Polycystin-1, 2, and STIM1 Interact with IP3R to Modulate ER Ca2+ Release through the PI3K/Akt Pathway

The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation

(2010) S. Mangos et al.   Disease Models & Mechanisms

Polycystin-2 Activation by Inositol 1,4,5-Trisphosphate-induced Ca2+Release Requires Its Direct Association with the Inositol 1,4,5-Trisphosphate Receptor in a Signaling Microdomain

(2010) Eva Sammels et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Polycystin-1 Cleavage Product, P100, That Regulates Store Operated Ca2+ Entry through Interactions with STIM1

(2010) Owen M. Woodward et al.   PLoS One

Ca2+-dependent Conformational Changes in a C-terminal Cytosolic Domain of Polycystin-2

(2009) Frank Schumann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polycystin-1 Interacts with Inositol 1,4,5-Trisphosphate Receptor to Modulate Intracellular Ca2+Signaling with Implications for Polycystic Kidney Disease

(2009) Yun Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Store-operated cyclic AMP signalling mediated by STIM1

(2009) Konstantinos Lefkimmiatis et al.   NATURE CELL BIOLOGY

Akt kinase reducing endoplasmic reticulum Ca2+ release protects cells from Ca2+-dependent apoptotic stimuli

(2008) Saverio Marchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Small-Molecule CFTR Inhibitors Slow Cyst Growth in Polycystic Kidney Disease

(2008) B. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Calcium, cyclic AMP, and MAP kinases: Dysregulation in polycystic kidney disease

(2008) B.D. Cowley   KIDNEY INTERNATIONAL

Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2

(2008) L. Geng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA