Article
Materials Science, Ceramics
Omayra Beatriz Ferreiro Balbuena, Lilian Fernanda Santos Paiva, Alexandre Antunes Ribeiro, Magna Maria Monteiro, Marize Varella de Oliveira, Luiz Carlos Pereira
Summary: This study focused on investigating the sintering parameters of biphasic calcium phosphate bioceramics to find better conditions for avoiding defect generation. The results showed that suitable sintering parameters promoted particle consolidation and the transformation from hydroxyapatite to beta-tricalcium phosphate occurred simultaneously with grain growth and material densification under all conditions.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Ceramics
Teliang Lu, Yali Miao, Xinyuan Yuan, Yu Zhang, Jiandong Ye
Summary: In this study, the effects of Mg doping on the physicochemical and biological properties of BCP scaffold were systematically studied. The results showed that Mg doping improved the sintering of BCP scaffold and reduced the degradation rate at the initial soaking period, but damaged the lattice stability of BCP and increased the degradation rate at the later soaking period. BCP scaffolds with Mg doping content ≥3 mol.% could achieve long-term sustained release of Mg and promote osteogenic differentiation and angiogenic activity.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Multidisciplinary
T. Lu, X. Yuan, L. Zhang, F. He, X. Wang, J. Ye
Summary: In this study, zinc doping was introduced into BCP scaffolds to regulate the balance between pro-osteogenesis and anti-osteoclastogenesis, thereby improving bone repair effect. The results showed that zinc doping could modulate the differentiation of osteoblasts and osteoclasts, and enhance osteoinduction activity and accelerate new bone formation. This study is of great significance for the development of more osteoinductive calcium phosphate-based materials for bone regeneration.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Kyung-Hyeon Yoo, Yeon Kim, Yong-Il Kim, Moon-Kyoung Bae, Seog-Young Yoon
Summary: This study found that an appropriate amount of lithium ion doping (approximately 10%) can improve the biological properties of biphasic calcium phosphate and facilitate medical applications. However, high concentrations of lithium ions exceeding 10% can lead to crystal instability, which is not conducive to the osteogenic behavior of human dental pulp stem cells.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Physical
Siqi Cheng, Wenna Li, Shunhua Xiao, Shuai Zheng, Zhuo Chen, Lizhen Hu, Qing Zhu, Bin Huang, Qingquan Liu, Quanqi Chen
Summary: The calcination temperature significantly affects the physical and electrochemical performance of Na4MnV(PO4)(3)/C composites. The surface area, carbon disorder, Na+ diffusion coefficients, and electrochemical performance are greatly influenced by the calcination temperature. Additionally, the optimal calcination temperature for the composites is found to be 750 degrees C, resulting in the highest capacity, best rate capability, and cyclability.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Materials Science, Multidisciplinary
Teliang Lu, Xinyuan Yuan, Luhui Zhang, Fupo He, Xiaolan Wang, Yu Zhang, Jiandong Ye
Summary: By introducing a high throughput experimental/screening method into elements-doped calcium phosphate, this study successfully synthesized zinc-doped BCP with gradient doping content and investigated the effects of doping content on its properties. The results showed that proper zinc doping could promote osteogenic differentiation of bone marrow mesenchymal stem cells, but high doping content may lead to cell apoptosis.
APPLIED MATERIALS TODAY
(2021)
Article
Chemistry, Physical
Pooja Bhaskar Madambikkattil, Shantikumar V. Nair, Dhamodaran Santhanagopalan
Summary: In this study, the electrochemical performance of Na3V2(PO4)(3) cathode material was improved through dual-doping with Cr and Mg. The optimal doping concentration of 0.1 for both Cr and Mg showed positive effects on the capacity, rate performance, and cycling stability of the cathode material.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Materials Science, Ceramics
Yuyi Wang, Menglu Wang, Fuying Chen, Cong Feng, Xuening Chen, Xiangfeng Li, Yumei Xiao, Xingdong Zhang
Summary: This study found that the addition of calcium oxide (CaO) can stabilize the CDHA phase in BCP ceramics, improve their mechanical and biological properties, and better mimic the composition and structure of natural bone minerals.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2021)
Article
Materials Science, Multidisciplinary
Salih Alper Akalin, Mustafa Erol, Begum Uzunbayir, Sibel Oguzlar, Serdar Yildirim
Summary: NiOx, Li:NiOx, and Li,Mg:NiOx powders were produced by sol-gel method, and their structural and optical properties were studied. XPS results confirmed the successful incorporation of Li+ and Mg2+ into NiOx structure, with decreased crystallite size as dopant concentration increased. Addition of Li+ and Mg2+ led to reduced emission intensity and average decay time compared to pristine NiOx.
