标题
TPX2: of spindle assembly, DNA damage response, and cancer
作者
关键词
TPX2, Cytoskeleton, Mitosis, Spindle, Cell cycle, DNA damage, Cancers
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 71, Issue 16, Pages 3027-3047
出版商
Springer Nature
发表日期
2014-02-21
DOI
10.1007/s00018-014-1582-7
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Upregulation of the TPX2 gene is associated with enhanced tumor malignance of esophageal squamous cell carcinoma
- (2013) Hong-Chun Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- Branching Microtubule Nucleation in Xenopus Egg Extracts Mediated by Augmin and TPX2
- (2013) Sabine Petry et al. CELL
- Overexpressed TPX2 causes ectopic formation of microtubular arrays in the nuclei of acentrosomal plant cells
- (2013) Beáta Petrovská et al. JOURNAL OF EXPERIMENTAL BOTANY
- TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma
- (2013) Po-Kuei Hsu et al. JOURNAL OF GASTROENTEROLOGY
- Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2
- (2013) Likun Li et al. Molecular Oncology
- Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
- (2013) J.-M. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Target protein for Xklp2 (TPX2), a microtubule-related protein, contributes to malignant phenotype in bladder carcinoma
- (2013) Liang Yan et al. TUMOR BIOLOGY
- Tpx2 Controls Spindle Integrity, Genome Stability, and Tumor Development
- (2012) C. Aguirre-Portoles et al. CANCER RESEARCH
- A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex
- (2012) Jyoti Iyer et al. CELLULAR SIGNALLING
- A Small-Molecule Inhibitor Targeting the Mitotic Spindle Checkpoint Impairs the Growth of Uterine Leiomyosarcoma
- (2012) W. Shan et al. CLINICAL CANCER RESEARCH
- Targeting Protein forXenopusKinesin-like Protein 2 (TPX2) Regulates γ-Histone 2AX (γ-H2AX) Levels upon Ionizing Radiation
- (2012) Gernot Neumayer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ashwagandha Derived Withanone Targets TPX2-Aurora A Complex: Computational and Experimental Evidence to its Anticancer Activity
- (2012) Abhinav Grover et al. PLoS One
- High-Throughput Transcriptomic and RNAi Analysis Identifies AIM1, ERGIC1, TMED3 and TPX2 as Potential Drug Targets in Prostate Cancer
- (2012) Paula Vainio et al. PLoS One
- Integrated cross-species transcriptional network analysis of metastatic susceptibility
- (2012) Y. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- γ-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer
- (2012) Dimitrios Matthaios et al. OncoTargets and Therapy
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Give me a break, but not in mitosis
- (2011) Simona Giunta et al. CELL CYCLE
- Interkinetic nuclear migration: cell cycle on the move
- (2011) Filippo Del Bene EMBO JOURNAL
- Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain
- (2011) Yoichi Kosodo et al. EMBO JOURNAL
- TPX2andAURKApromote 20q amplicon-driven colorectal adenoma to carcinoma progression
- (2011) Anke H Sillars-Hardebol et al. GUT
- Withanone binds to mortalin and abrogates mortalin–p53 complex: Computational and experimental evidence
- (2011) Abhinav Grover et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle
- (2011) Nan Ma et al. JOURNAL OF CELL BIOLOGY
- BRCA1 tumour suppression occurs via heterochromatin-mediated silencing
- (2011) Quan Zhu et al. NATURE
- Plant Aurora kinases play a role in maintenance of primary meristems and control of endoreduplication
- (2011) Beáta Petrovská et al. NEW PHYTOLOGIST
- PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
- (2011) P. V. Hornbeck et al. NUCLEIC ACIDS RESEARCH
- The Pfam protein families database
- (2011) M. Punta et al. NUCLEIC ACIDS RESEARCH
- Identification of a TPX2-Like Microtubule-Associated Protein in Drosophila
- (2011) Gohta Goshima PLoS One
- Constitutive expression of γ-H2AX has prognostic relevance in triple negative breast cancer
- (2011) Anika Nagelkerke et al. RADIOTHERAPY AND ONCOLOGY
- Quantitative Phosphoproteomics Identifies Substrates and Functional Modules of Aurora and Polo-Like Kinase Activities in Mitotic Cells
- (2011) A. N. Kettenbach et al. Science Signaling
- Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer
- (2011) Christopher A. Maxwell et al. PLOS BIOLOGY
- Expression of targeting protein for Xenopus kinesin-like protein 2 is associated with progression of human malignant astrocytoma
- (2010) Bin Li et al. BRAIN RESEARCH
- Examination of the expanding pathways for the regulation of p21 expression and activity
- (2010) Yong-Sam Jung et al. CELLULAR SIGNALLING
- Combined Functional Genome Survey of Therapeutic Targets for Hepatocellular Carcinoma
- (2010) R. Satow et al. CLINICAL CANCER RESEARCH
- Mechanisms of Chromosomal Instability
- (2010) Sarah L. Thompson et al. CURRENT BIOLOGY
- Cortical progenitor expansion, self-renewal and neurogenesis—a polarized perspective
- (2010) Simone A Fietz et al. CURRENT OPINION IN NEUROBIOLOGY
- Uncovering new substrates for Aurora A kinase
