Transcriptional control of CD4 and CD8 coreceptor expression during T cell development

Thpok-independent repression ofRunx3by Gata3 during CD4+T-cell differentiation in the thymus

(2013) Yumei Xiong et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cutting Edge: Fine-Tuning of Thpok Gene Activation by an Enhancer in Close Proximity to Its Own Silencer

(2013) S. Muroi et al.   JOURNAL OF IMMUNOLOGY

Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II–restricted cytotoxic T lymphocytes

(2013) Daniel Mucida et al.   NATURE IMMUNOLOGY

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity

(2013) Bernardo Sgarbi Reis et al.   NATURE IMMUNOLOGY

The Transcription Factors Thpok and LRF Are Necessary and Partly Redundant for T Helper Cell Differentiation

(2012) Andrea C. Carpenter et al.   IMMUNITY

E Protein Transcription Factors Are Required for the Development of CD4+ Lineage T Cells

(2012) Mary Elizabeth Jones-Mason et al.   IMMUNITY

POZ-, AT-hook-, and Zinc Finger-containing Protein (PATZ) Interacts with Human Oncogene B Cell Lymphoma 6 (BCL6) and Is Required for Its Negative Autoregulation

(2012) Raffaela Pero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Embryonic defects and growth alteration in mice with homozygous disruption of thePatz1gene

(2012) Teresa Valentino et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus

(2012) Tom M. McCaughtry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epigenetic Silencing of Cd8 Genes by ThPOK-Mediated Deacetylation during CD4 T Cell Differentiation

(2012) J. Rui et al.   JOURNAL OF IMMUNOLOGY

Signaling in thymic selection

(2011) Nicholas RJ Gascoigne et al.   CURRENT OPINION IN IMMUNOLOGY

Coreceptor gene imprinting governs thymocyte lineage fate

(2011) Stanley Adoro et al.   EMBO JOURNAL

RUNX Transcription Factor-Mediated Association of Cd4 and Cd8 Enables Coordinate Gene Regulation

(2011) Amélie Collins et al.   IMMUNITY

Nuclear hormone receptor co-repressors: Structure and function

(2011) Peter J. Watson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Ikaros gene family: Transcriptional regulators of hematopoiesis and immunity

(2011) Liza B. John et al.   MOLECULAR IMMUNOLOGY

Control of the development of CD8αα+ intestinal intraepithelial lymphocytes by TGF-β

(2011) Joanne E Konkel et al.   NATURE IMMUNOLOGY

Cd8 enhancer E8I and Runx factors regulate CD8  expression in activated CD8+ T cells

(2011) H. Hassan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene

(2011) T. Egawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of ThPOK in Control of CD4/CD8 Lineage Commitment

(2010) Xi He et al.   Annual Review of Immunology

TCR-mediated ThPOK induction promotes development of mature (CD24−) γδ thymocytes

(2010) Kyewon Park et al.   EMBO JOURNAL

Bcl11b represses a mature T-cell gene expression program in immature CD4+CD8+ thymocytes

(2010) Philippe Kastner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells

(2010) M. M. W. Chong et al.   GENES & DEVELOPMENT

Antigen-specific clonal expansion and cytolytic effector function of CD8+T lymphocytes depend on the transcription factor Bcl11b

(2010) Shuning Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8 Locus Nuclear Dynamics during Thymocyte Development

(2010) E. Ktistaki et al.   JOURNAL OF IMMUNOLOGY

The L2a element is a mouse CD8 silencer that interacts with MAR-binding proteins SATB1 and CDP

(2010) Xin Yao et al.   MOLECULAR IMMUNOLOGY

Another zinc finger in the pie of CD4-CD8 lineage choice

(2010) Kensuke Takada et al.   NATURE IMMUNOLOGY

Decision checkpoints in the thymus

(2010) Andrea C Carpenter et al.   NATURE IMMUNOLOGY

The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes

(2010) Shinya Sakaguchi et al.   NATURE IMMUNOLOGY

Towards a molecular understanding of the differential signals regulating αβ/γδ T lineage choice

(2010) Sang-Yun Lee et al.   SEMINARS IN IMMUNOLOGY

Genome-wide Lineage-Specific Transcriptional Networks Underscore Ikaros-Dependent Lymphoid Priming in Hematopoietic Stem Cells

(2009) Samuel Yao-Ming Ng et al.   IMMUNITY

New insights into the functions and regulation of the transcriptional corepressors SMRT and N-CoR

(2009) Kristopher J Stanya et al.   Cell Division

The Zinc Finger Transcription Factor Zbtb7b Represses CD8-Lineage Gene Expression in Peripheral CD4+ T Cells

(2008) Lie Wang et al.   IMMUNITY

CD4-CD8 Lineage Commitment Is Regulated by a Silencer Element at the ThPOK Transcription-Factor Locus

(2008) Xi He et al.   IMMUNITY

Development of all CD4 T lineages requires nuclear factor TOX

(2008) Parinaz Aliahmad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PATZ1 gene has a critical role in the spermatogenesis and testicular tumours

(2008) M Fedele et al.   JOURNAL OF PATHOLOGY

SATB1 is required for CD8 coreceptor reversal

(2008) Hui Nie et al.   MOLECULAR IMMUNOLOGY

Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate

(2008) Sawako Muroi et al.   NATURE IMMUNOLOGY

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

(2008) Takeshi Egawa et al.   NATURE IMMUNOLOGY

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells

(2008) Lie Wang et al.   NATURE IMMUNOLOGY

Nucleoprotein structure of the CD4 locus: Implications for the mechanisms underlying CD4 regulation during T cell development

(2008) M. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repression of the Transcription Factor Th-POK by Runx Complexes in Cytotoxic T Cell Development

(2008) R. Setoguchi et al.   SCIENCE