Article
Chemistry, Physical
Marta Kalbarczyk, Aleksandra Szczes, Anna Belcarz, Paulina Kazimierczak, Zoltan May
Summary: Using hen eggshells as a calcium source, calcium phosphate materials were synthesized through a simple and environmentally friendly wet synthesis method. The incorporation of Zn ions into hydroxyapatite (HA) was successfully demonstrated. The composition of the obtained ceramics depended on the zinc content, with the presence of dicalcium phosphate dihydrate (DCPD) increasing as the concentration of Zn increased. All doped HA materials exhibited antimicrobial activity against S. aureus and E. coli. However, these materials showed cytotoxic effects on preosteoblasts (MC3T3-E1 Subclone 4) in vitro, most likely due to their high ionic reactivity.
Article
Chemistry, Multidisciplinary
Thomas Dippong, Erika Andrea Levei, Iosif Grigore Deac, Ioan Petean, Gheorghe Borodi, Oana Cadar
Summary: Investigation was conducted on the structure, morphology, and magnetic properties of (Ni0.6Mn0.4Fe2O4)(alpha)(SiO2)(100-alpha) nanocomposites produced by sol-gel synthesis. The findings revealed that the crystallite size, saturation magnetization, remanent magnetization, and coercive field increased with higher calcination temperature and ferrite content. The SiO2 matrix displayed a diamagnetic behavior with a minor ferromagnetic fraction, while the Ni0.6Mn0.4Fe2O4 embedded in SiO2 matrix exhibited superparamagnetic behavior, and unembedded Ni0.6Mn0.4Fe2O4 showed high-quality ferromagnetic behavior.
Article
Materials Science, Multidisciplinary
D. M. Druzian, G. Pavoski, D. C. R. Espinosa, A. K. Machado, W. L. Da Silva
Summary: The study focuses on developing and characterizing nanobioglass from rice husk residues to enhance osteoconductivity for bone tissue applications. The experimental results show that nanobioglass containing magnesium exhibits excellent cellular safety, biocompatibility, and bioactivity, making it a promising biomaterial for bone regeneration.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Materials Science, Multidisciplinary
Naruporn Monmaturapoj, Theerawat Uanlee, Katanchalee Nampuksa, Anchittha Kasiwat, Chalumkwan Makornpan
Summary: Porous biphasic calcium phosphate scaffolds containing bioactive glass have been prepared, showing improved antibacterial activity, in vitro bioactivity, and mechanical properties. Different amounts of bioactive glass affect the density, shrinkage, and compressive strength of the scaffolds.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Engineering, Environmental
Jordi Sans, Marc Arnau, Vanesa Sanz, Pau Turon, Carlos Aleman
Summary: This study investigates the interaction between hydroxyapatite and brushite at high temperatures, finding that the catalyst composed of these two materials can produce formic acid or acetic acid depending on the ratio. The results demonstrate the plasticity of this catalyst system and its potential as a green alternative for CO2 fixation.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Physical
Tithi Sen, Amrita Biswas, Tapan Kumar Rout, Rajalingam Thangavel, Udayabhanu Gopalakrishnan Nair
Summary: Heavily Zinc ion-doped nickel oxide thin films were prepared and studied for their structural, optical, and electrical properties. The increase in dopant concentration was found to affect the absorbance spectra and surface roughness of the films.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Materials Science, Multidisciplinary
M. K. Ramezani, S. Ramesh, J. Purbolaksono, R. Das
Summary: This study numerically investigates stress intensity factors (SIFs) for semi-elliptical surface cracks with different inclination angles in a cylindrical bar under pure tension. By using a dual-boundary element method and proposing general closed-form solutions, accurate and reliable values of SIFs can be obtained rapidly compared to computational models. These results can be utilized as inputs for failure studies and life evaluations of cracked cylinders in working conditions.