- (2010) Teresa Sardon et al. EMBO REPORTS
- Expression of γ-H2AX in endometrial carcinomas: An immunohistochemical study with p53
- (2010) Andreas H. Brunner et al. GYNECOLOGIC ONCOLOGY
- Novel Binding of the Mitotic Regulator TPX2 (Target Protein forXenopusKinesin-like Protein 2) to Importin-α
- (2010) Astrid Giesecke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A
- (2010) Poonam R. Molli et al. JOURNAL OF CELL BIOLOGY
- DNA damage signaling in response to double-strand breaks during mitosis
- (2010) Simona Giunta et al. JOURNAL OF CELL BIOLOGY
- Control of Aurora-A stability through interaction with TPX2
- (2010) M. Giubettini et al. JOURNAL OF CELL SCIENCE
- Identification of Gene Markers Associated With Aggressive Meningioma by Filtering Across Multiple Sets of Gene Expression Arrays
- (2010) Jourdan E. Stuart et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Poleward Transport of TPX2 in the Mammalian Mitotic Spindle Requires Dynein, Eg5, and Microtubule Flux
- (2010) Nan Ma et al. MOLECULAR BIOLOGY OF THE CELL
- Genomic instability — an evolving hallmark of cancer
- (2010) Simona Negrini et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs
- (2010) Stefan M. Berger et al. NUCLEIC ACIDS RESEARCH
- Identification of Candidate Growth Promoting Genes in Ovarian Cancer through Integrated Copy Number and Expression Analysis
- (2010) Manasa Ramakrishna et al. PLoS One
- Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signaling
- (2010) Nashi Widodo et al. PLoS One
- Amplicon-Dependent CCNE1 Expression Is Critical for Clonogenic Survival after Cisplatin Treatment and Is Correlated with 20q11 Gain in Ovarian Cancer
- (2010) Dariush Etemadmoghadam et al. PLoS One
- Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation
- (2010) V. Joukov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Short exposure to paclitaxel induces multipolar spindle formation and aneuploidy through promotion of acentrosomal pole assembly
- (2010) MingLei Bian et al. Science China-Life Sciences
- Mitotic functions of kinesin-5
- (2010) Nick P. Ferenz et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Guiding Neuronal Cell Migrations
- (2010) O. Marin et al. Cold Spring Harbor Perspectives in Biology
- Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System
- (2009) H. Kadara et al. Cancer Prevention Research
- Aurora-A and hBora Join the Game of Polo
- (2009) L. Macurek et al. CANCER RESEARCH
- Validation of TPX2 as a Potential Therapeutic Target in Pancreatic Cancer Cells
- (2009) S. L. Warner et al. CLINICAL CANCER RESEARCH
- Spindle Assembly in the Absence of a RanGTP Gradient Requires Localized CPC Activity
- (2009) Thomas J. Maresca et al. CURRENT BIOLOGY
- The Role of Hklp2 in the Stabilization and Maintenance of Spindle Bipolarity
- (2009) David Vanneste et al. CURRENT BIOLOGY
- Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas
- (2009) Shigeishi INTERNATIONAL JOURNAL OF ONCOLOGY
- A Cancer-associated Aurora A Mutant Is Mislocalized and Misregulated Due to Loss of Interaction with TPX2
- (2009) Rachel Ann Bibby et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase
- (2009) D. K. Moss et al. JOURNAL OF CELL SCIENCE
- Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells
- (2009) Christopher D Scharer et al. Journal of Translational Medicine
- Aurora A moonlights in neurite extension
- (2009) Gloria Kuo Lefkowitz et al. NATURE CELL BIOLOGY
- An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics
- (2009) Daisuke Mori et al. NATURE CELL BIOLOGY
- Crosstalk between histone modifications during the DNA damage response
- (2009) Haico van Attikum et al. TRENDS IN CELL BIOLOGY
- Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes
- (2008) M. Kwon et al. GENES & DEVELOPMENT
- Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: Potential role in progression
- (2008) Luigi Scotto et al. GENES CHROMOSOMES & CANCER
- Ndel1 Controls the Dynein-mediated Transport of Vimentin during Neurite Outgrowth
- (2008) Su Yeon Shim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A
- (2008) Alexander W. Bird et al. JOURNAL OF CELL BIOLOGY
- Pdx-1-Driven Overexpression of Aurora A Kinase Induces Mild Ductal Dysplasia of Pancreatic Ducts Near Islets in Transgenic Mice
- (2008) Steven L. Warner et al. PANCREAS
- The Plant TPX2 Protein Regulates Prospindle Assembly before Nuclear Envelope Breakdown
- (2008) J. W. Vos et al. PLANT CELL
- Ndel1 Promotes Axon Regeneration via Intermediate Filaments
- (2008) Cory Toth et al. PLoS One
- Meiotic Regulation of TPX2 Protein Levels Governs Cell Cycle Progression in Mouse Oocytes
- (2008) Stéphane Brunet et al. PLoS One
- An Oncogene-Induced DNA Damage Model for Cancer Development
- (2008) T. D. Halazonetis et al. SCIENCE
- TPX2 in malignantly transformed human bronchial epithelial cells by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide
- (2008) Lijuan Zhang et al. TOXICOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search