Review
Neurosciences
Xiaoyi Li, Kai Zhang, Xiao He, Jinyun Zhou, Chentao Jin, Lesang Shen, Yuanxue Gao, Mei Tian, Hong Zhang
Summary: Recent neuroimaging studies have provided insights into the neurobiological processes associated with ASD, with MRI revealing abnormal developmental trajectories, functional MRI highlighting disrupted neural networks, and PET/SPECT imaging indicating metabolic and neurotransmitter abnormalities contributing to aberrant neural circuits in ASD.
NEUROSCIENCE BULLETIN
(2021)
Article
Neurosciences
Yajuan Wang, Yingshuang Wang, Lihong Bu, Shaoyang Wang, Xinhui Xie, Fuchun Lin, Zheman Xiao
Summary: This study examines the differences in resting-state functional connectivity (rsFC) between migraine and tension-type headache patients, focusing on brain regions associated with cognition and emotion. The results demonstrate that rsFC alterations in the amygdala and hippocampus with the occipital lobe can be effective in distinguishing patients with migraine from patients with tension-type headaches.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Neurosciences
Hongzan Sun, Yong He, Heqi Cao
Summary: NSFC has been funding various research programs related to fMRI over the past two decades, with increasing support particularly in the General Program and Key Program. Leading research institutes in economically developed provinces and municipalities received the most support and established close collaboration relationships. Notable achievements in data analysis methods, brain connectomes, and computational platforms as well as their applications in brain disorders were reviewed.
CNS NEUROSCIENCE & THERAPEUTICS
(2021)
Article
Neurosciences
Christopher J. Hyatt, Bruce E. Wexler, Brian Pittman, Alycia Nicholson, Godfrey D. Pearlson, Silvia Corbera, Morris D. Bell, Kevin Pelphrey, Vince D. Calhoun, Michal Assaf
Summary: Autism spectrum disorder (ASD), schizophrenia (SZ), and typically developed (TD) individuals were compared in their engagement in dynamic functional network connectivity (dFNC) states during social-emotional processing. Results showed differences in neural processing of emotions between ASD and TD, with ASD spending more time in a sad-associated state compared to TD individuals. This highlights the importance of examining whole-brain reconfiguration of FNC to understand unique emotion-specific dFNC states.
Review
Biophysics
Pedro Henrique Rodrigues da Silva, Andre Monteiro Paschoal, Kaio Felippe Secchinatto, Maria Clara Zanon Zotin, Antonio Carlos dos Santos, Anand Viswanathan, Octavio M. Pontes-Neto, Renata Ferranti Leoni
Summary: The application of contrast agent-free, state-of-the-art MRI techniques, particularly DTI and fMRI, provide a complete understanding of brain damage and structural and functional connectivity impairment related to cSVD. These techniques contribute to identifying cSVD markers and exploring unanswered questions.
NMR IN BIOMEDICINE
(2022)
Article
Neurosciences
Ke Song, Yong Wang, Mei-Xia Ren, Jiao Li, Ting Su, Si-Yi Chen, Yi Shao, Ya-Li Lv
Summary: Using resting-state functional connectivity, this study found abnormal neural activities in specific brain regions of patients with optic neuritis, with significant changes in rsFC, longFCD, and IFCD values, which may help identify the specific mechanism of change in brain function in ON.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Medicine, General & Internal
Yang Liu, Hui-Qun Fu, Yan Wu, Zun-Shu Du, Bo-Ran Li, Xin Gao, Guan-Wen Lin, Shu-Yi Yang, Tian-Long Wang
Summary: Resting-state functional magnetic resonance imaging (rs-fMRI) is a promising method for studying brain function, typically performed on anesthetized animals. This study found that different anesthesia methods in aged rats can lead to variations in functional connectivity in different brain regions. Isoflurane anesthesia may be a suitable substitute for Isoflurane + Dexmedetomidine anesthesia in default mode network studies, depending on the regions of interest.