ACTA MECHANICA SOLIDA SINICA
(2022)
Editorial Material
Materials Science, Composites
Corrado Piconi, Simone Sprio
JOURNAL OF COMPOSITES SCIENCE
(2022)
Article
Materials Science, Ceramics
Constance Linda Gnanasagaran, Karthikeyan Ramachandran, S. Ramesh, Sutharsini Ubenthiran, Nashrah Hani Jamadon
Summary: The effect of co-doping of titania and manganese oxide at different weight percentages on sintering behaviour and mechanical properties of alumina were studied. The addition of doping reduced the sintering temperature and improved the density and mechanical properties of alumina. XRD analysis revealed the formation of R-TiO2 and alpha-alumina at low sintering temperature, which further reacted to form Al2TiO5 at higher sintering temperature. MnO2 did not react with alumina due to atomic radii mismatch. SEM showed abnormal grain growth with increasing sintering temperature and dopant composition.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Ceramics
Farayi Musharavati, Fadi Jaber, Mohamed Nasor, Masoud Sarraf, Erfan Zal Nezhad, Kaan Uzun, Ye Ma, Sungchul Bae, Ramesh Singh, Muhammad E. H. Chowdhury
Summary: This study investigated the mechanical properties, wettability, and tribology of hydroxyapatite-zirconia-carbon nanotube ceramic nanocomposites with different carbon nanotube ratios (1%, 5%, 10%). The results showed that the hardness of the materials increased with the addition of 1% and 5% carbon nanotubes, but decreased with the addition of 10% carbon nanotubes. In addition, the nanocomposite with 10% carbon nanotubes exhibited the highest hydrophilicity.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Ceramics
C. M. Mardziah, S. Ramesh, Hari Chandran, Amritpal Sidhu, S. Krishnasamy
Summary: In recent years, there has been extensive research on the development of hydroxyapatite (HA) using calcium from natural resources. However, most studies focused on pristine HA without incorporating dopants for strengthening. This study prepared HA bioceramic using waste chicken eggshells calcium with various concentrations of zinc dopant, and found that 5 mol% zinc-doped HA exhibited the best properties after sintering at 1250 degrees C. The improvement in fracture toughness was attributed to the formation of beta-TCP phase and enhanced densification.
CERAMICS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Melania Maglio, Maria Sartori, Alessandro Gambardella, Tatiana Shelyakova, Valentin Alek Dediu, Matteo Santin, Yolanda Pineiro, Manuel Banobre Lopez, Jose Rivas, Anna Tampieri, Simone Sprio, Lucia Martini, Alessandro Gatti, Alessandro Russo, Gianluca Giavaresi, Milena Fini
Summary: The use of functionalized scaffolds incorporated with superparamagnetic nanoparticles and vascular endothelial growth factor (VEGF) injection into a magnetic scaffold resulted in increased bone regeneration in a large bone defect in sheep metatarsus. The magnetic field generated by implanted magnets allowed the capture of the injected nanoparticles, forming a VEGF gradient in the scaffold's porosity. Histomorphometric measurements showed improved bone growth and bone-to-implant contact, while atomic force microscopy (AFM) analysis revealed similar nanomechanical behavior of the regenerated tissue to the magnetic field distribution. This study demonstrates the potential of magnetic technologies combined with functionalized scaffolds to enhance bone formation and improve bone/scaffold interaction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Hongling Bie, Honghao Chen, Lijun Shan, C. Y. Tan, M. S. H. Al-Furjan, S. Ramesh, Youping Gong, Y. F. Liu, R. G. Zhou, Weibo Yang, Honghua Wang
Summary: In this study, 3D printing technology was used to fabricate and investigate artificial bone composites based on HA-ZrO2-PVA, which have similar mechanical properties and biocompatibility to natural bone. The optimized 3D printing process parameters resulted in artificial bone scaffolds with good mechanical properties and biocompatibility.
Article
Chemistry, Multidisciplinary
Susana I. L. Gomes, Bruno Guimaraes, Elisabetta Campodoni, Monica Sandri, Simone Sprio, Magda Blosi, Anna L. Costa, Janeck J. Scott-Fordsmand, Monica J. B. Amorim
Summary: Developments in nanotechnology must ensure compliance with regulatory requirements, with a focus on safety and sustainability. Nanobiomaterials offer significant advantages in biomedical applications, but their ecotoxicological effects require further investigation to ensure safety.
