Rho-Kinase Inhibitor, Fasudil, Prevents Neuronal Apoptosis via the Akt Activation and PTEN Inactivation in the Ischemic Penumbra of Rat Brain

ROCK inhibition prevents tau hyperphosphorylation and p25/CDK5 increase after global cerebral ischemia.

(2011) John Fredy Castro-Alvarez et al.   BEHAVIORAL NEUROSCIENCE

Rho kinase inhibition protects CA1 cells in organotypic hippocampal slices during in vitro ischemia

(2009) Lennart Gisselsson et al.   BRAIN RESEARCH

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Demonstration of elevation and localization of Rho-kinase activity in the brain of a rat model of cerebral infarction

(2008) Kazuo Yano et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Isoflurane preconditioning increases B-cell lymphoma-2 expression and reduces cytochrome c release from the mitochondria in the ischemic penumbra of rat brain

(2008) Liaoliao Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Wide therapeutic time window for Rho-kinase inhibition therapy in ischemic brain damage in a rat cerebral thrombosis model

(2007) Shin-ichi Satoh et al.   BRAIN RESEARCH