CHINESE MEDICAL JOURNAL
(2021)
Article
Neurosciences
Jianing Hao, Xintao Hu, Liting Wang, Lei Guo, Junwei Han
Summary: The study suggests that the human cerebellum is involved in a wide range of cognitive tasks beyond traditional motor control and can be divided into distinct functional subregions. By utilizing a naturalistic paradigm of fMRI, the research successfully identified different subregions of the cerebellum, providing an alternative template for exploring neural activities in naturalistic environments.
FRONTIERS IN NEUROSCIENCE
(2021)
Review
Clinical Neurology
Nathan T. Cohen, Hua Xie, Taha Gholipour, William D. Gaillard
Summary: This article summarizes the evidence to date on the network basis of FCD-related epilepsy, and highlights the potential applications of rsfMRI in the diagnosis and treatment of FCD-related epilepsy. Numerous studies have shown a global disruption of cortical functional networks in FCD-related epilepsy, and the underlying pathological subtypes of FCD influence overall functional network patterns.
Article
Engineering, Biomedical
Gang Qu, Wenxing Hu, Li Xiao, Junqi Wang, Yuntong Bai, Beenish Patel, Kun Zhang, Yu-Ping Wang
Summary: In this study, a graph convolutional network (GCN) based framework is proposed for brain functional connectivity analysis. The experimental results show that the proposed framework outperforms other competing models in classifying different achievement levels and can identify cognition-related brain functional networks.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2022)
Article
Neurosciences
Elvisha Dhamala, Keith W. Jamison, Abhishek Jaywant, Sarah Dennis, Amy Kuceyeski
Summary: White matter pathways play a crucial role in facilitating neuronal coactivation patterns in the brain. This study integrates neuroimaging, connectomics, and machine learning methods to explore the relationship between functional and structural brain connectivity with cognition. The results suggest that functional connectivity is more predictive of cognitive scores than structural connectivity, and that distinct functional and structural connections are associated with crystallised and fluid cognitive abilities.
HUMAN BRAIN MAPPING
(2021)
Article
Neurosciences
Jing Jin, Xiu-Qin Wang, Xue Yang, Na Zhao, Zi-Jian Feng, Yu-Feng Zang, Li-Xia Yuan
Summary: Functional connectivity (FC) derived from resting-state functional magnetic resonance imaging has been used to guide repetitive transcranial magnetic stimulation (rTMS) for autism spectrum disorder (ASD). In this study, the authors aimed to develop an individualized localization method for rTMS treatment of male ASD. They found stronger peak FC in the right dorsolateral prefrontal cortex (DLPFC) in ASD compared to typically-developed controls. Additionally, a negative correlation was found between peak FC strength in the right DLPFC and symptoms of ASD.
HUMAN BRAIN MAPPING
(2023)
Article
Clinical Neurology
N. Tuovinen, A. Stefani, T. Mitterling, A. Heidbreder, B. Frauscher, E. R. Gizewski, W. Poewe, B. Hoegl, C. Scherfler
Summary: Patients with restless legs syndrome showed alterations in connectivity within different resting-state networks, with some networks showing increased connectivity and others showing decreased connectivity, corresponding to regions associated with attention, response inhibitory control, and processing of sensory information. Patients on dopaminergic medication displayed increased connectivity between the thalamus and prefrontal regions.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Neurosciences
Xin Zhang, Jiayue Liu, Yang Yang, Shijie Zhao, Lei Guo, Junwei Han, Xintao Hu
Summary: The study examined the test-retest reliability of dynamic functional connectivity (dFC) in functional magnetic resonance imaging (fMRI) under natural viewing condition, revealing significantly improved reliability compared to resting state. This suggests that naturalistic paradigms may enhance the study of functional brain networks using fMRI.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Tao Yin, Zhaoxuan He, Yuan Chen, Ruirui Sun, Shuai Yin, Jin Lu, Yue Yang, Xiaoyan Liu, Peihong Ma, Yuzhu Qu, Tingting Zhang, Xueling Suo, Du Lei, Qiyong Gong, Yong Tang, Fanrong Liang, Fang Zeng
Summary: This study successfully predicted the responsiveness of functional dyspepsia (FD) patients to acupuncture treatment by using functional brain network features and constructing support vector machine models. The results showed a certain level of accuracy in predicting patient responsiveness and symptom relief. Thirty-eight functional brain network features associated with the orbitofrontal cortex, caudate, hippocampus, and anterior insula were identified as critical predictive features. Changes in these features were more pronounced in responders than in non-responders. This research provides a promising approach for predicting individual acupuncture efficacy.
