagasaka, Hideaki Onishi
Summary: Changes in alpha-band cortical oscillatory activity affect perception, with alpha-tACS applied over the left PPC reducing TPD threshold significantly compared to that applied over the left S1. This study provides empirical evidence that alpha-tACS exerts region-specific effects on determining TPD threshold assessed in the contralateral index finger pad.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Neurosciences
Adele M. H. Seelke, Allison M. Perkeybile, Rebecca Grunewald, Karen L. Bales, Leah A. Krubitzer
JOURNAL OF COMPARATIVE NEUROLOGY
(2016)
Article
Anatomy & Morphology
James C. Dooley, Joao G. Franca, Adele M. H. Seelke, Dylan F. Cooke, Leah A. Krubitzer
FRONTIERS IN NEUROANATOMY
(2015)
Article
Neurosciences
Auriane Duchemin, Adele M. H. Seelke, Trenton C. Simmons, Sara M. Freeman, Karen L. Bales
Article
Neurosciences
Adele M. H. Seelke, James C. Dooley, Leah A. Krubitzer
JOURNAL OF COMPARATIVE NEUROLOGY
(2013)
Article
Neurosciences
James C. Dooley, Joao G. Franca, Adele M. H. Seelke, Dylan F. Cooke, Leah A. Krubitzer
JOURNAL OF COMPARATIVE NEUROLOGY
(2013)
Article
Neurosciences
Adele M. H. Seelke, James C. Dooley, Leah A. Krubitzer
JOURNAL OF COMPARATIVE NEUROLOGY
(2014)
Article
Neurosciences
J. C. Dooley, H. M. Nguyen, A. M. H. Seelke, L. Krubitzer
Article
Neurosciences
A. M. H. Seelke, J. C. Dooley, L. A. Krubitzer
Article
Multidisciplinary Sciences
Adele M. H. Seelke, James C. Dooley, Leah A. Krubitzer
Article
Multidisciplinary Sciences
Leah A. Krubitzer, Adele M. H. Seelke
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2012)
Letter
Neurosciences
Danielle Beckman, Adele Seelke, John H. Morrison, Eliza Bliss-Moreau
JOURNAL OF NEUROSCIENCE RESEARCH
(2020)
Article
Biology
Danielle Beckman, Adele M. H. Seelke, Jeffrey Bennett, Paige Dougherty, Koen K. A. Van Rompay, Rebekah Keesler, Patricia A. Pesavento, Lark L. A. Coffey, John H. Morrison, Eliza Bliss-Moreau
Summary: In this study, we evaluated the neuropathological consequences of fetal exposure to ZIKV in rhesus monkeys, and found that the virus can cause structural abnormalities and cell death in the developing brain. These findings may help explain why some infants born with normal sized heads during ZIKV infection experience developmental challenges as they age.
Article
Endocrinology & Metabolism
Alexander Baxter, Chloe L. Karaskiewicz, Lindsey A. Campbell, Erin L. Kinnally, Emilio Ferrer, Adele H. M. Seelke, Sara M. Freeman, Karen L. Bales
Summary: This study examined the changes in vasopressin receptors and androgens in male and female parents of titi monkeys, a pair-bonding and biparental species. The results showed that parents had lower vasopressin receptor binding in most brain regions and a negative correlation between parental experience and androgen levels, suggesting that these hormones are associated with parenting behavior and physiology in titi monkeys.
JOURNAL OF NEUROENDOCRINOLOGY
(2023)
Article
Genetics & Heredity
Adele M. H. Seelke, Jessica M. Bond, Trent C. Simmons, Nikhil Joshi, Matthew L. Settles, Danielle Stolzenberg, Mijke Rhemtulla, Karen L. Bales
ENVIRONMENTAL EPIGENETICS
(2018)