Article
Environmental Sciences
Bruno Guimaraes, Susana I. L. Gomes, Elisabetta Campodoni, Monica Sandri, Simone Sprio, Magda Blosi, Anna L. Costa, Monica J. B. Amorim, Janeck J. Scott-Fordsmand
Summary: This study assessed the ecotoxicological impact of five ion-doped hydroxyapatite (HA) nanomaterials on the soil ecosystem using Folsomia candida as a model species. The results showed a compromise between reproduction and growth in response to the nanomaterials, indicating potential long-term ecological toxicity effects. Therefore, at least two generations of testing are recommended to evaluate the toxicity of nanomaterials.
Review
Chemistry, Medicinal
Anna Tampieri, Elizaveta Kon, Monica Sandri, Elisabetta Campodoni, Massimiliano Dapporto, Simone Sprio
Summary: The degeneration of osteochondral tissue is a major cause of disability in modern society and there is a growing demand for solutions to repair and regenerate damaged articular joints. Osteoarthritis is the most common complication in articular diseases and a leading cause of chronic disability. Regenerating osteochondral defects is a challenging task in orthopedics, but marine-derived ingredients hold promise for their unique properties and potential biomedical applications.
Article
Materials Science, Ceramics
Ignatius Y. Lim, C. H. Ting, C. K. Ng, J. Y. Tey, W. H. Yeo, S. Ramesh, K. Y. Sara Lee, Y. D. Chuah, W. D. Teng
Summary: In this study, 3Y-TZP ceramic feedstocks with different solid loadings were successfully prepared and printed using a screw-based 3D printing technique. The samples obtained after debinding and sintering showed desired density, hardness, and fracture toughness. The results demonstrated the feasibility of 3D printing granular 3Y-TZP ceramic feedstocks with high solid loadings.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Physical
Yong Chen, Youping Gong, Lijun Shan, Chou Yong Tan, M. S. Al-Furjan, S. Ramesh, Huipeng Chen, Xiangjuan Bian, Yanda Chen, Yunfeng Liu, Rougang Zhou
Summary: In this study, the application of biological 3D printing in manufacturing new cartilage scaffolds for cartilage regeneration was explored. The addition of hydroxyapatite (HA) enhanced the mechanical properties of the hydrogel made from sodium alginate (SA) and gelatin (GA). Different concentrations of SA-GA-HA composite hydrogel cartilage scaffolds were prepared, and better formulations for printing and testing were obtained. The printed cartilage scaffold showed useful mechanical properties and higher cell survival rate after one week, suggesting that it provides a new scaffold strategy for cartilage tissue regeneration.
Proceedings Paper
Materials Science, Multidisciplinary
K. Y. Sara Lee, Seri Rahayu Pg Ya'akub, C. K. Ng, S. Ramesh
Summary: The low-temperature degradation behavior of undoped and copper oxide-doped yttria-tetragonal zirconia polycrystal (Y-TZP) samples via microwave sintering was studied. The results showed that there was no significant difference in microstructure or grain size between microwave and conventional sintered samples at temperatures above 1250°C. Monoclinic phase was not detected after 200 hours of hydrothermal aging, regardless of sintering methods or temperature. It was also observed that the beneficial effect of microwave diminished at elevated temperatures.
MATERIALS TODAY-PROCEEDINGS
(2022)
Proceedings Paper
Materials Science, Multidisciplinary
A. N. Natasha, S. Ramesh, L. T. Bang, M. H. Koay
Summary: Hydroxyapatite (HA) is widely used in the biomedical field due to its structural resemblance to natural bone, as well as its bioactivity and thermodynamic stability in body fluid. This study successfully synthesized flower-like HA powder using a direct solid-state method with a calcium source from calcined discarded eggshells. The influence of different calcination temperatures on the stability, particle size, and morphology of HA was studied.
MATERIALS TODAY-PROCEEDINGS
(2022)
Article
Engineering, Multidisciplinary
L. T. Bang, S. Ramesh, Bui Duc Long, Nguyen Anh Son, Tran Bao Trung, S. Sivakumar
Summary: Beta tricalcium phosphate (beta-TCP) has excellent biodegradability and biocompatibility, making it a promising bone substitute material. This study successfully synthesized beta-TCP and evaluated its mechanical properties. The pure beta-TCP showed good mechanical strength and cell attachment ability.
JOURNAL OF ENGINEERING SCIENCE AND TECHNOLOGY
(2022)