Article
Psychology
Jing Wang, Vladimir L. Cherkassky, Ying Yang, Kai-min Kevin Chang, Robert Vargas, Nicholas Diana, Marcel Adam Just
COGNITIVE NEUROPSYCHOLOGY
(2016)
Article
Neurosciences
Saudamini Roy Damarla, Vladimir L. Cherkassky, Marcel Adam Just
HUMAN BRAIN MAPPING
(2016)
Article
Neurosciences
Jing Wang, Vladimir L. Cherkassky, Marcel Adam Just
HUMAN BRAIN MAPPING
(2017)
Article
Health Policy & Services
Jessica E. Gormley, Diane L. Williams
JOURNAL OF PEDIATRIC HEALTH CARE
(2019)
Article
Audiology & Speech-Language Pathology
Kelly L. Coburn, Diane L. Williams
AMERICAN JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
(2020)
Article
Behavioral Sciences
Laura E. Quinones-Camacho, Frank A. Fishburn, Katherine Belardi, Diane L. Williams, Theodore J. Huppert, Susan B. Perlman
Summary: The study found that individuals with ASD had less neural synchrony in the TPJ region during social interactions, leading to more severe social communication impairments, although they did not have fewer utterances compared to controls.
Editorial Material
Psychology, Biological
Marcel Adam Just, Vladimir L. Cherkassky, David Brent
NATURE HUMAN BEHAVIOUR
(2021)
Article
Psychology, Developmental
Kelly L. Coburn, Diane L. Williams
Summary: Challenges with verbal encoding may hinder autistic individuals' ability to express their ideas, making visuospatial expression a potentially more accurate representation of their knowledge and skills. The level of intention of different stimulus categories does not consistently impact response accuracy in these individuals. Participants who use visuospatial responses before verbal responses and those who have seen more stimuli tend to attribute higher intentionality to shapes in animations designed to trigger mentalizing processes. Modalities of expression may impact the accuracy of responses by autistic individuals.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Article
Neurosciences
Robert Vargas, Marcel Adam Just
Summary: Recent research suggests that there is a common neural organization for representing abstract concepts among English and Mandarin speakers. By using multivariate pattern analytic techniques on fMRI data, researchers found four underlying neurosemantic dimensions that were sufficient for reliably identifying individual abstract concepts across languages. While some individual concepts may have different meanings, these differences can be explained in terms of the salience of specific dimensions.
HUMAN BRAIN MAPPING
(2022)
Retraction
Psychology, Biological
Marcel Adam Just, Lisa Pan, Vladimir L. Cherkassky, Dana L. McMakin, Christine Cha, Matthew K. Nock, David Brent
NATURE HUMAN BEHAVIOUR
(2023)
Correction
Education & Educational Research
Robert A. Mason, Reinhard A. Schumacher, Marcel Adam Just
NPJ SCIENCE OF LEARNING
(2021)
Article
Education & Educational Research
Robert A. Mason, Reinhard A. Schumacher, Marcel Adam Just
Summary: Using cognitive neuroscience methods, this study investigated the neural representation and cognitive dimensions of physics concepts in the brains of 10 physics faculty members. The findings suggest that the human brain systematically organizes novel scientific concepts in terms of new dimensions of neural representation.
NPJ SCIENCE OF LEARNING
(2021)
Article
Psychology, Biological
Marcel Adam Just, Lisa Pan, Vladimir L. Cherkassky, Dana L. McMakin, Christine Cha, Matthew K. Nock, David Brent
NATURE HUMAN BEHAVIOUR
(2017)
Article
Behavioral Sciences
Diane L. Williams, Nancy J. Minshew, Gerald Goldstein, Carla A. Mazefsky
Article
Psychology, Multidisciplinary
Robert A. Mason, Marcel Adam Just
PSYCHOLOGICAL SCIENCE
(2016)